Results 31 to 40 of about 1,414,042 (194)
Nature Communications, 2019 The formation of cilia depends on centriole’s distal appendages. Here, the authors use correlative 3D-superresolution, electron microscopy and electron tomography to detail the architecture of distal appendages, to describe the initial stages of ...
Mathew Bowler +9 more
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Nature Communications, 2022 Iron is an essential mineral in plant physiology. YS1 transporter imports iron–phytosiderophore complex (Fe(III)–DMA) from the soil. Here, the authors describe the cryo-EM structures of barley YS1 in complex with substrate, and a synthetic substrate ...
Atsushi Yamagata +5 more
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Logarithmic decay in single-particle relaxations of hydrated lysozyme powder
, 2009 We present the self-dynamics of protein amino acids of hydrated lysozyme powder around the physiological temperature by means of molecular dynamics (MD) simulations.
Baglioni, Piero +2 more
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Microscopic mechanism of protein cryopreservation in an aqueous solution with trehalose [PDF]
, 2013 In order to investigate the cryoprotective mechanism of trehalose on proteins, we use molecular dynamics computer simulations to study the microscopic dynamics of water upon cooling in an aqueous solution of lysozyme and trehalose.
Corradini, Dario +3 more
core +1 more source
Functional Dynamics of Proteins [PDF]
Computational and Mathematical Methods in Medicine, 2012 X-ray crystallography captures protein conformational states that are stable enough to be captured. These observable states are simply part of the functional event in the context of protein dynamics. Life at the molecular level has a vibrant nature at physiological temperature, governed by physics laws. Molecular dynamics (MDs) simulations have been
Yang, Lee-Wei +4 more
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Characterization of the Transition State of Functional Enzyme Dynamics [PDF]
, 2006 Through characterization of the solvent isotope effect on protein dynamics, we have examined determinants of the rate limitation to enzyme catalysis. A global conformational change in Ribonuclease A limits the overall rate of catalytic turnover.
Kovriguine, Evgueni, Loria, J. Patrick
core +2 more sources
Nature CommunicationsWe describe a modified version of AlphaFold2 that incorporates experimental distance distributions into the network architecture for protein structure prediction.
Tianqi Wu +4 more
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Sustained enzymatic activity and flow in crowded protein droplets
Nature Communications, 2021 Living cells can harvest environmental energy to drive chemical processes. Here the authors design a minimal artificial system that achieves steady states at similar metabolic densities to microorganisms.
Andrea Testa +7 more
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Detection of Side Chain Rearrangements Mediating the Motions of Transmembrane Helices in Molecular Dynamics Simulations of G Protein-Coupled Receptors. [PDF]
, 2017 Structure and dynamics are essential elements of protein function. Protein structure is constantly fluctuating and undergoing conformational changes, which are captured by molecular dynamics (MD) simulations.
Gaieb, Zied, Morikis, Dimitrios
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Dynamically driven protein allostery [PDF]
Nature Structural & Molecular Biology, 2006 Allosteric interactions are typically considered to proceed through a series of discrete changes in bonding interactions that alter the protein conformation. Here we show that allostery can be mediated exclusively by transmitted changes in protein motions.
Nataliya, Popovych +3 more
openaire +2 more sources