Results 131 to 140 of about 1,542 (164)

Amino Acid Metabolism of the Skin: Control by Specific Enzymes and Contribution to Protective Functions. [PDF]

Metabolites
Dörner C, Steinbinder J, Sachslehner AP, Sukseree S, Eckhart L.   +4 more
europepmc   +1 more source

Cardiac PAD2 expression and myocardial citrullination decline with age in female mice independent of estrogen. [PDF]

Am J Physiol Heart Circ Physiol
Shorthill SK, Klinger FR, Yusifov A, Thornburg JP, Schmitt MP, Mehl ER, Bettadapura SS, Agor MH, Teulé-Finley F, Cherrington BD, Bruns DR.   +10 more
europepmc   +1 more source

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review). [PDF]

Int J Oncol
Ni X, Zhang M, Zhang K, Wang C, Guo J, Fan W, Zheng L, Jiang T, Zhang G.   +8 more
europepmc   +1 more source

Arginine: at the crossroads of nitrogen metabolism. [PDF]

EMBO J
Fung TS, Ryu KW, Thompson CB.
europepmc   +1 more source

The protein arginine deiminases: Structure, function, inhibition, and disease [PDF]

Biopolymers, 2013
AbstractThe post‐translational modification of histones has significant effects on overall chromatin function. One such modification is citrullination, which is catalyzed by the protein arginine deiminases (PADs), a unique family of enzymes that catalyzes the hydrolysis of peptidyl‐arginine to form peptidyl‐citrulline on histones, fibrinogen, and other
Kevin L Bicker, Paul R Thompson
exaly   +6 more sources

Inhibiting Protein Arginine Deiminases Has Antioxidant Consequences [PDF]

Journal of Pharmacology and Experimental Therapeutics, 2015
Ulcerative colitis is a dynamic, idiopathic, chronic inflammatory condition that carries a high colon cancer risk. We previously showed that Cl-amidine, a small-molecule inhibitor of the protein arginine deiminases, suppresses colitis in mice. Because colitis is defined as inflammation of the colon associated with infiltration of white blood cells that
Xiangli Cui, Anne B Hofseth, Venkataraman Subramanian   +2 more
exaly   +7 more sources

Protein Arginine Deiminases (PADs): Biochemistry and Chemical Biology of Protein Citrullination [PDF]

Accounts of Chemical Research, 2019
Proteins are well-known to undergo a variety of post-translational modifications (PTMs). One such PTM is citrullination, an arginine modification that is catalyzed by a group of hydrolases called protein arginine deiminases (PADs). Hundreds of proteins are known to be citrullinated and hypercitrullination is associated with autoimmune diseases ...
Santanu Mondal, Paul R Thompson
exaly   +6 more sources

Chemical biology of protein citrullination by the protein A arginine deiminases [PDF]

Current Opinion in Chemical Biology, 2021
Santanu Mondal, Paul R Thompson
exaly   +2 more sources

The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs) [PDF]

ACS Chemical Biology, 2018
Venkaṭesh V Nemmara, Venkataraman Subramanian, Aaron Muth   +2 more
exaly   +2 more sources

Interrogation of the Active Sites of Protein Arginine Deiminases (PAD1, -2, and -4) Using Designer Probes [PDF]

ACS Medicinal Chemistry Letters, 2013
Lianhu Wei, Mario A Moscarello, Lakshmi P Kotra   +2 more
exaly   +2 more sources