Results 131 to 140 of about 486,105 (348)

Mesoscale fractal whey protein particles derived from microscale linear-shaped protein assemblies (Part 2): Foaming properties and heat stability

Journal of Dairy Science
: This study investigates the functionality of mesoscale whey protein particles (WPP) derived from fiber- and ribbon-shaped whey protein assemblies produced via a liquid antisolvent precipitation-based method.
Hanyu Shi, Haotian Zheng
doaj   +1 more source

Spatial Sequestration and Oligomer Remodeling During \u3cem\u3ede novo\u3c/em\u3e [\u3cem\u3ePSI\u3c/em\u3e\u3csup\u3e+\u3c/sup\u3e] Formation [PDF]

, 2017
Prions are misfolded, aggregated, infectious proteins found in a range of organisms from mammals to bacteria. In mammals, prion formation is difficult to study because misfolding and aggregation take place prior to symptom presentation.
Lyke, Douglas, Manogaran, Anita L.
core   +1 more source

The proteostasis network and its decline in ageing

, 2019
Ageing is a major risk factor for the development of many diseases, prominently including neurodegenerative disorders such as Alzheimer disease and Parkinson disease.
Hartl, F., Hipp, M., Kasturi, P.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Protein adsorption onto Fe3O4 nanoparticles with opposite surface charge and its impact on cell uptake

, 2014
Nanoparticles (NPs) engineered for biomedical applications are meant to be in contact with protein-rich physiological fluids. These proteins are usually adsorbed onto the NP surface, forming a swaddling layer called protein corona that influences cell ...
Catalayud, M. P., Goya, G. F., Ibarra, M. R., Raffa, V., Riggio, C., Sanz, B.   +5 more
core   +1 more source

Effects of ultrasound on the structural and emulsifying properties and interfacial properties of oxidized soybean protein aggregates

, 2022
Yi-Chang Wang, Bailiang Li, Yanan Guo, Caihua Liu, Jun Liu, Bin Tan, Zengwang Guo, Zhongjiang Wang, Lianzhou Jiang   +8 more
openalex   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Aggregability and digestibility study of fruit juice fortified camel milk powder proteins

, 2021
K. S. Urmila, Sami Ghnimi, Nikola Stevanović, Andreja Rajković, Tanja Ćirković Veličković   +4 more
openalex   +2 more sources

PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates [PDF]

, 2021
Hong-Wei Yue, Jun-Ye Hong, Shuxian Zhang, Leilei Jiang, Hong‐Yu Hu   +4 more
openalex   +1 more source