Results 1 to 10 of about 591 (87)

Adenocarcinoma of the esophagogastric junction: relationship between clinicopathological data and p53, cyclin D1 and Bcl-2 immunoexpressions Adenocarcinoma da junção esôfago-gástrica: relação entre os dados cllnipatológicos e a imunoexpressão de p53, ciclina D1 e Bcl-2 [PDF]

Arquivos de Gastroenterologia, 2009
CONTEXT: Esophagogastric junction adenocarcinoma has an aggressive behavior, and TNM (UICC) staging is not always accurate enough to categorize patient's outcome.
Dárcio Matenhauer Lehrbach, Ivan Cecconello, Ulysses Ribeiro Jr, Vera Luiza Capelozzi, Alexandre Muxfeldt Ab'Saber, Venâncio Avancini Ferreira Alves   +5 more
doaj   +2 more sources

Bcl-2 expression in rectal cancer Expressão da proteína bcl-2 no câncer de reto [PDF]

Arquivos de Gastroenterologia, 2006
BACKGROUD: Proteins involved in apoptosis process seem to play an important role in colorectal carcinogenesis AIM: To determine the prevalence of bcl-2 protein immunohistochemical expression and its relation with clinical and histopathological variables ...
Paulo C. Contu, Simone S. Contu, Luis F. Moreira   +2 more
doaj   +2 more sources

Cell proliferation and apoptosis in gastric cancer and intestinal metaplasia Proliferação celular e apoptose em câncer gástrico e metaplasia intestinal

Arquivos de Gastroenterologia, 2005
BACKGROUND: Higher proliferation is commonly observed in cancer cells. Apoptosis can be a useful measure of a tumor cell kinetic. Alteration of the balance between proliferation and apoptosis is associated with cancer.
Nora Manoukian Forones, Ana Paula Souza Carvalho, Oswaldo Giannotti-Filho, Laércio Gomes Lourenço, Celina Tizuko Fujiyama Oshima   +4 more
doaj   +1 more source

Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspects Queilite actínica e carcinoma espinocelular do lábio: aspectos clínicos, histopatológicos e imunogenéticos

Anais Brasileiros de Dermatologia, 2012
Actinic cheilitis is the main precancerous lesion of the lip. Squamous cell carcinoma of the lip is reported together with oral carcinomas in the Brazilian official statistics. Overall, they account for 40% of the head and neck carcinomas.
Renata Aparecida Martinez Antunes Ribeiro Vieira, Eliana Maria Minicucci, Mariangela Esther Alencar Marques, Silvio Alencar Marques   +3 more
doaj   +1 more source

Regulación de la familia de proteínas BCL-2 en células infectadas con Chlamydia trachomatis

, 2015
El presente articulo revisa los mecanismos inhibitorios de la apoptosis usados por Chlamydia trachomatis (Ct) frente a la familia de proteinas Bcl-2, para lograr su supervivencia intracelular.
Adriana Paola Jutinico Shubach, A. Galindo, R. Mora   +2 more
semanticscholar   +1 more source

Bcl-2 and c-Myc expression in oral dysplasia and oral squamous cell carcinoma: An immunohistochemical study to assess tumor progression

Journal of Oral and Maxillofacial Pathology, 2018
Introduction: Oral cancer is a multistep process involving foul play of proto-oncogenes that induce cell proliferation, inactivation of tumor suppressor gene and cessation of programmed cell death.
N. Pallavi, G. R. Nalabolu, S. Hiremath
semanticscholar   +1 more source

Desregulação da apoptose em neoplasias mieloproliferativas crônicas

Einstein (São Paulo)
As neoplasias mieloproliferativas crônicas cromossomo Filadélfia negativas são doenças hematológicas clonais que se caracterizam pela independência ou pela hipersensibilidade dos progenitores hematopoiéticos às citocinas.
Raquel Tognon, Natália de Souza Nunes, Fabíola Attié de Castro   +2 more
doaj   +1 more source

ID073 Segurança e eficácia das terapias-alvo no tratamento da leucemia linfocítica crônica (LLC): ibrutinibe e venetoclax (monoterapia ou associados à imunoterapia/ quimioimunoterapia)

Jornal de Assistência Farmacêutica e Farmacoeconomia
Introdução  A Leucemia Linfocítica Crônica (LLC) é caracterizada pelo acúmulo progressivo de linfócitos B monoclonais. Globalmente existem em torno de 191 mil casos e 61 mil mortes por ano atribuídas a LLC.
Isabel Cristina de Almeida Santiago, Aline do Nascimento, Raphael Duarte Chança, Ricardo Ribeiro Alves Fernandes, Rita de Cássia Ribeiro de Albuquerque, Cláudia Lima Vieira, Laura Augusta Barufaldi   +6 more
doaj   +1 more source

Phosphorylation of Bcl-2 Protein and Association with p21Ras in Ras-induced Apoptosis (*)

Journal of Biological Chemistry, 1996
p21Ras mediates mitogenic responses and also renders cells susceptible to apoptosis after inhibition of protein kinase C (PKC) activity. Ras-induced apoptosis can be blocked by the proto-oncogene bcl-2, but the biochemical or functional nature of Bcl-2 ...
Chang‐Yan Chen, D. Faller
semanticscholar   +1 more source

WT1 modulates apoptosis by transcriptionally upregulating the bcl‐2 proto‐oncogene

EMBO Journal, 1999
The Wilms‘ tumor suppressor gene, WT1, encodes a zinc finger transcription factor that has been demonstrated to negatively regulate several growth factor and cognate receptor genes.
M. Mayo, C. Y. Wang, S. Drouin, L. Madrid, A. Marshall, John Calvin Reed, B. Weissman, A. Baldwin   +7 more
semanticscholar   +1 more source