Results 21 to 30 of about 19,015,309 (380)
British Journal of Pharmacology, 1989 1 Platelet‐activating factor (Paf) was found to stimulate leukotriene B4 release from human polymorphonuclear leukocytes (PMN). This stimulation was considerably enhanced in the presence of small amounts of exogenous arachidonic acid. 2 Prostaglandin E2 (
P. Ney, K. Schrör
semanticscholar +1 more source
Upregulation of prostaglandin E2 by inducible microsomal prostaglandin E synthase-1 in colon cancer [PDF]
Annals of Coloproctology, 2022 Purpose: Prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) is known to promote carcinogenesis and cancer progression in colon cancer. Enzymes involved in the metabolism of PGE<sub>2</sub> include cyclooxygenase (COX)-2, microsomal prostaglandin E synthase-1 (mPGES-1), and 15-prostaglandin dehydrogenase (15-PGDH).
Young Hun Kim, Kyung Jong Kim
openaire +3 more sources
Journal of Immunology, 1977 Activation of C by immunoglobulins reactive with cell surface antigens stimulated synthesis of prostaglandin E and resultant release of 45Ca from organ cultures of fetal rat bones labeled in utero.
A. Sandberg +4 more
semanticscholar +1 more source
Cells, 2021 Macrophages are professional antigen presenting cells with intense phagocytic activity, strategically distributed in tissues and cavities. These cells are capable of responding to a wide variety of innate inflammatory stimuli, many of which are signaled ...
Alma M. Astudillo +5 more
doaj +1 more source
Original Research: Critical CareThe Use of Inhaled Prostaglandins in Patients With ARDS
, 2015 OBJECTIVE: Th is study aimed to determine whether inhaled prostaglandins are associated with improvement in pulmonary physiology or mortality in patients with ARDS and assess adverse eff ects .
B. Fuller +5 more
semanticscholar +1 more source
Animal Research and One Health, EarlyView., 2023 In the present study, we created the weight gain models with Min and Yorkshire pigs and conducted the metagenomics and metabolomics of colon contents and transcriptomics of colon tissue. Further, we revealed the characteristics and functions of the colonic microbiota in Min and Yorkshire pigs and analyzed their interactions with the host. Overall, this
Xiaoyu Huang +6 more
wiley +1 more source
Mediators of Inflammation, 2015 Prostaglandin (PG) E2 and PGI2 are essential to hyperalgesia in inflammatory tissues. These prostaglandins are produced from arachidonic acid, which is cleaved from membrane phospholipids by the action of phospholipase A2 (PLA2). Which isozyme of PLA2 is
Keiichiro Tsuchida +2 more
doaj +1 more source
Biochemical warfare on the reef: the role of glutathione transferases in consumer tolerance of dietary prostaglandins. [PDF]
PLoS ONE, 2010 BACKGROUND: Despite the profound variation among marine consumers in tolerance for allelochemically-rich foods, few studies have examined the biochemical adaptations underlying diet choice. Here we examine the role of glutathione S-transferases (GSTs) in
Kristen E Whalen +3 more
doaj +1 more source
Modeling of biological doses and mechanical effects on bone transduction [PDF]
Journal of Theoretical Biology 274, 1 (2011) 36-42, 2011 Shear stress, hormones like parathyroid and mineral elements like calcium mediate the amplitude of stimulus signal which affects the rate of bone remodeling. The current study investigates the theoretical effects of different metabolic doses in stimulus signal level on bone.
arxiv +1 more source
Microsomal prostaglandin E synthase-1: the inducible synthase for prostaglandin E2.
Arthritis research & therapy, 2005 Microsomal prostaglandin E synthase-1 (mPGES-1) is an inducible enzyme that catalyzes the conversion of prostaglandin (PG)H2 to PGE2. Proinflammatory stimuli markedly increase levels of mPGES-1 expression both in vivo and in vitro. mPGES-1 knockout studies and animal models of inflammatory arthritis also provide a strong basis for the contribution of ...
Seetha U. Monrad +2 more
openaire +3 more sources