Results 61 to 70 of about 7,288,800 (308)
Domain discovery method for topological profile searches in protein structures [PDF]
, 2004 We describe a method for automated domain discovery for topological profile searches in protein structures. The method is used in a system TOPStructure for fast prediction of CATH classification for protein structures (given as PDB files).
Gilbert, D, Torrance, G, Viksna, J
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Evaluation of a two-phase extraction system of carbohydrates and proteins from chlorella vulgaris utex 1803 [PDF]
, 2016 Microalgae are a valuable source of high-value products and biofuels, however the high-energy cost required for the extraction of their metabolites has kept questioning on possible industrial upgrading. The aim of this study was to evaluate the effect of
Andrés, F. +7 more
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Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
International Journal of General Medicine, 2023 Kateryna Strubchevska,1 Antonina Rachkovska,2 Daryna Krenytska,2 Vitalii Karbovskyy,3 Marko Kozyk,1 Benjamin Secor,4 Nataliia Raksha,2 Tetiana Vovk,2 Olexii Savchuk,2 Tetyana Falalyeyeva,2 Rostyslav Kaminsky,5 Liudmyla Ostapchenko2 1Department of ...
Strubchevska K +11 more
doaj
Altered Function of the DnaJ Family Cochaperone DNJ-17 Modulates Locomotor Circuit Activity in a Caenorhabditis elegans Seizure Model. [PDF]
, 2016 The highly conserved cochaperone DnaJ/Hsp40 family proteins are known to interact with molecular chaperone Hsp70, and can regulate many cellular processes including protein folding, translocation, and degradation.
Jin, Yishi, Takayanagi-Kiya, Seika
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Modeling Zymogen Protein C [PDF]
Biophysical Journal, 2000 A solution structure for the complete zymogen form of human coagulation protein C is modeled. The initial core structure is based on the x-ray crystallographic structure of the gamma-carboxyglutamic acid (Gla)-domainless activated form. The Gla domain (residues 1-48) is modeled from the x-ray crystal coordinates of the factor VII(a)/tissue factor ...
Perera, Lalith +6 more
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Thorax, 2005 Pneumonia is characterised by a disturbed alveolar fibrin turnover which is the net result of activation of coagulation and attenuation of fibrinolysis.1,2 We have recently shown, in patients developing ventilator associated pneumonia (VAP), that suppression of fibrinolysis precedes the clinical diagnosis while procoagulant effects mainly occur ...
Choi, G +5 more
openaire +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Nature Communications, 2023 RNA-binding proteins (RBPs) are key players regulating RNA processing and are associated with disorders ranging from cancer to neurodegeneration. Here, we present a proteomics workflow for large-scale identification of RBPs and their RNA-binding regions ...
Meeli Mullari +8 more
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