Results 151 to 160 of about 3,416,691 (229)

IN-SILICO IDENTIFICATION OF POTENTIAL PROTEIN ARGININE DEIMINASE IV (PAD4) INHIBITORS

Malaysian Journal of Analytical Science, 2016
Protein Arginine Deiminase IV (PAD4) is a promising target for treating rheumatoid arthritis. Here, an in-silico screening was performed using PAD4 crystal structure against National Cancer Institute Diversity Set III compounds. Results obtained from the docking studies showed that the compounds have high affinity towards the protein.
openaire   +1 more source

OP0118 DECIPHERING THE ANTI-PROTEIN-ARGININE DEIMINASE (PAD) RESPONSE IDENTIFIES PAD1 AND PAD6 AS NOVEL AUTOANTIGENS IN RHEUMATOID ARTHRITIS [PDF]

, 2020
Laura Martínez-Prat, Mary Ann Aure, Chelsea Bentow, David Lucia, Marcos López‐Hoyos, Michael Mähler   +5 more
openalex   +1 more source

Targeted delivery of protein arginine deiminase-4 inhibitors to limit arterial intimal NETosis and preserve endothelial integrity

, 2021
Roberto Molinaro, Mikyung Yu, Grasiele Sausen, Colette Andrea Bichsel, Claudia Corbo, Eduardo J.E. Folco, Gha Young Lee, Yuan Liu, Yevgenia Tesmenitsky, Eugenia Shvartz, Galina K. Sukhova, Frederik Kloss, Kevin Croce, Omid Cameron Farokhzad, Jinjun Shi, Peter Libby   +15 more
openalex   +2 more sources

The twin arginine translocation pathway in Escherichia coli : mechanism and quality control [PDF]

The bacterial twin-arginine translocation (Tat) pathway has the unique ability to export pre-folded proteins across the cytoplasmic membrane. Its name came from the almost invariant twin-arginine motif in the signal peptide of Tat substrates ...
Ren, Chao, Ph.D.
core  

Differential histone tail citrullination by protein arginine deiminases observed via NMR spectroscopy

Alex J Kowalczyk, Emma A. Morrison
openalex   +1 more source

Organisation and mechanism of bacterial twin arginine translocases [PDF]

The bacterial Tat pathway facilitates the translocation of pre-folded proteins over the cytoplasmic membrane. In Gram-negative bacteria, TatA, TatB and TatC (each an integral membrane protein) are the essential components.
Barnett, James Paul
core  

Protein Citrullination by Peptidyl Arginine Deiminase/Arginine Deiminase Homologs in Members of the Human Microbiota and Its Recognition by Anti-Citrullinated Protein Antibodies

María Elena Pérez-Pérez, Enrique Nieto-Torres, Juan José Bollain-y-Goytia, Lucia Delgadillo-Ruíz   +3 more
openalex   +1 more source

Neutrophil Extracellular Trap Formation-Derived Peptidylarginine Deiminases in the Citrullination of Oral Bacteria to Promote Inflammation in Rheumatoid Arthritis. [PDF]

J Rheumatol
Acharya S, Brewer RC, Gomez AM, Younis S, Pandit M, Jahanbani S, Sharpe O, Love ZZ, Howard MC, Orange DE, Robinson WH.   +10 more
europepmc   +1 more source

Fusion Proteins in the Fight against Colorectal Cancer: Assessing the Cytotoxic Potential of Recombinant Nisin-Arginine Deiminase Fusion Protein

Bahareh Hajikhani, Naghmeh Boyaghchi, Samin Mirhosseini, Mehdi Goudarzi, Hossein Goudarzi, Fatemeh Sameni, Masoud Dadashi   +6 more
openalex   +1 more source

Design and Production of Arginine Deiminase-Azurin Recombinant Fusion Protein from Pseudomonas aeruginosa and its Confirmation by Western Blot

, 2020
Muhammad N.S. Hadi, Mona Ghazi, Parvaneh Saffarian, Bahareh Hajikhani   +3 more
openalex   +2 more sources