Results 211 to 220 of about 8,703,040 (401)

Protein Engineering Technologies for Development of Next-Generation Genome Editors. [PDF]

Curr Opin Biomed Eng, 2023
Winter J, Shirguppe S, Perez-Pinera P.
europepmc   +1 more source

Introduction to the Experiment of Genetic Engineering. X. protein engineering

, 1988
Hiroyuki Adachi, Hiroshi Matsuzawa
openalex   +2 more sources

Clinical significance of stratifying prostate cancer patients through specific circulating genes

Molecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian, Edouard Jarry, Arynne Santos, Quentin Vesval, Lucie Hamel, Rafael Sanchez‐Salas, Alexis Rompré‐Brodeur, Wassim Kassouf, Raghu Rajan, Fadi Brimo, Marie Duclos, Armen Aprikian, Simone Chevalier   +12 more
wiley   +1 more source

Effective Protein-Protein Interaction Exploration with PPIretrieval [PDF]

arXiv
Protein-protein interactions (PPIs) are crucial in regulating numerous cellular functions, including signal transduction, transportation, and immune defense. As the accuracy of multi-chain protein complex structure prediction improves, the challenge has shifted towards effectively navigating the vast complex universe to identify potential PPIs. Herein,
arxiv  

Protein engineering via sequence-performance mapping. [PDF]

Cell Syst, 2023
McConnell A, Hackel BJ.
europepmc   +1 more source

Protein Engineering paper cited onto Red Hot Research list [PDF]

, 1999

openalex   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Inteins-mechanism of protein splicing, emerging regulatory roles, and applications in protein engineering. [PDF]

Front Microbiol, 2023
Wood DW, Belfort M, Lennon CW.
europepmc   +1 more source

Protein engineering

Current Opinion in Biotechnology, 1991
openaire   +2 more sources

The second cycle of a protein engineering project: the replacement of a loop in monomeric triosephosphate isomerase (monotim) [PDF]

, 1996
R.K. Wierenga, Narmada Thanki, Wolfgang Schliebs, Johan Zeelen, Ruben Abagyan, Rainer Jaenicke   +5 more
openalex   +1 more source