Results 141 to 150 of about 3,416,691 (229)

Peptidylarginine deiminases (PADs): novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates

, 2014
Neonatal hypoxic ischaemic (HI) injury frequently causes neural impairment in surviving infants. Our knowledge of the underlying molecular mechanisms is still limited.
Raivich, G., Lange, S., Hristova, M., Peebles, D., Thompson, P.R., Nicholas, A.P., Mawjee, P., Rocha-Ferreira, E., Thei, L.   +8 more
core   +1 more source

Interrogation of the Active Sites of Protein Arginine Deiminases (PAD1, -2, and -4) Using Designer Probes

, 2016
Protein arginine deiminases (PADs) are involved in a number of cellular pathways, and they catalyze the transformation of peptidyl arginine residue into a citrulline as part of post-translational modifications.
Ewa Wasilewski (1976233), Mario A. Moscarello (1993210), Lianhu Wei (1278753), Angelica M. Bello (1976227), Lakshmi P. Kotra (1278741)   +4 more
core   +1 more source

Development of inhibitors of Arginine Deiminases

There are over 650 posttranslational modifications (PTM) that help regulate cellular function. One such modification is called citrullination, or deimination.
Balukonis, Lauren
core   +3 more sources

Combination of Two Monoclonal Anti–Citrullinated Protein Antibodies Induced Tenosynovitis, Pain, and Bone Loss in Mice in a Peptidyl Arginine Deiminase‐4–Dependent Manner

, 2022
Akilan Krishnamurthy, Alexandra Cîrciumaru, Jitong Sun, Yogan Kisten, Peter Damberg, Koji Sakuraba, Katalin Sándor, Patrik Jarvoll, Tunhe Zhou, Vivianne Malmström, Camilla I. Svensson, Aase Haj Hensvold, Anca I. Catrina, Lars Klareskog, Bence Réthi   +14 more
openalex   +1 more source

Characterizations of Protein Arginine Deiminase 1 as a Substrate of NTMT1: Implications of Nα-Methylation in Protein Stability and Interaction [PDF]

Ying Meng, Zhouxian Li, Ming He, Quanqing Zhang, Youchao Deng, Yinsheng Wang, Rong Huang   +6 more
openalex   +1 more source

Additional file 4 of Protein arginine deiminase 2 (PAD2) modulates the polarization of THP-1 macrophages to the anti-inflammatory M2 phenotype

, 2022
Aneta Stachowicz, Rakhi Pandey, Niveda Sundararaman, Vidya Venkatraman, Jennifer E. Van Eyk, Justyna Fert‐Bober   +5 more
openalex   +1 more source

Additional file 2 of Protein arginine deiminase 2 (PAD2) modulates the polarization of THP-1 macrophages to the anti-inflammatory M2 phenotype

, 2022
Aneta Stachowicz, Rakhi Pandey, Niveda Sundararaman, Vidya Venkatraman, Jennifer E. Van Eyk, Justyna Fert‐Bober   +5 more
openalex   +1 more source

The clinical and prognostic significance of Protein Arginine Deiminase 2 and 4 (PADI2 & PADI4) in colorectal cancer [PDF]

, 2020
Mohamed Gijon, Rachael L. Metheringham, Michael S. Toss, Samantha J. Paston, Lindy G. Durrant   +4 more
openalex   +1 more source

Additional file 3 of Protein arginine deiminase 2 (PAD2) modulates the polarization of THP-1 macrophages to the anti-inflammatory M2 phenotype

, 2022
Aneta Stachowicz, Rakhi Pandey, Niveda Sundararaman, Vidya Venkatraman, Jennifer E. Van Eyk, Justyna Fert‐Bober   +5 more
openalex   +1 more source

Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation [PDF]

, 2020
Qingfei Zheng, Adewola Osunsade, Yael David   +2 more
openalex   +1 more source