Results 81 to 90 of about 25,791,466 (309)
, 2010 Overproduction of membrane proteins can be a cumbersome task, particularly if high yields are desirable. NADH:quinone oxidoreductase (complex I) contains several very large membrane-spanning protein subunits that hitherto have been impossible to express ...
Gorecki, Kamil +17 more
core +1 more source
Reciprocal antagonism between inflammation and the protein C system
Romanian Journal of Laboratory Medicine, 2013 Proteina C, o protează serinică dependentă de vitamina K, sintetizată in hepatocite ca zimogen inactiv, se activează sub acţiunea trombinei în complex cu trombomodulina endotelială. Un receptor endotelial al proteinei C (EPCR) intervine atât în activarea
Cucuianu Mircea +5 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Early steps in mitochondrial protein import [PDF]
, 1990 The process of insertion of precursor proteins into mitochondrial membranes was investigated using a hybrid protein (pSc1-c) that contains dual targeting information and, at the same time, membrane insertion activity.
Stuart, Rosemary A. +2 more
core +1 more source
Epidemiological Characteristics and Etiology of Budd-Chiari Syndrome in Upper Egypt
Journal of Blood Medicine, 2020 Muhamad R Abdel Hameed,1 Esam Abdel-Moneim Sadek Elbeih,1 Heba Mahmoud Abd El-Aziz,2 Ola Abdel-Haleem Afifi,3 Lamiaa Mohammed Refaat Khalaf,4 Mohammed Zakaria Ali Abu Rahma,5 Abeer Sabry6 1Department of Internal Medicine & Hematology Unit, Assiut ...
Abdel Hameed MR +6 more
doaj
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Levels of protein C and activated protein C: what do they mean?
Critical care (London, England), 2006 Acute pancreatitis is a local inflammatory process that leads to a systemic inflammatory response in the majority of cases, and sometimes leads to multiple organ failure. It is obvious that coagulation and especially the protein C system are involved in this disease.
openaire +3 more sources
Protein C preserves microcirculation in a model of neonatal septic shock [PDF]
, 2009 Objectives: Sepsis remains a disease with a high mortality in neonates. Microcirculatory impairment plays a pivotal role in the development of multiorgan failure in septic newborns.
Nold, Marcel Friedrich +4 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source