Results 11 to 20 of about 19,015,309 (380)

Do stress responses promote leukemia progression? An animal study suggesting a role for epinephrine and prostaglandin-E2 through reduced NK activity. [PDF]

PLoS ONE, 2011
In leukemia patients, stress and anxiety were suggested to predict poorer prognosis. Oncological patients experience ample physiological and psychological stress, potentially leading to increased secretion of stress factors, including epinephrine ...
Shelly Inbar, Elad Neeman, Roi Avraham, Marganit Benish, Ella Rosenne, Shamgar Ben-Eliyahu   +5 more
doaj   +1 more source

Inflamm-aging and arachadonic acid metabolite differences with stage of tendon disease. [PDF]

PLoS ONE, 2012
The contribution of inflammation to the pathogenesis of tendinopathy and high prevalence of re-injury is not well established, although recent evidence suggests involvement of prostaglandins.
Stephanie Georgina Dakin, Jayesh Dudhia, Natalie Jayne Werling, Dirk Werling, Dilkush Robert Ephrem Abayasekara, Roger Kenneth Whealands Smith   +5 more
doaj   +1 more source

Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide

Molecular and Cellular Biology, 1994
Induction of interleukin-6 (IL-6) gene expression is mediated by numerous agents involving all major signal transduction pathways. We have compared the effects of prostaglandins and their second messenger cyclic AMP (cAMP) with the effect of ...
Ulrich Dendorfer, Peter Oetfgen, T. Libermann   +2 more
semanticscholar   +1 more source

Contribution of PGE2 EP1 receptor in hemin-induced neurotoxicity

Frontiers in Molecular Neuroscience, 2013
Although hemin-mediated neurotoxicity has been linked to the production of free radicals and glutamate excitotoxicity, the role of the prostaglandin E2 (PGE2)-EP1 receptor remains unclear.
Shekher eMohan, Alexander V. Glushakov, Alexander edeCurnou, Shuh eNarumiya, Sylvain eDoré   +4 more
doaj   +1 more source

Insights into the prostanoid pathway in the ovary development of the penaeid shrimp Penaeus monodon. [PDF]

PLoS ONE, 2013
The prostanoid pathway converts polyunsaturated fatty acids (PUFAs) into bioactive lipid mediators, including prostaglandins, thromboxanes and prostacyclins, all of which play vital roles in the immune and reproductive systems in most animal phyla.
Wananit Wimuttisuk, Punsa Tobwor, Pacharawan Deenarn, Kannawat Danwisetkanjana, Decha Pinkaew, Kanyawim Kirtikara, Vanicha Vichai   +6 more
doaj   +1 more source

Hypothyroidism Affects Uterine Function via the Modulation of Prostaglandin Signaling

Animals, 2021
Thyroid hormones control the functions of almost all body systems. Reproductive dysfunctions, such as abnormal sexual development, infertility, or irregularities in the reproductive cycle, might be associated with thyroid disorders.
Ilona Kowalczyk-Zieba, Joanna Staszkiewicz-Chodor, Dorota Boruszewska, Krzysztof Lukaszuk, Joanna Jaworska, Izabela Woclawek-Potocka   +5 more
doaj   +1 more source

Docosahexaenoic acid-rich algae oil supplementation in mothers of preterm infants is associated with a modification in breast milk oxylipins profile

Lipids in Health and Disease, 2023
Oxylipins are derived from enzymatic and non-enzymatic oxidation of n-3 and n-6 long-chain polyunsaturated fatty acids. They are known to be involved in inflammatory processes.
Hélène Fougère, Karine Greffard, Mireille Guillot, Iwona Rudkowska, Etienne Pronovost, David Simonyan, Isabelle Marc, Jean-François Bilodeau   +7 more
doaj   +1 more source

Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS‐1 (832/3) cell glucose‐stimulated insulin secretion

Pharmacology Research & Perspectives, 2021
Chronic elevations in fatty acid metabolites termed prostaglandins can be found in circulation and in pancreatic islets from mice or humans with diabetes and have been suggested as contributing to the β‐cell dysfunction of the disease.
Harpreet K. Sandhu, Joshua C. Neuman, Michael D. Schaid, Sarah E. Davis, Kelsey M. Connors, Romith Challa, Erin Guthery, Rachel J. Fenske, Chinmai Patibandla, Richard M. Breyer, Michelle E. Kimple   +10 more
doaj   +1 more source

Gastroprotective activity of (E)-ethyl-12-cyclohexyl-4,5-dihydroxydodec-2-enoate, a compound isolated from Heliotropium indicum: role of nitric oxide, prostaglandins, and sulfhydryls in its mechanism of action

Pharmaceutical Biology, 2022
Context The gastroprotective effect of Heliotropium indicum L. (Boraginaceae), a plant traditionally used in Mexico to treat gastric ulcers, has been previously reported. However, no active compound was identified.Objective The current contribution aimed
Yaraset López-Lorenzo, María Elena Sánchez-Mendoza, Daniel Arrieta-Baez, Adriana Guadalupe Perez-Ruiz, Jesús Arrieta   +4 more
doaj   +1 more source

Influence of prostaglandins on DNA and matrix synthesis in growth plate chondrocytes

Journal of Bone and Mineral Research, 1992
Prostaglandins are locally produced in a number of tissues in response to a variety of stimuli, including local growth factors and systemic hormones. The present investigation characterizes prostaglandin effects on growth plate chondrocytes. Since cyclic
R. O’Keefe, I. D. Crabb, J. Puzas, R. Rosier   +3 more
semanticscholar   +1 more source