Results 41 to 50 of about 2,014,238 (321)

A targeted antibody-based array reveals a serum protein signature as biomarker for adolescent idiopathic scoliosis patients

open access: yesBMC Genomics, 2023
Background Evident adolescent idiopathic scoliosis (AIS) incurs high treatment costs, low quality of life, and many complications. Early screening of AIS is essential to avoid progressing to an evident stage.
Zhenxuan Shao   +8 more
doaj   +1 more source

Membrane Array Analysis of Tear Proteins in Ocular Cicatricial Pemphigoid [PDF]

open access: yesOptometry and Vision Science, 2011
To explore non-invasive, protein-based, membrane array technology as a means to evaluate the global immune and angiogenic profile of tear proteins in patients with active ocular cicatricial pemphigoid (OCP).Forty-three proteins consisting of cytokines, angiogenic/growth factors, and immunoinflammatory modulators were measured by membrane array in tear ...
Matilda F, Chan   +8 more
openaire   +2 more sources

Specificity Analysis of Protein Lysine Methyltransferases Using SPOT Peptide Arrays [PDF]

open access: yesJournal of Visualized Experiments, 2014
Lysine methylation is an emerging post-translation modification and it has been identified on several histone and non-histone proteins, where it plays crucial roles in cell development and many diseases. Approximately 5,000 lysine methylation sites were identified on different proteins, which are set by few dozens of protein lysine methyltransferases ...
Srikanth, Kudithipudi   +3 more
openaire   +2 more sources

Predicting Deep Learning Based Multi-Omics Parallel Integration Survival Subtypes in Lung Cancer Using Reverse Phase Protein Array Data

open access: yesBiomolecules, 2020
Mortality attributed to lung cancer accounts for a large fraction of cancer deaths worldwide. With increasing mortality figures, the accurate prediction of prognosis has become essential.
Satoshi Takahashi   +11 more
semanticscholar   +1 more source

Reno: regularized non-parametric analysis of protein lysate array data [PDF]

open access: yesBioinformatics, 2012
Abstract Motivation: The reverse-phase protein lysate arrays have been used to quantify the relative expression levels of a protein in a number of cellular samples simultaneously. To avoid quantification bias due to mis-specification of commonly used parametric models, a nonparametric approach based on monotone response curves may be ...
Bin, Li   +3 more
openaire   +2 more sources

Application of mRNA Arrays for the Production of mCherry Reporter-Protein Arrays for Quantitative Gene Expression Analysis [PDF]

open access: yesACS Synthetic Biology, 2019
The development of programmable regulators that precisely and predictably control gene expression is a major goal of synthetic biology. Consequently, rapid high-throughput biochemical methods capable of quantitatively analyzing all components of gene expression would be of value in the characterization and optimization of regulator performance. In this
Masoud Norouzi   +4 more
openaire   +3 more sources

PMA: Protein Microarray Analyser, a user-friendly tool for data processing and normalization

open access: yesBMC Research Notes, 2018
Objective Protein microarrays provide a high-throughput platform to measure protein interactions and associated functions, and can aid in the discovery of cancer biomarkers.
Jessica Da Gama Duarte   +3 more
doaj   +1 more source

A Novel Method to Identify Autoantibodies against Putative Target Proteins in Serum from beta-Thalassemia Major: A Pilot Study

open access: yesBiomedicines, 2020
Abnormal immune reactivity in patients with beta-thalassemia (beta-thal) major can be associated with poor prognosis. Immunome protein-array analysis represents a powerful approach to identify novel biomarkers.
Afshan Sumera   +7 more
doaj   +1 more source

Monitoring of Serum Levels of Angiogenin, ENA-78 and GRO Chemokines in Patients with Renal Cell Carcinoma (RCC) in the Course of the Treatment

open access: yesActa Medica, 2008
Tumour progression requires the presence of a rich vascular supply. A number of cytokines, chemokines and proteases participate in the process of tumour angiogenesis.
Dagmar Hlávková   +8 more
doaj   +1 more source

YPIBP: A repository for phosphoinositide-binding proteins in yeast

open access: yesComputational and Structural Biotechnology Journal, 2021
Phosphoinositides (PIs) are a family of eight lipids consisting of phosphatidylinositol (PtdIns) and its seven phosphorylated forms. PIs have important regulatory functions in the cell including lipid signaling, protein transport, and membrane ...
Jagat Rathod   +5 more
doaj   +1 more source

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