Results 101 to 110 of about 3,285 (194)

Gaining extensive resistance against clubroot disease through the disruption of a susceptibility gene

Journal of Integrative Plant Biology, EarlyView.
This Commentary examines research by Wu et al. showing that β‐1,3‐glucan synthase‐like 5 (GSL5) functions as a key gene for susceptibility to clubroot in Brassica family members by suppressing immunity regulated by jasmonic acid. Inaction of GSL5 through genome editing provides broad‐spectrum resistance to clubroot.
Qibin Wu, Zhen Zeng, Daowen Wang, Zheng Qing Fu, Youxiong Que   +4 more
wiley   +1 more source

The Arabidopsis Protein Disulfide Isomerase Subfamily M Isoform, PDI9, Localizes to the Endoplasmic Reticulum and Influences Pollen Viability and Proper Formation of the Pollen Exine During Heat Stress

Frontiers in Plant Science, 2020
Plants adapt to heat via thermotolerance pathways in which the activation of protein folding chaperones is essential. In eukaryotes, protein disulfide isomerases (PDIs) facilitate the folding of nascent and misfolded proteins in the secretory pathway by ...
Elizabeth Feldeverd, Brad W. Porter, Christen Y. L. Yuen, Kaela Iwai, Rina Carrillo, Tyler Smith, Cheyenne Barela, Katherine Wong, Pengfei Wang, Byung-Ho Kang, Kristie Matsumoto, David A. Christopher   +11 more
doaj   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

A Fungal Cysteine‐Rich Protein SsSCP Activates Immune Responses and Confers Broad‐Spectrum Disease Resistance in Tomato

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant immune systems recognise pathogen‐derived molecular patterns to activate defence responses, yet the mechanisms underlying fungal pattern recognition in crops remain largely unclear. Here, we characterise the cysteine‐rich secretory protein SsSCP from the broad‐host‐range fungal pathogen Sclerotinia sclerotiorum as a potent elicitor of ...
Liyuan Zhang, Yuan Wang, Yuhang Liu, Jinwen Yang, Kaihao Zhang, Chengzhang Du, Jiajing Xiao, Ling Qing, Xinhua Sun   +8 more
wiley   +1 more source

Activity‐Based Protein Profiling Identifies Protein Disulfide‐Isomerases as Target Proteins of the Volatile Salinilactones

Advanced Science
The salinilactones, volatile marine natural products secreted from Salinispora arenicola, feature a unique [3.1.0]‐lactone ring system and cytotoxic activities through a hitherto unknown mechanism.
Karoline Jerye, Helko Lüken, Anika Steffen, Christian Schlawis, Lothar Jänsch, Stefan Schulz, Mark Brönstrup   +6 more
doaj   +1 more source

A Study on the Alteration of Endoplasmic Reticulum Stress-related Proteins in Cyclophosphamide-induced Damage to Urothelium [PDF]

Pharmaceutical and Biomedical Research, 2023
Background: Cyclophosphamide is widely prescribed as an anti-cancer drug and used as an immunosuppressant. Hemorrhagic cystitis is one of the common complications of cyclophosphamide intake.
Hemalatha R, Muthuraman N, Sandya Rani, Premila Abraham   +3 more
doaj  

Quiescin Sulfhydryl Oxidase‐Like 1 Positively Regulates Seed Dormancy in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Seed dormancy is an adaptive strategy that enables plants to survive adverse environmental conditions. In agricultural contexts, an optimal level of dormancy is essential: Insufficient dormancy can result in preharvest sprouting, while excessive dormancy may lead to uneven germination and poor stand establishment in subsequent crops.
Tengfei Ma, Qian Wang, Tao Wu, Qixian Hao, Yunshuai Huang, Changling Mou, Rong Miao, Jie Lan, Fulin Zhang, Ping Wang, Ziyan Zhu, Kunhao Li, Jiawei Song, Chen Hu, Yingying Chen, Boliang Lu, Yiwan Wu, Shijia Liu, Ling Jiang, Jianmin Wan   +19 more
wiley   +1 more source

Natural Products Targeting Protein Disulfide Isomerases: New Frontiers for Diabetes, Cancer, and Coagulation

Food Frontiers
The protein disulfide isomerase (PDI) family comprises 21 members that have oxidase, reductase, isomerase, and foldase activities essential for human health and disease. Protein disulfide isomerase A4 (PDIA4) is the largest member in this family.
Yi‐San Lee, Catherine Ortega, Tien‐Fen Kuo, Greta Yang, Wen‐Chin Yang   +4 more
doaj   +1 more source

Phylogenetic Relationship of Bombyx mori Protein Disulfide Isomerase

Zeitschrift für Naturforschung C, 2002
A cDNA that encodes protein disulfide isomerase was isolated from Bombyx mori (bPDI), in which an open reading frame of 494 amino acids contained two PDI-typical thioredoxin active sites of WCGHCK and an ER retention signal of the KDEL motif at its C-terminal. The bPDI protein shared less than 55% of the amino acid sequence homology with other reported
Tae Won, Goo, Eun Young, Yun, Jae-Sam, Hwang, Seok-Woo, Kang, Kwan-Hee, You, O Yu, Kwon   +5 more
openaire   +2 more sources

Improving End‐Use Quality Through Introducing Cysteines Into the Central Repeat Domain of High‐Molecular‐Weight Glutenin Subunit 1Dx2 in Bread Wheat

Plant Biotechnology Journal, EarlyView.
ABSTRACT In bread wheat (Triticum aestivum L.), cysteine (Cys) residues within the N‐ and C‐termini of high‐molecular‐weight glutenin subunits (HMW‐GSs) critically influence dough quality. However, the functional significance of Cys residue in their central repeat domain (CRD) remains unclear.
Bo Wei, Lujun Zhang, Renchun Fan, Qi Zhang, Jiazhu Sun, Changbin Yin, Dongcheng Liu, Xiukun Liu, Aifeng Liu, Yuling Jiao, Caixia Gao, Xu Jia, Xianping Wang, Aimin Zhang, Xinyou Cao, Daowen Wang, Xiangqi Zhang   +16 more
wiley   +1 more source