Results 81 to 90 of about 94,624 (285)
Metabolic syndrome as an independent determinant of prostate volume in elderly males over 60 years [PDF]
Journal of Men's HealthBackground: There is a high incidence of metabolic syndrome (MS) and prostate disease in elderly males over 60 years old. This study aimed to investigate the influence of MS on prostate-specific antigen (PSA) levels, prostate volume (PV) and PSA ...
Yu Chen, Gansheng Xie, Yu Li
doaj +1 more source
PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe
Advanced Science, EarlyView.This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao +14 more
wiley +1 more source
African Journal of Urology, 2018 Introduction and objectives: Several existing models have been developed to predict positive prostate biopsy among men undergoing evaluation for prostate cancer (PCa). However, most of these models have come from industrialized countries.
F.A. Yeboah +10 more
doaj +1 more source
Prostate Specific Antigen Density and Gleason Score-Is there any correlation?
, 2019 Objectives:The primary objective of the study was to correlate the Prostate Specific Antigen Density (PSAD) of prostate cancer according to its Gleason scores, and secondary objective was to correlate the PSAD of benign prostate diseases.
Aminu, S., Gunendrad, T., Syed, K.
core +1 more source
Advanced Science, EarlyView.This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
Molecular and functional analysis of the tumour antigen T21
, 2015 Immunotherapy is a valuable approach to target tumour cells by stimulating the body’s adaptive immune system. To achieve this objective, it is important to identify and study antigens that are distinctively expressed in cancer and can be used effectively
Alshehri, BM
core
Advanced Science, EarlyView.Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang +11 more
wiley +1 more source
Engineered antibody and neuropeptide mediated radionuclide targeting in prostate cancer
, 2010 PhDProstate cancer (PC) is the most common cancer type in men in the western world and to date no definitive stratergy to image PC is avaliable. This thesis explores the possibility of using Prostate Specific Membrane Antigen (PSMA) and Gastrin Releasing
Kashani, Roxana M G +1 more
core
, 2020 44Sc is an attractive positron-emitting radionuclide for PET imaging; herein, a new complex of the Sc3+ ion with nonmacrocyclic chelator H4pypa was synthesized and characterized with high-resolution electrospray-ionization mass spectrometry (HR-ESI-MS ...
Eduardo Aluicio-Sarduy (1610008) +29 more
core +1 more source
Advanced Science, EarlyView.Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao +12 more
wiley +1 more source