Results 31 to 40 of about 469,365 (378)
Vaccinal Preventon of Anthrax in the Russian Federation and Its Immediate Prospects
The purpose of the work is to show the possibilities of vaccine prophylaxis of anthrax in the Russian Federation and its immediate prospects. The article is dedicated to the vaccine preparations, available in Russia and abroad in the arsenal of medical ...
A. N. Shevtsov+3 more
doaj +1 more source
Recombinant anticoccidial vaccines - a cup half full? [PDF]
Eimeria species parasites can cause the disease coccidiosis, most notably in chickens. The occurrence of coccidiosis is currently controlled through a combination of good husbandry, chemoprophylaxis and/or live parasite vaccination; however, scalable ...
Ahmad+119 more
core +1 more source
Anthrax Vaccine Adsorbed (AVA) generates short-lived protective antigen (PA) specific IgG that correlates with in vitro toxin neutralization and protection from Bacillus anthracis challenge.
Lori Garman+5 more
doaj +1 more source
Vaccines against toxoplasma gondii : challenges and opportunities [PDF]
Development of vaccines against Toxoplasma gondii infection in humans is of high priority, given the high burden of disease in some areas of the world like South America, and the lack of effective drugs with few adverse effects.
Aliberti J+117 more
core +3 more sources
VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines [PDF]
Vaccine development in the post-genomic era often begins with the in silico screening of genome information, with the most probable protective antigens being predicted rather than requiring causative microorganisms to be grown. Despite the obvious advantages of this approach--such as speed and cost efficiency--its success remains dependent on the ...
Irini Doytchinova, Darren R. Flower
openaire +5 more sources
: Prompt and accurate detection of Bacillus anthracis spores is crucial in the event of intentional spore dissemination in order to reduce the number of expected casualties.
Efi Makdasi+5 more
doaj +1 more source
Expression and refolding of the protective antigen of Bacillus anthracis: A model for high-throughput screening of antigenic recombinant protein refolding [PDF]
Bacillus anthracis protective antigen (PA) is a well known and relevant immunogenicprotein that is the basis for both anthrax vaccines and diagnostic methods. Properly foldedantigenic PA is necessary for these applications.
Cairo, Fabian Martin+3 more
core +1 more source
Molecular tug of war reveals adaptive potential of an immune cell repertoire [PDF]
The adaptive immune system constantly remodels its lymphocyte repertoire for better protection against future pathogens. Its ability to improve antigen recognition on the fly relies on somatic mutation and selective expansion of B lymphocytes expressing high-affinity antigen receptors.
arxiv
A graph model for the evolution of specificity in humoral immunity [PDF]
The immune system protects the body against health-threatening entities, known as antigens, through very complex interactions involving the antigens and the system's own entities. One remarkable feature resulting from such interactions is the immune system's ability to improve its capability to fight antigens commonly found in the individual's ...
arxiv +1 more source
Computational model for tumor response to adoptive cell transfer therapy [PDF]
One of the barriers to the development of effective adoptive cell transfer therapies (ACT), specifically for genetically engineered T-cell receptors (TCRs), and chimeric antigen receptor (CAR) T-cells, is target antigen heterogeneity. It is thought that intratumor heterogeneity is one of the leading determinants of therapeutic resistance and treatment ...
arxiv