Immunosuppressive Cytokine‐Tethered Hydrogel for Treating Rheumatoid Arthritis
An injectable hydrogel is developed by chemically tethering IL‐4, an immunosuppressive cytokine, to a hyaluronic acid‐based backbone. The hydrogel reduces joint friction and exerts immunomodulatory effects. In a rheumatoid arthritis (RA) mouse model, it reduced inflammation, preserved cartilage, and promoted anti‐inflammatory immune responses.
Woojin Back+3 more
wiley +1 more source
High‐Resolution Patterned Delivery of Chemical Signals From 3D‐Printed Picoliter Droplet Networks
3D‐printed picoliter droplet networks have been fabricated that control gene expression in bacterial populations by releasing chemical signals with precise spatial definition and high temporal resolution. This system of effector release is widely applicable, offering diverse applications in biology and medicine.
Jorin Riexinger+7 more
wiley +1 more source
Analytical Performance of a Venturi-Assisted Array of Micromachined Ultrasonic Electrosprays Coupled to Ion Trap Mass Spectrometry for the Analysis of Peptides and Proteins [PDF]
Christina Y. Hampton+6 more
openalex +1 more source
T-cell responses to highly conserved SARS-CoV-2 epitopes in Hispanic Americans receiving an mRNA COVID-19 vaccine. [PDF]
Haltaufderhyde K+6 more
europepmc +1 more source
Supramolecular Chemistry in Metal–Organic Framework Materials
This review highlights synergies between reticular chemistry and supramolecular chemistry. The role of supramolecular interactions in determining framework…guest interactions and attempts to understand dynamic behavior in metal–organic frameworks (MOFs), particularly emphasizing the development of crystal sponges, studying reactions in frameworks and ...
Eugenia Miguel‐Casañ+3 more
wiley +1 more source
TIGR-Tas: A family of modular RNA-guided DNA-targeting systems in prokaryotes and their viruses. [PDF]
Faure G+12 more
europepmc +1 more source
Electronic biosensor arrays for label-free DNA and protein analysis
Claudio, Stagni degli Esposti
openaire +2 more sources
Retrospective Review on Reticular Materials: Facts and Figures Over the Last 30 Years
To shape the future course of research in reticular materials, this work reflects on the progress over the past 30 years, complemented by input from the community of 228 active researchers through a global, crowdsourced survey: ranging from demographics, how it works, publish and interact, to highlights on both academic and industrial milestones, as ...
Aamod V. Desai+8 more
wiley +1 more source
A motif-based analysis of glycan array data to determine the specificities of glycan-binding proteins [PDF]
Andrew P. Porter+5 more
openalex +1 more source