Results 1 to 10 of about 542,906 (295)

SARST2 high-throughput and resource-efficient protein structure alignment against massive databases

Nature Communications
The flood of protein structural Big Data is coming. With the belief that biotech researchers deserve powerful analysis engines to overcome the challenge of rapidly increasing computational demands, we are devoted to developing efficient protein ...
Wei-Cheng Lo, Arieh Warshel, Chia-Hua Lo, Chia Yee Choke, Yan-Jie Li, Shih-Chung Yen, Jyun-Yi Yang, Shih-Wen Weng   +7 more
doaj   +1 more source

Using random forests for assistance in the curation of G-protein coupled receptor databases

BioMedical Engineering OnLine, 2017
Background Biology is experiencing a gradual but fast transformation from a laboratory-centred science towards a data-centred one. As such, it requires robust data engineering and the use of quantitative data analysis methods as part of database curation.
Aleksei Shkurin, Alfredo Vellido
doaj   +1 more source

OpenCustomDB: Integration of Unannotated Open Reading Frames and Genetic Variants to Generate More Comprehensive Customized Protein Databases. [PDF]

J Proteome Res, 2023
Guilloy N, Brunet MA, Leblanc S, Jacques JF, Hardy MP, Ehx G, Lanoix J, Thibault P, Perreault C, Roucou X.   +9 more
europepmc   +1 more source

dbMPIKT: a database of kinetic and thermodynamic mutant protein interactions

BMC Bioinformatics, 2018
Background Protein-protein interactions (PPIs) play important roles in biological functions. Studies of the effects of mutants on protein interactions can provide further understanding of PPIs.
Quanya Liu, Peng Chen, Bing Wang, Jun Zhang, Jinyan Li   +4 more
doaj   +1 more source

Structure-Activity Predictions From Computational Mining of Protein Databases to Assist Modular Design of Antimicrobial Peptides. [PDF]

Front Microbiol, 2022
Feurstein C, Meyer V, Jung S.
europepmc   +1 more source

ProteoDisco: a flexible R approach to generate customized protein databases for extended search space of novel and variant proteins in proteogenomic studies. [PDF]

Bioinformatics, 2022
van de Geer WS, van Riet J, van de Werken HJG.   +2 more
europepmc   +1 more source

InSilico Proteomics System: Integration and Application of Protein and Protein-Protein Interaction Data using Microsoft .NET

Journal of Integrative Bioinformatics, 2006
In the last decades, biological databases became the major knowledge resource for researchers in the field of molecular biology. The distribution of information among these databases is one of the major problems.
Straßer Wolfgang, Siegl Doris, Önder Kamil, Bauer Johann   +3 more
doaj   +1 more source

Structural Bioinformatics: Computational Software and Databases for the Evaluation of Protein Structure

RADS Journal of Biological Research & Applied Science, 2018
Databases are the computerized platform where information is stored and can be retrieved easily by public users. Biological databases are the repositories of biological data.
Ayisha Amanullah, Suad Naheed
doaj  

De novo peptide databases enable protein-based stable isotope probing of microbial communities with up to species-level resolution

Environmental Microbiome
Background Protein-based stable isotope probing (Protein-SIP) is a powerful approach that can directly link individual taxa to activity and substrate assimilation, elucidating metabolic pathways and trophic relationships within microbial communities.
Simon Klaes, Christian White, Lisa Alvarez-Cohen, Lorenz Adrian, Chang Ding   +4 more
doaj   +1 more source

Post translational Modifications and Protein-Protein Interactome of Endemic Pemphigus in El Bagre, Colombia: A New Variant Analysis

Dermatology Practical & Conceptual
Background: A new variant of endemic pemphigus foliaceus, El Bagre-EPF, is an orphan autoimmune disease occurring in El Bagre and neighboring municipalities in Colombia, South America.
Ana Maria Abreu Velez, Mariana Ramirez-Posada, Michael S Howard   +2 more
doaj   +1 more source