Results 11 to 20 of about 697,104 (329)

Anthrax toxin component, Protective Antigen, protects insects from bacterial infections. [PDF]

PLoS Pathog, 2020
Anthrax is a major zoonotic disease of wildlife, and in places like West Africa, it can be caused by Bacillus anthracis in arid nonsylvatic savannahs, and by B. cereus biovar anthracis (Bcbva) in sylvatic rainforests. Bcbva-caused anthrax has been implicated in as much as 38% of mortality in rainforest ecosystems, where insects can enhance the ...
Alameh S, Bartolo G, O'Brien S, Henderson EA, Gonzalez LO, Hartmann S, Klimko CP, Shoe JL, Cote CK, Grill LK, Levitin A, Martchenko Shilman M.   +11 more
europepmc   +5 more sources

A Quantum Vaccinomics Approach for the Design and Production of MSP4 Chimeric Antigen for the Control of Anaplasma phagocytophilum Infections

Vaccines, 2022
Anaplasma phagocytophilum Major surface protein 4 (MSP4) plays a role during infection and multiplication in host neutrophils and tick vector cells. Recently, vaccination trials with the A.
José de la Fuente, Alberto Moraga-Fernández, Pilar Alberdi, Sandra Díaz-Sánchez, Olga García-Álvarez, Rubén Fernández-Melgar, Marinela Contreras   +6 more
doaj   +1 more source

Antigenic identity of immunodominant proteins of Bacillus anthracis genovariants

Журнал микробиологии, эпидемиологии и иммунобиологии, 2023
Introduction. The main biological raw materials for the production of immunobiological preparations for identification of Bacillus anthracis are its specific antigens, the protective antigen and the EA1 protein. Purpose.
Margarita P. Izhberdeeva, Anastasiya A. Sautkina, Irina A. Barkova, Dmitry V. Viktorov   +3 more
doaj   +1 more source

Binding Sites of Anti-Lcr V Monoclonal Antibodies Are More Critical than the Avidities and Affinities for Passive Protection against Yersinia pestis Infection in a Bubonic Plague Model

Antibodies, 2020
Plague is a zoonotic disease that is caused by Yersinia pestis. Monoclonal antibodies (mAbs) that bind to the V-antigen, a virulence factor that is produced by Y. pestis, can passively protect mice from plague. An analysis of protective mAbs that bind to
Kei Amemiya, Jennifer L. Dankmeyer, Sarah L. Keasey, Sylvia R. Trevino, Michael M. Wormald, Stephanie A. Halasohoris, Wilson J. Ribot, David P. Fetterer, Christopher K. Cote, Patricia L. Worsham, Jeffrey J. Adamovicz, Robert G. Ulrich   +11 more
doaj   +1 more source

Current understanding of Bacillus anthracis toxin molecules organization and approaches for blocking their cytotoxic action

Инфекция и иммунитет, 2020
Here, we review the data on mechanisms inhibiting cytotoxic effect of anthrax toxin on the immune system cells. Various disease forms, immunopathogenesis and contemporary methods for anthrax treatment are discussed.
V. V. Firstova, I. G. Shemyakin, I. A. Dyatlov   +2 more
doaj   +1 more source

Human monoclonal anti-protective antigen antibody for the low-dose post-exposure prophylaxis and treatment of Anthrax. [PDF]

BMC Infect Dis, 2018
Tang Q, Xiong S, Liang X, Kuai X, Wang Y, Wang C, Feng Z, Zhu J.   +7 more
europepmc   +3 more sources

Genetic Construction of Bacillus subtilis Recombinant Strain, Producing Protective Antigen of Anthrax Microbe

Вестник войск РХБ защиты, 2023
Anthrax is a serious infectious disease with high mortality. The epidemiological security depends on the vaccination of susceptible animals and population at risk.
N. V. Onuchina, A. V. Kuznetsovsky, A. A. Vorobyov, A. V. Filippov   +3 more
doaj   +1 more source

Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications

Microorganisms, 2020
Anthrax toxins are produced by Bacillus anthracis throughout infection and shape the physiopathogenesis of the disease. They are produced in low quantities but are highly efficient.
Jean-Nicolas Tournier, Clémence Rougeaux   +1 more
doaj   +1 more source

Immunotropic and Immunogenic Properties of Nonspecific Yersinia Porins

Вестник войск РХБ защиты, 2023
The purpose of the study is to summarize our own data and literature data on the significance of poreforming proteins of the outer membrane of Yersinia as factors of their pathogenicity and as diagnostic and protective antigens, and their role in ...
O. D. Novikova, O. Yu. Portnyagina, O. P. Vostrikova, V. A. Ivanis   +3 more
doaj   +1 more source

Avidity of influenza-specific memory CD8+ T-cell populations decays over time compromising antiviral immunity [PDF]

, 2012
Decline of cell-mediated immunity is often attributed to decaying T-cell numbers and their distribution in peripheral organs. This study examined the hypothesis that qualitative as well as quantitative changes contribute to the declining efficacy of CD8+
Alexander-Miller, Almeida, Appay, Berger, Betts, Bosselut, Cerundolo, Gallimore, Gorman, Hansen, Hollander, Homann, Jelley-Gibbs, Jenkins, Jones, Jones, Judge, Karrer, Kattan, Kedzierska, Kim, Kohlmeier, Lefranc, Liang, Moffat, Neveu, Norbury, Powell, Price, Quigley, Rangel-Moreno, Richards, Roberts, Schluns, Tan, Tough, Trautmann, Valkenburg, Valkenburg, Woodland, Wooldridge, Zammit   +41 more
core   +1 more source