Results 251 to 260 of about 63,897 (315)

Protective Effects of Human Milk Oligosaccharides (hMOs) on Analgesic, Nonsteroidal Anti‐inflammatory Drugs (NSAIDs)‐Induced Disruption of Gut Barrier Integrity in Cocultures Mimicking Neuro‐Gut Epithelial Cell Crosstalk

Molecular Nutrition &Food Research, EarlyView.
Nerve cells partially mitigate indomethacin‐induced tight junction dysregulation in neuro‐gut epithelial cell cocultures. Human milk oligosaccharides 2′‐ and 3‐fucosyllactose (2′‐FL and 3‐FL) protect the neuro‐gut epithelial barrier from indomethacin‐induced damage. This protection is stronger in cocultures with higher nerve cell densities.
Xiaochen Chen, Naschla Gasaly, Marthe T. C. Walvoort, Paul de Vos   +3 more
wiley   +1 more source

Bioactive lipid mediator class switching regulates myogenic cell progression and muscle regeneration. [PDF]

Nat Commun
Fabre P, Molina T, Larose J, Greffard K, Généreux-Gamache G, Deprez A, Mokhtari I, Pellerito O, Duchesne E, Dort J, Bilodeau JF, Dumont NA.   +11 more
europepmc   +1 more source

Mitochondrial transfer as a novel therapeutic approach in ischemic stroke treatment: Current challenges and future perspectives

Neuroprotection, EarlyView.
Cerebral ischemia is a serious neurological disease that mainly leads to pathological changes such as mitochondrial dysfunction, oxidative stress and iron death. Mitochondria play a key role in the regulation of cellular energy metabolism and oxidative stress, and their damage can lead to mitochondrial damage, reduced adenosine triphosphate production,
Shuchen Meng, Min Bai, Changsheng Ma, Bo Han, Mengyuan Duan, Liying Zhang, Jinfen Guo, Changku Shi, Ke Li, Maotao He   +9 more
wiley   +1 more source

Evaluating the Anti-inflammatory Efficacy of Steroids, COX-2 Selective, and Nonselective NSAIDs in Contusion Spinal Cord Injury: An Experimental Analysis.

J Pharm Bioallied Sci
Balachandran SK, Iyer K, Senthil SA, Ramalingam AP, Venkatachalam S.   +4 more
europepmc   +1 more source

Prostaglandins Differentially Regulate the Constitutive and Mechanosensitive Release of Soluble Nucleotidases in the Urinary Bladder Mucosa. [PDF]

Int J Mol Sci
Gutierrez Cruz A, Borhani Peikani M, Beaulac TD, Mutafova-Yambolieva VN.   +3 more
europepmc   +1 more source

Role of astrocyte in neuroinflammation‐induced loss in neuroplasticity and subsequent onset of depression: A systematic review

Neuroprotection, EarlyView.
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal, Saurabh Singhal, Bernhard T. Baune   +2 more
wiley   +1 more source

Forehead flap affected by a primary varicella-zoster infection in a pediatric patient. A case report. [PDF]

SAGE Open Med Case Rep
Martínez Mejorada R, Saldívar Martínez DE, Peñarrieta Daher EA, Ochoa Cortez MF, González Cantú CM, Jaques Villarreal E, Castro-Govea Y.   +6 more
europepmc   +1 more source

Steroids for Pediatric Adenotonsillectomy Pain—A Prospective Multicenter Randomized Trial

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To compare postoperative caregiver‐reported pain control of two steroid regimens following pediatric adenotonsillectomy. Secondary objectives assessed differences in analgesic use, return to normal diet, caregiver calls, adverse effects, and emergency room (ER) visits. Study Design Prospective randomized pragmatic trial.
Kevin D. Pereira, Wiktoria A. Gocal, Anna V. Borodianski, Mary E. Williamson, Hengameh K. Behzadpour, Sonal Saraiya, Diego A. Preciado, Amal Isaiah   +7 more
wiley   +1 more source

A Case of Persistent Bilateral Irvine-Gass Syndrome Following Uneventful Cataract Surgery in a Healthy Individual. [PDF]

Cureus
Low CS, Cheng TC, Che Hamzah J, Nasaruddin RA.   +3 more
europepmc   +1 more source

Ibuprofen‐Functionalized Alkyl α‐hydroxy Methacrylate‐Based Polymers

ChemistryOpen, EarlyView.
This work describes the synthesis and evaluation of novel alkyl α‐hydroxymethacrylate‐based ibuprofen‐functionalized prodrugs to improve the bioavailability, decrease toxicity, and control drug release. Novel alkyl α‐hydroxymethacrylate‐based prodrugs are prepared to improve bioavailability, decrease toxicity, and control drug release.
Burcu Balaban, Seckin Altuncu, Aleyna Esenturk, Simay Denizkusu, Ece Sabuncu, Hande Sipahi, Duygu Avci   +6 more
wiley   +1 more source