Results 281 to 290 of about 5,941,139 (381)

Phenylalanine‐Based DNA‐Encoded Chemical Libraries for the Discovery of Potent and Selective Small Organic Ligands Against Markers of Cancer and Immune Cells

Advanced Science, EarlyView.
FM‐DEL1 and FM‐DEL2 are constructed by installing one or two sets of building blocks on a phenylalanine central scaffold. FM‐DELs are screened against markers of prostate, and renal cell carcinoma, and against an immunological target expressed on the surface of natural killer cells.
Francesca Migliorini, Andrea Ciamarone, Sheila Dakhel Plaza, Tony Georgiev, Marta Mascellani, Emanuela Sabato, Giulio Vistoli, Ilaria Biancofiore, Nicholas Favalli, Emanuele Puca, Sebastian Oehler, Dario Neri, Samuele Cazzamalli   +12 more
wiley   +1 more source

Single‐Droplet Dual‐Target Quantification of circRNA Biomarkers for Colorectal Cancer Screening

Advanced Science, EarlyView.
Circular RNAs are crucial in tumorigenesis. This study identifies circCK1γ3 and circWDR37 as dual plasma biomarkers for colorectal cancer (CRC) screening. It is developed Casµchip, a droplet microfluidic chip using Cas13a/b technology to quantify these biomarkers.
Jingsong Xu, Yu Liu, Junheng Zhang, Shuang Yang, Tianming Li, Haiqian Huang, Qian Liu, Hengliang Wang, Li Cao, Zhenghua An, Min Li, Hua Wang   +11 more
wiley   +1 more source

Effect of Protein Hydrolysate of Pearl Oyster Meat on the State of Water and Denaturation of Fish Myofibrils during Dehydration.

, 1997
Darmanto Darmanto, Hisashi Ichikawa, Mitsunori Iwamoto, Naoyuki Abe, Shingo Nishimura, Shinji Goto, Yukinori Nozaki   +6 more
openalex   +2 more sources

Engineering Decavalent, Sperm‐Binding Laminin‐IgG Hybrid Antibodies for Potent Non‐Hormonal Contraception

Advanced Science, EarlyView.
This study investigates a highly multivalent mAb platform fusing Laminin‐511 heterotrimerization domains with Fabs and IgG1‐Fc as a non‐hormonal contraceptive. The most potent molecule ‘LamH10’, possessing 10 Fabs, rapidly achieved >99% reduction in progressively motile sperm at just 33µg per dose in sheep, making the laminin‐IgG hybrid platform the ...
Alison Schaefer, Keiichiro Kushiro, Bhawana Shrestha, Yong Zhu, Alysha Panjwani, Lauren Dawson, Haley Flowers, Kathleen L. Vincent, Samuel K. Lai   +8 more
wiley   +1 more source

Thermodynamics of Protein Denaturation.

Seibutsu Butsuri, 1995
openaire   +3 more sources

A Needle‐Like H2S‐Releasing and H2O2 Self‐Replenishing Nanoplatform for Enhanced Chemodynamic Tumor Immunotherapy

Advanced Science, EarlyView.
The PTA‐SnS2@GOx cascade nanosystem presents a smart paradigm for cancer theranostics, integrating self‐supplied H2S/H2O2‐augmented chemodynamic therapy (CDT) with sensitized immunotherapy. Its needle‐like SnS2 shell enhances tumor‐specific uptake, ensuring biosafety.
Xiaoxiao Sun, Xia Zhang, Haiyan Qin, Lingling Li   +3 more
wiley   +1 more source

Denaturation of Myofibrillar Protein in Myctophid Fish During Refrigeration and Freezing Storage

, 1997
Hwan‐Sook Seo, Yasushi Endo, Kenshiro Fujimoto, Masatoshi Moku, Kouichi Kawaguchi   +4 more
openalex   +2 more sources

Entropy-driven denaturation enables sustainable protein regeneration through rapid gel-solid transition. [PDF]

Nat Commun
Wang Y, Liu J, Peters MM, Ishii R, Wang D, Chowdhury S, Parker KK, Shakhnovich EI.   +7 more
europepmc   +1 more source

Simple Protein Foaming‐Derived 3D Segregated MgO Networks in Epoxy Composites with Outstanding Thermal Conductivity Properties

Advanced Science, EarlyView.
MgO‐based composites with highly interconnected filler networks are fabricated using a simple, eco‐friendly protein foaming method. Liquid‐phase‐assisted sintering enhanced bonding with the matrix. The interconnected structured filler composites exhibit significantly improved thermal conductivity, exceeding that of pure epoxy, randomly dispersed ...
Su‐Jin Ha, Young Kook Moon, Jong‐Jin Choi, Byung‐Dong Hahn, Cheol‐Woo Ahn, Kyung‐Hoon Cho, Hyun‐Ae Cha   +6 more
wiley   +1 more source

Enhanced Protein Photo-Stability Analysis Using SRCD in the Presence of Phospholipid SUVs. [PDF]

Chemistry
Honisch C, Rotondo M, Monaco M, Tartaggia S, Hussain R, Siligardi G, Ruzza P.   +6 more
europepmc   +1 more source