Results 21 to 30 of about 6,585,847 (336)
Nano letters (Print), 2021 For nanocarriers with low protein affinity, we show that the interaction of nanocarriers with cells is mainly affected by the density, the molecular weight, and the conformation of polyethylene glycol (PEG) chains bound to the nanocarrier surface.
Mengyi K. Li +8 more
semanticscholar +1 more source
Structural Changes of RNA in Complex with Proteins in the SRP
Frontiers in Molecular Biosciences, 2018 The structural flexibility of RNA allows it to exist in several shapes and sizes. Thus, RNA is functionally diverse and is known to be involved in processes such as catalysis, ligand binding, and most importantly, protein recognition.
Janine K. Flores, Sandro F. Ataide
doaj +1 more source
Sequence-Dependent Correlated Segments in the Intrinsically Disordered Region of ChiZ
Biomolecules, 2020 How sequences of intrinsically disordered proteins (IDPs) code for their conformational dynamics is poorly understood. Here, we combined NMR spectroscopy, small-angle X-ray scattering (SAXS), and molecular dynamics (MD) simulations to characterize the ...
Alan Hicks +3 more
doaj +1 more source
Limited proteolysis in the investigation of beta2-microglobulin amyloidogenic and fibrillar states. [PDF]
, 2005 Amyloid fibrils of patients treated with regular haemodialysis essentially consists of β2-microglobulin (β2-m) and its truncated species ΔN6β2-m lacking six residues at the amino terminus.
AMORESANO, ANGELA +4 more
core +1 more source
Biosurface and Biotribology, 2022 Understanding material‐protein interactions is the basis for regulating material‐blood interactions, which is a common topic of interest for medical material developers.
Xiao Chen, Jiang Chen, Nan Huang
doaj +1 more source
Filter Retardation Assay for Detecting and Quantifying Polyglutamine Aggregates Using Caenorhabditis elegans Lysates [PDF]
, 2018 Protein aggregation is a hallmark of several neurodegenerative diseases and is associated with impaired protein homeostasis. This imbalance is caused by the loss of the protein's native conformation, which ultimately results in its aggregation or ...
Mata Cabana, Alejandro +3 more
core +2 more sources
Identifying the protein folding nucleus using molecular dynamics [PDF]
, 2000 Molecular dynamics simulations of folding in an off-lattice protein model reveal a nucleation scenario, in which a few well-defined contacts are formed with high probability in the transition state ensemble of conformations.
Buldyrev, Sergey V. +3 more
core +1 more source
Exploring the Levinthal limit in protein folding [PDF]
, 2017 According to the thermodynamic hypothesis, the native state of proteins is uniquely defined by their amino acid sequence. On the other hand, according to Levinthal, the native state is just a local minimum of the free energy and a given amino acid ...
B Fazi +23 more
core +1 more source
Frontiers in Molecular Biosciences, 2018 The stereoselective flavoenzyme D-amino acid oxidase (DAAO) catalyzes the oxidative deamination of neutral and polar D-amino acids producing the corresponding α-keto acids, ammonia, and hydrogen peroxide.
Silvia Sacchi +4 more
doaj +1 more source
Effect of Extrusion Parameters on Soybean Protein Conformation [PDF]
Shipin Kexue, 2023 The study investigated the effect of different extrusion parameters: temperature, material moisture of raw material, and screw speed on the conformation of soybean protein.
ZHANG Haojia, ZHU Xiuqing, SUN Ying
doaj +1 more source