Results 241 to 250 of about 250,840 (309)

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

open access: yesAdvanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck   +8 more
wiley   +1 more source

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

open access: yesAdvanced Science, EarlyView.
Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera   +10 more
wiley   +1 more source

ACTA1-Related Adult-Onset Scapuloperoneal Myopathy With Cores and Rods. [PDF]

open access: yesNeuropathol Appl Neurobiol
Caramizaru A   +10 more
europepmc   +1 more source

Filament formation and NAD processing by noncanonical human FAM118 sirtuins. [PDF]

open access: yesNat Struct Mol Biol
Baretić D   +23 more
europepmc   +1 more source

The Role of Actin-Binding Proteins in Breast Cancer Progression. [PDF]

open access: yesBreast Cancer (Dove Med Press)
Alfarafisa NM   +4 more
europepmc   +1 more source

Molecular characterisation of the Bacillus subtilis SpbK antiphage defence system. [PDF]

open access: yesNat Commun
Mishra BP   +15 more
europepmc   +1 more source

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