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Evolutionary Multi-Objective Design of SARS-CoV-2 Protease Inhibitor Candidates [PDF]
Computational drug design based on artificial intelligence is an emerging research area. At the time of writing this paper, the world suffers from an outbreak of the coronavirus SARS-CoV-2. A promising way to stop the virus replication is via protease inhibition.
arxiv +1 more source
Microbial Proteases Applications
The use of chemicals around the globe in different industries has increased tremendously, affecting the health of people. The modern world intends to replace these noxious chemicals with environmental friendly products for the betterment of life on the ...
A. Razzaq+6 more
semanticscholar +1 more source
Solid state fermentation is a promising technology largely used in biotechnology process and is a suitable strategy for producing low-cost enzymatic products.
FELYPE T.B. ROCHA+6 more
doaj +1 more source
Pollens destroy respiratory epithelial cell anchors and drive alphaherpesvirus infection [PDF]
Pollens are well-known triggers of respiratory allergies and asthma. The pollen burden in today's ambient air is constantly increasing due to rising climate change and air pollution.
Gevaert, Kris+6 more
core +3 more sources
Physiologic turnover of interstitial collagen is mediated by a sequential pathway in which collagen is fragmented by pericellular collagenases, endocytosed by collagen receptors, and routed to lysosomes for degradation by cathepsins.
Daniel Hargbøl Madsen+9 more
doaj +1 more source
Protease inhibitors targeting coronavirus and filovirus entry. [PDF]
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet+10 more
core +1 more source
Effect of accumulated resistance genes to Puccinia triticina on transfer of seed proteins [PDF]
Eighteen wheat lines and varieties were classified in four groups according to different reactions to Puccinia triticina isolate of the race 77 at seedlings.
Jerković Zoran+2 more
doaj +1 more source
A new subfamily of fungal subtilases: structural and functional analysis of a Pleurotus ostreatus member [PDF]
Pleurotus ostreatus produces several extracellular proteases which are believed to be involved in the regulation of the ligninolytic activities of this fungus. Recently, purification and characterization of the most abundant P.
FARACO, VINCENZA+5 more
core +2 more sources
The role of proteases in pathologies of the synovial joint [PDF]
Synovial (diarthrodial) joints are employed within the body to provide skeletal mobility and have a characteristic structure adapted to provide a smooth almost frictionless surface for articulation.
Buttle, D, Jones, GC, Riley, GP
core +1 more source
Sustainable Upcycling of Fisheries and Aquaculture Wastes Using Fish-Derived Cold-Adapted Proteases
The fisheries and aquaculture industries are some of the major economic sectors in the world. However, these industries generate significant amounts of wastes that need to be properly managed to avoid serious health and environmental issues.
Zied Khiari
doaj +1 more source