Results 21 to 30 of about 807,043 (313)
Protein GB1 folding and assembly from structural elements. [PDF]
, 2009 Folding of the Protein G B1 domain (PGB1) shifts with increasing salt concentration from a cooperative assembly of inherently unstructured subdomains to an assembly of partly pre-folded structures.
Xue, Wei-Feng +6 more
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Quantitative Proteomics and Differential Protein Abundance Analysis after the Depletion of PEX3 from Human Cells Identifies Additional Aspects of Protein Targeting to the ER [PDF]
, 2021 Protein import into the endoplasmic reticulum (ER) is the first step in the biogenesis of around 10,000 different soluble and membrane proteins in humans. It involves the co- or post translational targeting of precursor polypeptides to the ER, and their
Schrul, Bianca +15 more
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Improved protein structure refinement guided by deep learning based accuracy estimation
Nature Communications, 2021 Here the authors present DeepAccNet, a deep learning framework that estimates per-residue accuracy and residue-residue distance signed error in protein models, which are used to guide Rosetta protein structure refinement.
Naozumi Hiranuma +5 more
doaj +1 more source
, 2012 Over the recent years, biochemistry has become responsible for explaining living processes such that many scientists in the life sciences from agronomy to medicine are engaged in biochemical research.
core +1 more source
Common transthyretin-derived amyloid fibril structures in patients with hereditary ATTR amyloidosis
Nature Communications, 2023 Systemic ATTR amyloidosis is an increasingly important protein misfolding disease that is provoked by the formation of amyloid fibrils from transthyretin protein.
Maximilian Steinebrei +8 more
doaj +1 more source
Comparative biochemistry of antarctic proteins
Comparative Biochemistry and Physiology Part A: Physiology, 1976 The UCD team of agricultural scientists has been studying the proteins of Antarctic species for 11 years, starting in 1964. During the first seven years, trips were made each year to Antarctica to study and obtain specimens from penguins and cold-adapted fishes.
R Feeney, D Osuga
openaire +3 more sources
Exploring Protein Sequence Space Using Computationally Directed Recombination [PDF]
, 2006 Evolution has provided us with many protein sequences. However, these sequences represent a very small fraction of the possible sequences. In the laboratory, scientists have explored areas of sequence space not represented by natural proteins both to ...
Meyer, Michelle Margaret
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Preparation of Golgi Membranes from Rat Liver
Bio-Protocol, 2014 This protocol details the isolation of enriched Golgi membranes from rat liver, using discontinuous density gradient centrifugation. This high-yield extraction method is useful for several applications, including immunoprecipitation of solubilised Golgi ...
Carmen Valente +4 more
doaj +1 more source
EFSA Journal, 2018 The goal of this research is to better address the problems related to the widespread presence of pesticides in the environment. Despite the unquestionable utility of the pesticides against various pests in the agricultural field, most pesticides and the
Institute of Protein Biochemistry – National Research Council, Naples, Italy +2 more
doaj +1 more source
Development and Validation of Optimization Methods for the Design of Protein Sequences and Combinatorial Libraries [PDF]
, 2009 To facilitate the design of protein sequences with desired properties, simulation techniques have been developed to allow large portions of amino acid sequence space to be evaluated by computer.
Allen, Benjamin Daniel
core +1 more source