Results 51 to 60 of about 469,365 (378)
Improving the identification of antigenic sites in the H1N1 Influenza virus through accounting for the experimental structure in a sparse hierarchical Bayesian model [PDF]
J. R. Stat. Soc. C (2019), 2017 Understanding how genetic changes allow emerging virus strains to escape the protection afforded by vaccination is vital for the maintenance of effective vaccines. In the current work, we use structural and phylogenetic differences between pairs of virus strains to identify important antigenic sites on the surface of the influenza A(H1N1) virus through
arxiv +1 more source
Frontiers in Immunology, 2017 With many protective vaccine antigens reported in the literature and verified experimentally, how to use the knowledge mined from these antigens to support rational vaccine design and study underlying design mechanism remains unclear. In order to address
Edison Ong +3 more
doaj +1 more source
Comparative analysis of the immune responses induced by native versus recombinant versions of the ASP-based vaccine against the bovine intestinal parasite Cooperia oncophora [PDF]
, 2018 The protective capacities of a native double-domain activation-associated secreted protein (ndd-ASP)-based vaccine against the cattle intestinal nematode Cooperia oncophora has previously been demonstrated.
Borloo, Jimmy +6 more
core +1 more source
Frontiers in Microbiology, 2015 Brucellosis is one of the most common zoonoses worldwide. Subunit vaccines are promising for the prevention of human brucellosis. In our previous protective antigen screening studies, we identified a new protective antigen, BMEI0357, which belongs to the
Xinhui eWang +17 more
doaj +1 more source
The Role of Russian Scientists in the Development of Anthrax Vaccines
Aktualʹnaâ Infektologiâ, 2015 In Russia in the second half of the XIX century, research schools developing anthrax vaccines for agriculture were formed. According to their level, they are not inferior to similar Western schools.
M.V. Supotnytskyi +5 more
doaj +1 more source
Securing of Unmanned Aerial Systems (UAS) against security threats using human immune system [PDF]
Reliability Engineering & System Safety, 193, 106675 (2020), 2020 UASs form a large part of the fighting ability of the advanced military forces. In particular, these systems that carry confidential information are subject to security attacks. Accordingly, an Intrusion Detection System (IDS) has been proposed in the proposed design to protect against the security problems using the human immune system (HIS). The IDSs
arxiv +1 more source
Toxins, 2015 The principal portal for anthrax infection in natural animal outbreaks is the digestive tract. Enteric exposure to anthrax, which is difficult to detect or prevent in a timely manner, could be exploited as an act of terror through contamination of human ...
Bruce Huang +4 more
doaj +1 more source
Toxins, 2017 The anthrax lethal toxin consists of protective antigen (PA) and lethal factor (LF). Understanding both the PA pore formation and LF translocation through the PA pore is crucial to mitigating and perhaps preventing anthrax disease.
Alexandra J. Machen +10 more
doaj +1 more source
Antibodies to glycans dominate the host response to schistosome larvae and eggs: Is their role protective or subversive? [PDF]
, 2001 Multiple exposures of chimpanzees to the radiation-attenuated schistosome vaccine provoked a strong parasite-specific cellular and humoral immune response. Specific IgM and IgG were directed mainly against glycans on antigens released by cercariae; these
Coulson, P.S. +7 more
core +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source