Nature Communications, 2023 Prostaglandins and their receptors regulate various physiological processes. Carboprost, an analog of prostaglandin F2α and an agonist for the prostaglandin F2-alpha receptor (FP receptor), is clinically used to treat postpartum hemorrhage (PPH). However,
Xiuqing Lv +12 more
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Do stress responses promote leukemia progression? An animal study suggesting a role for epinephrine and prostaglandin-E2 through reduced NK activity. [PDF]
PLoS ONE, 2011 In leukemia patients, stress and anxiety were suggested to predict poorer prognosis. Oncological patients experience ample physiological and psychological stress, potentially leading to increased secretion of stress factors, including epinephrine ...
Shelly Inbar +5 more
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Inflamm-aging and arachadonic acid metabolite differences with stage of tendon disease. [PDF]
PLoS ONE, 2012 The contribution of inflammation to the pathogenesis of tendinopathy and high prevalence of re-injury is not well established, although recent evidence suggests involvement of prostaglandins.
Stephanie Georgina Dakin +5 more
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Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms [PDF]
, 2018 Platelet-activating factor (PAF) stimulates numerous cell types via activation of the G protein-coupled PAF receptor (PAFR). PAFR activation not only induces acute proinflammatory responses, but it also induces delayed systemic immunosuppressive effects ...
FitzGerald, Garret A. +6 more
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Contribution of PGE2 EP1 receptor in hemin-induced neurotoxicity
Frontiers in Molecular Neuroscience, 2013 Although hemin-mediated neurotoxicity has been linked to the production of free radicals and glutamate excitotoxicity, the role of the prostaglandin E2 (PGE2)-EP1 receptor remains unclear.
Shekher eMohan +4 more
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Biology of Reproduction, 1988 This study establishes that ovulated female goldfish release F type prostaglandins (PGFs) to the water where they stimulate male spawning behavior and comprise the goldfish postovulatory pheromone.
P. Sorensen +3 more
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Insights into the prostanoid pathway in the ovary development of the penaeid shrimp Penaeus monodon. [PDF]
PLoS ONE, 2013 The prostanoid pathway converts polyunsaturated fatty acids (PUFAs) into bioactive lipid mediators, including prostaglandins, thromboxanes and prostacyclins, all of which play vital roles in the immune and reproductive systems in most animal phyla.
Wananit Wimuttisuk +6 more
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Polyunsaturated fatty acid-derived lipid mediators and T cell function [PDF]
, 2011 Copyright © 2014 Nicolaou, Mauro, Urquhart and Marelli-Berg . This is an open- access article distributed under the terms of the Creative Commons Attribution License (CC BY) .
Nicolaou, A +3 more
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Prostaglandins - universal biological regulators in the human body (literature review)
Zaporožskij Medicinskij Žurnal, 2018 Recently, researchers of different industries pay great attention to the problem of prostaglandins. Objective: to study and systematize the basic questions of structure, biological action and metabolism of prostaglandins in the human body and using ...
О. V. Tymoshchuk +2 more
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Hypothyroidism Affects Uterine Function via the Modulation of Prostaglandin Signaling
Animals, 2021 Thyroid hormones control the functions of almost all body systems. Reproductive dysfunctions, such as abnormal sexual development, infertility, or irregularities in the reproductive cycle, might be associated with thyroid disorders.
Ilona Kowalczyk-Zieba +5 more
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