Results 11 to 20 of about 3,575,397 (313)

Structural and Functional Studies of H. seropedicae RecA Protein - Insights into the Polymerization of RecA Protein as Nucleoprotein Filament. [PDF]

open access: yesPLoS ONE, 2016
The bacterial RecA protein plays a role in the complex system of DNA damage repair. Here, we report the functional and structural characterization of the Herbaspirillum seropedicae RecA protein (HsRecA). HsRecA protein is more efficient at displacing SSB
Wellington C Leite   +9 more
doaj   +1 more source

Quantifying Protein Diffusion and Capture on Filaments [PDF]

open access: yesBiophysical Journal, 2015
13 pages, 7 ...
Reithmann, Emanuel   +2 more
openaire   +3 more sources

Distribution of glial fibrillary acidic protein in different parts of the rat brain under cadmium exposure [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2015
The chronic effects of low doses of cadmium on the distribution of soluble and filament forms of glial fibrillary acidic protein (GFAP) and their polypeptide fragments in different parts of the rat brain were investigated.
Yu. P. Kovalchuk   +6 more
doaj   +1 more source

Sarcomere lattice geometry influences cooperative myosin binding in muscle. [PDF]

open access: yesPLoS Computational Biology, 2007
In muscle, force emerges from myosin binding with actin (forming a cross-bridge). This actomyosin binding depends upon myofilament geometry, kinetics of thin-filament Ca(2+) activation, and kinetics of cross-bridge cycling.
Bertrand C W Tanner   +2 more
doaj   +1 more source

Structure of the hDmc1-ssDNA filament reveals the principles of its architecture [PDF]

open access: yes, 2010
In eukaryotes, meiotic recombination is a major source of genetic diversity, but its defects in humans lead to abnormalities such as Down's, Klinefelter's and other syndromes.
Dmitry V Bugreev   +23 more
core   +2 more sources

The Biological Role of Nestin(+)-Cells in Physiological and Pathological Cardiovascular Remodeling

open access: yesFrontiers in Cell and Developmental Biology, 2018
The intermediate filament protein nestin was identified in diverse populations of cells implicated in cardiovascular remodeling. Cardiac resident neural progenitor/stem cells constitutively express nestin and following an ischemic insult migrate to the ...
Angelino Calderone, Angelino Calderone
doaj   +1 more source

Collaborative protein filaments

open access: yesThe EMBO Journal, 2015
Abstract It is now well established that prokaryotic cells assemble diverse proteins into dynamic cytoskeletal filaments that perform essential cellular functions. Although most of the filaments assemble on their own to form higher order structures, growing evidence suggests that there are a number of prokaryotic proteins that ...
Ghosal, D, Loewe, J
openaire   +3 more sources

Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis [PDF]

open access: yes, 2005
Several kinases phosphorylate vimentin, the most common intermediate filament protein, in mitosis. Aurora-B and Rho-kinase regulate vimentin filament separation through the cleavage furrow-specific vimentin phosphorylation.
Erich A. Nigg   +19 more
core   +1 more source

A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks

open access: yesNature Communications, 2021
The assembly of branched actin networks depends on the heterodimeric capping protein CP/CapZ. Combining cryoEM, in vitro reconstitution and cell biological assays, the authors show that CP not only prevents actin filament elongation but also selectively ...
Johanna Funk   +5 more
doaj   +1 more source

The N-Terminal Part of the 1A Domain of Desmin Is a Hot Spot Region for Putative Pathogenic DES Mutations Affecting Filament Assembly

open access: yesCells, 2022
Desmin is the major intermediate filament protein of all three muscle cell types, and connects different cell organelles and multi-protein complexes such as the cardiac desmosomes. Several pathogenic mutations in the DES gene cause different skeletal and
Andreas Brodehl   +3 more
doaj   +1 more source

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