Results 41 to 50 of about 12,507,251 (357)

Structure of cyanobacterial photosystem I complexed with ferredoxin at 1.97 Å resolution

Communications Biology, 2022
In order to aid the understanding of the electron transfer process within the cyanobacterial photosystem I, its structure - when complexed with Ferredoxin - is determined at 1.97 Å resolution.
Jiannan Li, Noriyuki Hamaoka, Fumiaki Makino, Akihiro Kawamoto, Yuxi Lin, Matthias Rögner, Marc M. Nowaczyk, Young-Ho Lee, Keiichi Namba, Christoph Gerle, Genji Kurisu   +10 more
doaj   +1 more source

Predicting Antibody Developability Profiles Through Early Stage Discovery Screening

mAbs, 2020
Monoclonal antibodies play an increasingly important role for the development of new drugs across multiple therapy areas. The term ‘developability’ encompasses the feasibility of molecules to successfully progress from discovery to development via ...
Marc Bailly, Carl Mieczkowski, Veronica Juan, Essam Metwally, Daniela Tomazela, Jeanne Baker, Makiko Uchida, Ester Kofman, Fahimeh Raoufi, Soha Motlagh, Yao Yu, Jihea Park, Smita Raghava, John Welsh, Michael Rauscher, Gopalan Raghunathan, Mark Hsieh, Yi-Ling Chen, Hang Thu Nguyen, Nhung Nguyen, Dan Cipriano, Laurence Fayadat-Dilman   +21 more
doaj   +1 more source

Galectins use N-glycans of FGFs to capture growth factors at the cell surface and fine-tune their signaling

Cell Communication and Signaling, 2023
Fibroblast growth factors (FGFs) and their receptors (FGFRs) constitute complex signaling hubs that are crucial for the development and homeostasis of the human body.
Aleksandra Gedaj, Dominika Zukowska, Natalia Porebska, Marta Pozniak, Mateusz Krzyscik, Aleksandra Czyrek, Daniel Krowarsch, Malgorzata Zakrzewska, Jacek Otlewski, Lukasz Opalinski   +9 more
doaj   +1 more source

Green protein from locally grown crops (OK-Net EcoFeed Practice Abstract) [PDF]

, 2020
• Choose an appropriate type of green crop, such as clover-grass or alfalfa, with an expected high protein and amino acid content. Consider soil types and weather patterns to grow a crop with a good and high quality yield. • Harvest the field at regular
Ambye-Jensen, Morten, Lübeck, Mette, Steenfeldt, Sanna   +2 more
core  

Mitochondrial protein import [PDF]

, 1994
The transport of nuclear-encoded proteins from the cytosol into mitochondria is mediated by targeting (signal) sequences present on precursor forms.
Neupert, Walter, Schwarz, Elisabeth
core   +1 more source

Dataset concerning GroEL chaperonin interaction with proteins

Data in Brief, 2016
GroEL chaperonin is well-known to interact with a wide variety of polypeptide chains. Here we show the data related to our previous work (http://dx.doi.org/10.1016/j.pep.2015.11.020 [1]), and concerning the interaction of GroEL with native (lysozyme, α ...
V.V. Marchenkov, N.Yu. Marchenko, A.L. Kaysheva, N.V. Kotova, I.A. Kashparov, G.V. Semisotnov   +5 more
doaj   +1 more source

Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins

Nature Communications, 2021
RaPID (Random non-standard Peptides Integrated Discovery) enables discovery of small macrocyclic peptides binding desired targets. Here, the authors propose lasso-grafting: the RaPID-derived peptides are implanted onto diverse proteins and maintain both ...
Emiko Mihara, Satoshi Watanabe, Nasir K. Bashiruddin, Nozomi Nakamura, Kyoko Matoba, Yumi Sano, Rumit Maini, Yizhen Yin, Katsuya Sakai, Takao Arimori, Kunio Matsumoto, Hiroaki Suga, Junichi Takagi   +12 more
doaj   +1 more source

Sequence-specific protein aggregation generates defined protein knockdowns in plants [PDF]

, 2016
Protein aggregation is determined by short (5-15 amino acids) aggregation-prone regions (APRs) of the polypeptide sequence that self-associate in a specific manner to form beta-structured inclusions.
Aesaert, Stijn, Betti, Camilla, Coutuer, Silvie, De Rycke, Riet, De Smet, Frederik, Gallardo, Rodrigo, Inzé, Dirk, Mishev, Kiril, Rombaut, Debbie, Rousseau, Frederic, Russinova, Eugenia, Schymkowitz, Joost, Van Breusegem, Frank, Van Lijsebettens, Maria, Vanhoutte, Isabelle, Vuylsteke, Marnik, Xu, Jie   +16 more
core   +2 more sources

Near-Wall Aggregation of Amyloidogenic Aβ 1-40 Peptide: Direct Observation by the FRET

Molecules, 2021
The formation of amyloid fibrils is one of the variants of the self-organization of polypeptide chains. For the amyloid aggregation, the solution must be oversaturated with proteins.
Natalia Katina, Alisa Mikhaylina, Nelly Ilina, Irina Eliseeva, Vitalii Balobanov   +4 more
doaj   +1 more source

Side-chain conformational changes upon protein-protein association [PDF]

, 2010
Conformational changes upon protein-protein association are the key element of the binding mechanism. The study presents a systematic large-scale analysis of such conformational changes in the side chains.
Kirys, Tatsiana, Ruvinsky, Anatoly M., Tuzikov, Alexander V., Vakser, Ilya A.   +3 more
core   +2 more sources