Results 91 to 100 of about 1,542 (164)

IN-SILICO IDENTIFICATION OF POTENTIAL PROTEIN ARGININE DEIMINASE IV (PAD4) INHIBITORS

Malaysian Journal of Analytical Science, 2016
Protein Arginine Deiminase IV (PAD4) is a promising target for treating rheumatoid arthritis. Here, an in-silico screening was performed using PAD4 crystal structure against National Cancer Institute Diversity Set III compounds. Results obtained from the docking studies showed that the compounds have high affinity towards the protein.
openaire   +1 more source

Protein-Arginine Deiminase Type-2 [PDF]

, 2020
openaire   +1 more source

[Protein arginine deiminase of oral microbiome plays a causal role in the polyarthritis rheumatoid initiating].

Medecine sciences : M/S, 2020
In the last decade, the association between the periodontitis and rheumatoid arthritis (RA) has been established, suggesting that oral microbiome plays a causal role by initiating this chronic autoimmune inflammatory disease of articulation. Both pathogenesis are similar in term of chronic inflammation, tissue breakdown and bone resorption.
Desclos-Theveniau, Marie, Bonnaure-Mallet, Martine, Meuric, Vincent   +2 more
openaire   +2 more sources

Protein-Arginine Deiminase Type-4 [PDF]

, 2020
openaire   +1 more source

Targeting Peptidylarginine Deiminases in Neurons and Astrocytes in Central Nervous System Injury-Effects of Pan-PAD Inhibitor Cl-Amidine in an Oxygen-Glucose Deprivation Model of Ischaemia (OGD/R) and LPS Stimulation In Vitro. [PDF]

Int J Mol Sci
Ahmed D, Getting SJ, Ashioti M, Lange S.
europepmc   +1 more source

Inhibition of <italic>Pseudomonas aeruginosa</italic> Biofilm Formation by Peptidyl-Arginine Deiminases 2 and 4. [PDF]

J Innate Immun
Baird R, Gogoi D, Forde L, Ahmed SW, Niu M, Cavanagh B, Fitzpatrick F, Reeves EP.   +7 more
europepmc   +1 more source

Inhibition of PADI2-mediated vimentin citrullination alleviates silica-induced pulmonary fibrosis in mice. [PDF]

Part Fibre Toxicol
Jin F, Li Y, Li T, Liu S, Xu D, Liu H, Wei Z, Gao X, Mao N, Cai W, Shi Y, Zhang H, Xu H.   +12 more
europepmc   +1 more source

Peptidylarginine Deiminases: An Overview of Recent Advances in Citrullination Research. [PDF]

Int J Mol Sci
Kijak-Boćkowska M, Czerwińska J, Owczarczyk-Saczonek A.   +2 more
europepmc   +1 more source

Novel Biomarker for Rheumatoid Arthritis: Serum Peptidylarginine Deiminase 4-Potentiating Activity in an Anti-Citrullinated Protein Antibody-Positive At-Risk Population. [PDF]

Scand J Immunol
Kaminska M, Joshua V, Bielecka E, Kantyka T, Chrobak M, Lundberg K, Hensvold A, Potempa J, Mydel P.   +8 more
europepmc   +1 more source

Beyond PAD Inhibition: Emerging Avenues and Natural Products for Targeting Citrullination in Immune Diseases. [PDF]

Biomedicines
Chen Q, Ma Y, Liu Y, Wang X, Huang G, Yang Y, Ko JK, Chen H.   +7 more
europepmc   +1 more source