Results 41 to 50 of about 559,282 (295)

PMA: Protein Microarray Analyser, a user-friendly tool for data processing and normalization

BMC Research Notes, 2018
Objective Protein microarrays provide a high-throughput platform to measure protein interactions and associated functions, and can aid in the discovery of cancer biomarkers.
Jessica Da Gama Duarte, Ryan W. Goosen, Peter J. Lawry, Jonathan M. Blackburn   +3 more
doaj   +1 more source

A Novel Method to Identify Autoantibodies against Putative Target Proteins in Serum from beta-Thalassemia Major: A Pilot Study

Biomedicines, 2020
Abnormal immune reactivity in patients with beta-thalassemia (beta-thal) major can be associated with poor prognosis. Immunome protein-array analysis represents a powerful approach to identify novel biomarkers.
Afshan Sumera, Nur Diana Anuar, Ammu Kutty Radhakrishnan, Hishamshah Ibrahim, Nurul H. Rutt, Nur Hafiza Ismail, Ti-Myen Tan, Abdul Aziz Baba   +7 more
doaj   +1 more source

Monitoring of Serum Levels of Angiogenin, ENA-78 and GRO Chemokines in Patients with Renal Cell Carcinoma (RCC) in the Course of the Treatment

Acta Medica, 2008
Tumour progression requires the presence of a rich vascular supply. A number of cytokines, chemokines and proteases participate in the process of tumour angiogenesis.
Dagmar Hlávková, Otakar Kopecký, Šárka Lukešová, Vladimíra Vroblová, Ctirad Andrýs, Petr Morávek, Miroslav Podhola, Doris Vokurková, Hynek Šafránek   +8 more
doaj   +1 more source

YPIBP: A repository for phosphoinositide-binding proteins in yeast

Computational and Structural Biotechnology Journal, 2021
Phosphoinositides (PIs) are a family of eight lipids consisting of phosphatidylinositol (PtdIns) and its seven phosphorylated forms. PIs have important regulatory functions in the cell including lipid signaling, protein transport, and membrane ...
Jagat Rathod, Han-Chen Yen, Biqing Liang, Yan-Yuan Tseng, Chien-Sheng Chen, Wei-Sheng Wu   +5 more
doaj   +1 more source

Proteomics, pathway array and signaling network-based medicine in cancer

Cell Division, 2009
Cancer is a multifaceted disease that results from dysregulated normal cellular signaling networks caused by genetic, genomic and epigenetic alterations at cell or tissue levels. Uncovering the underlying protein signaling network changes, including cell
Xu Hong, Liu Wei, Song Dong, Wu Josephine, Wang Libo, Wang Hongxia, Che Yufang, Zhao Xin, Liu Xiaoliang, Gao Ling, Ye Fei, Zhang David Y, Jiang Bo, Zhang Weijia, Wang Jinhua, Lee Peng   +15 more
doaj   +1 more source

Bioinformatics analysis of mitochondrial encephalomyopathy with lactic acidemia and stroke⁃like episodes geneome microarray based on GEO database

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To investigate the possible pathogenesis and clinical feature of mitochondrial encephalomyopathy with lactic acidemia and stroke ⁃ like episodes (MELAS) on the molecular level by bioinformatics analysis of differential expression genes. Methods
Qian XU, Yang GAO, Lei LI, Jun YAN, Li⁃ling WANG, Tao⁃jie REN   +5 more
doaj  

A Metabolomics Investigation of the Metabolic Changes of Raji B Lymphoma Cells Undergoing Apoptosis Induced by Zinc Ions

Metabolites, 2021
Zinc plays a pivotal role in the function of cells and can induce apoptosis in various cancer cells, including Raji B lymphoma. However, the metabolic mechanism of Zn-induced apoptosis in Raji cells has not been explored.
Naeun Yoon, Hyunbeom Lee, Geonhee Lee, Eun Hye Kim, Seong Hwan Kim, Jeong-O Lee, Yunseon Song, Jinyoung Park, So-Dam Kim, Yeojin Kim, Byung Hwa Jung   +10 more
doaj   +1 more source

Sex differences in global mRNA content of human skeletal muscle. [PDF]

PLoS ONE, 2009
Women oxidize more fat as compared to men during endurance exercise and several groups have shown that the mRNA content of selected genes related to fat oxidation are higher in women (e.g.
Amy C Maher, Minghua H Fu, Robert J Isfort, Alex R Varbanov, Xiaoyan A Qu, Mark A Tarnopolsky   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Synthetic dosage lethal (SDL) interaction data of Hmt1 arginine methyltransferase

Data in Brief, 2020
The introduction of methyl groups on arginine residues is catalysed by Protein Arginine Methyltransferases (PRMTs). However, the regulatory mechanisms that dictate the levels of protein arginine methylation within cells are still not completely ...
Dimitris Kyriakou, Mamantia Constantinou, Antonis Kirmizis   +2 more
doaj   +1 more source