Author Correction: Protectin DX increases alveolar fluid clearance in rats with lipopolysaccharide-induced acute lung injury [PDF]
Experimental and Molecular MedicineXiao-Jun Zhuo +9 more
doaj +4 more sources
Protectin DX Relieve Hyperoxia‐induced Lung Injury by Protecting Pulmonary Endothelial Glycocalyx
Journal of Inflammation Research, 2023 Zhongjie Liang,1,2 Huilin Yue,1 Congcong Xu,1 Qian Wang,3 Shengwei Jin2,3 1Department of Neonatology, The Second Affiliated Hospital, Yuying Children’s Hospital of Wenzhou Medical University, Zhejiang, People’s Republic of China; 2Department of ...
Liang Z, Yue H, Xu C, Wang Q, Jin S
doaj +1 more source
Herring roe PLs promote SPM biosynthesis in macrophages and a keratinocyte/fibroblast coculture as a model of psoriasis [PDF]
Journal of Lipid ResearchPsoriasis is a chronic immune-mediated inflammatory disease affecting the skin, presenting with both local and systemic inflammation as part of its pathophysiology.
Thomas A. Ringheim-Bakka +9 more
doaj +2 more sources
Efficient One-Step Production of 7S,17S- and 10S,17S-Dihydroxydocosahexaenoic Acids by a Double-Oxygenating 15S-Lipoxygenase From Chlamydomonas incerta. [PDF]
Biotechnol BioengBiotransformation pathway from polyunsaturated fatty acids into dihydroxy fatty acids as lipid mediators by Escherichia coli expressing Chlamydomonas incerta 15S‐lipoxygenase with double oxygenating activity. The 15S‐lipoxygenase was the most efficient for the simultaneous production of resolvin D5 (7S,17S‐dihydroxydocosahexaenoic acid, 7S,17S‐DiHDHA ...
Park HA, Lee J, Oh DK.
europepmc +2 more sources
Exploring the Relationship Between Diaphragmatic Ultrasound Parameters and Lipid Mediators in Chronic Obstructive Pulmonary Disease: A Case Control Study [PDF]
American Journal of Men's HealthChronic obstructive pulmonary disease (COPD) is a progressive inflammatory disorder characterized by irreversible airflow limitation and respiratory muscle dysfunction.
Warda Jelassi +10 more
doaj +2 more sources
DHA-Derived Lipid Mediators Attenuate Osteoarthritis by Resolving Inflammation and Protecting Cartilage in Association with the SIRT1 Signaling Pathway [PDF]
Marine DrugsOsteoarthritis (OA) is a chronic degenerative joint disease characterized by persistent low-grade inflammation and progressive cartilage destruction.
Yan Su +6 more
doaj +2 more sources
Protectin DX as a therapeutic strategy against frailty in mice. [PDF]
Geroscience, 2023 AbstractFrailty in aging is driven by the dysregulation of multiple biological pathways. Protectin DX (PDX) is a docosahexaenoic acid (DHA)-derived molecule that alleviates many chronic inflammatory disorders, but its potential effects on frailty remain unknown.
Perazza LR +4 more
europepmc +3 more sources
Protectin DX Relieve Hyperoxia-induced Lung Injury by Protecting Pulmonary Endothelial Glycocalyx. [PDF]
J Inflamm Res, 2023 Bronchopulmonary dysplasia (BPD) is a common chronic lung disease in premature infants with limited treatments and poor prognosis. Damaged endothelial glycocalyx leads to vascular permeability, lung edema and inflammation. However, whether hyperoxia increases neonatal pulmonary microvascular permeability by degrading the endothelial glycocalyx remains ...
Liang Z, Yue H, Xu C, Wang Q, Jin S.
europepmc +3 more sources
Plexin C1 modulates metabolic programming for resolution of severe inflammation [PDF]
Cell Communication and SignalingPersistent, unresolved inflammatory processes disrupt the complex homeostatic state and lead to severe disease, ultimately resulting in organ failure, shock, and death.
Andreas Körner +10 more
doaj +2 more sources
Anti-inflammatory and anti-virus potential of poxytrins, especially protectin DX. [PDF]
Biochimie, 2020 Poxytrins (Pufa Oxygenated Trienes) are dihydroxy derivatives from polyunsaturated fatty acids (PUFA) with adjacent hydroxyl groups to a conjugated triene having the specific E,Z,E geometry. They are made by the double action of one lipoxygenase or the combined actions of two lipoxygenases, followed by reduction of the resulting hydroperoxides with ...
Lagarde M +2 more
europepmc +5 more sources