Results 211 to 220 of about 1,734,521 (378)

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

POT, an optogenetics-based endogenous protein degradation system. [PDF]

Commun Biol
Chen Y, Wang S, Zhang L, Peng D, Huang K, Ji B, Fu J, Xu Y.   +7 more
europepmc   +1 more source

Protein Degradation in Cultured Cells

, 1973
Brian D. Poole, Maurice Wibo
openalex   +1 more source

A method for the analysis of protein turnover characteristics. Indirect estimation of rates of protein degradation [PDF]

, 1978
Norman Paskin, R. John Mayer
openalex   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

A TRIM21-based method for targeted protein degradation. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Hu W, Qiu X, Yang Y, Wu Y, Wang C, Hu R, Li C.   +6 more
europepmc   +1 more source

Studies on the Correlation between Size and Relative Degradation Rate of Soluble Proteins

, 1973
J. Fred Dice, Peter J. Dehlinger, Robert Schimke   +2 more
openalex   +1 more source

Bacteriophage T4 Inhibits Colicin E2-Induced Degradation of Escherichia coli Deoxyribonucleic Acid I. Protein Synthesis-Dependent Inhibition [PDF]

, 1971
Robert Swift, John S. Wiberg
openalex   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Rapid protein degradation systems to determine gene function in vivo. [PDF]

Lab Anim (NY)
Scott TG, Guertin MJ.
europepmc   +1 more source