Results 41 to 50 of about 15,507,347 (338)
A new census of protein tandem repeats and their relationship with intrinsic disorder [PDF]
Protein tandem repeats (TRs) are often associated with immunity-related functions and diseases. Since that last census of protein TRs in 1999, the number of curated proteins increased more than seven-fold and new TR prediction methods were published. TRs
Anisimova, Maria+4 more
core +1 more source
We are proud to present the first edition of the Protein–protein interactions Section of Current Opinion in Structural Biology. The Section is new, but the topic has been present in the journal from the very start. Volume 1, Issue 1, dated February 1991, had a review by Janin entitled Protein–protein interactions and assembly, and others by Bode and ...
Joël Janin, Alexandre M. J. J. Bonvin
openaire +4 more sources
Statistical characterization of therapeutic protein modifications
Peptide mapping with liquid chromatography–tandem mass spectrometry (LC-MS/MS) is an important analytical method for characterization of post-translational and chemical modifications in therapeutic proteins.
Tsung-Heng Tsai+13 more
doaj +1 more source
The development of many severe human diseases is associated with the formation of amyloid fibrils. Most of the available information on the process of amyloid formation has been obtained from studies of small proteins and peptides, wherein the features ...
Victor Marchenkov+5 more
doaj +1 more source
Minimum energy configurations of the 2-dimensional HP-model of proteins by self-organizing networks [PDF]
We use self-organizing maps (SOM) as an efficient tool to find the minimum energy configurations of the 2-dimensional HP-models of proteins. The usage of the SOM for the protein folding problem is similar to that for the Traveling Salesman Problem.
Erman, Burak+2 more
core +1 more source
Influence of mutations of Val226 on the catalytic rate of haloalkane dehalogenase [PDF]
Haloalkane dehalogenase converts haloalkanes to their corresponding alcohols. The 3D structure, reaction mechanism and kinetic mechanism have been studied.
Janssen, Dick B.,+3 more
core +2 more sources
SWISS-MODEL: homology modelling of protein structures and complexes
Homology modelling has matured into an important technique in structural biology, significantly contributing to narrowing the gap between known protein sequences and experimentally determined structures. Fully automated workflows and servers simplify and
A. Waterhouse+11 more
semanticscholar +1 more source
Computationally designed variants of Escherichia coli chorismate mutase show altered catalytic activity [PDF]
Computational protein design methods were used to predict five variants of monofunctional Escherichia coli chorismate mutase expected to maintain catalytic activity.
Keeffe, Jennifer R.+3 more
core +2 more sources
Bacteriophage Protein–Protein Interactions [PDF]
Bacteriophages T7, λ, P22, and P2/P4 (from Escherichia coli), as well as ϕ29 (from Bacillus subtilis), are among the best-studied bacterial viruses. This chapter summarizes published protein interaction data of intraviral protein interactions, as well as known phage-host protein interactions of these phages retrieved from the literature. We also review
Roman Häuser+9 more
openaire +5 more sources
A system-wide understanding of cellular function requires knowledge of all functional interactions between the expressed proteins. The STRING database aims to collect and integrate this information, by consolidating known and predicted protein–protein ...
Damian Szklarczyk+11 more
semanticscholar +1 more source