Results 21 to 30 of about 257,652 (357)

Bre1/RNF20 promotes Rad51-mediated strand exchange and antagonizes the Srs2/FBH1 helicases

open access: yesNature Communications, 2023
Central to homologous recombination (HR) is the assembly of Rad51 recombinase on single-strand DNA (ssDNA), forming the Rad51-ssDNA filament. How the Rad51 filament is efficiently established and sustained remains partially understood. Here, we find that
Guangxue Liu   +14 more
doaj   +1 more source

The DinI Protein Stabilizes RecA Protein Filaments [PDF]

open access: yesJournal of Biological Chemistry, 2004
When DinI is present at concentrations that are stoichiometric with those of RecA or somewhat greater, DinI has a substantial stabilizing effect on RecA filaments bound to DNA. Exchange of RecA between free and bound forms was almost entirely suppressed, and highly stable filaments were documented with several different experimental methods.
Shelley L, Lusetti   +4 more
openaire   +2 more sources

Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination [PDF]

open access: yes, 2015
In meiotic DNA recombination, the Hop2-Mnd1 complex promotes Dmc1-mediated single-stranded DNA (ssDNA) invasion into homologous chromosomes to form a synaptic complex by a yet-unclear mechanism.
Alexandra-Styliani Kalantzi   +66 more
core   +3 more sources

Histidine-Dependent Protein Methylation Is Required for Compartmentalization of CTP Synthase

open access: yesCell Reports, 2018
Summary: CTP synthase (CTPS) forms compartmentalized filaments in response to substrate availability and environmental nutrient status. However, the physiological role of filaments and mechanisms for filament assembly are not well understood.
Wei-Cheng Lin   +22 more
doaj   +1 more source

Actin Cytoskeleton and Golgi Involvement in Barley stripe mosaic virus Movement and Cell Wall Localization of Triple Gene Block Proteins. [PDF]

open access: yes, 2013
Barley stripe mosaic virus (BSMV) induces massive actin filament thickening at the infection front of infected Nicotiana benthamiana leaves. To determine the mechanisms leading to actin remodeling, fluorescent protein fusions of the BSMV triple gene ...
Bae, Hanhong   +10 more
core   +2 more sources

Construction and Loss of Bacterial Flagellar Filaments

open access: yesBiomolecules, 2020
The bacterial flagellar filament is an extracellular tubular protein structure that acts as a propeller for bacterial swimming motility. It is connected to the membrane-anchored rotary bacterial flagellar motor through a short hook.
Xiang-Yu Zhuang, Chien-Jung Lo
doaj   +1 more source

The F-actin filament capping protein CapG is a bona fide nucleolar protein [PDF]

open access: yes, 2008
Actin works in concert with myosin I to regulate the transcription of ribosomal genes in the nucleolus. Recently, nucleolar actin has been shown to be active in its polymeric form raising the question how actin dynamics is regulated in the nucleolus ...
Gettemans, Jan   +3 more
core   +2 more sources

A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion.

open access: yesPLoS Biology, 2019
Type III protein-secretion machines are essential for the interactions of many pathogenic or symbiotic bacterial species with their respective eukaryotic hosts. The core component of these machines is the injectisome, a multiprotein complex that mediates
Emily Z Guo   +8 more
doaj   +1 more source

Effects of truncations in the N‐ and C‐terminal domains of filensin on filament formation with phakinin in cell‐free conditions and cultured cells

open access: yesFEBS Open Bio, 2023
Filensin and phakinin are lens fiber cell‐specific proteins that constitute the beaded filaments (BFs) that are critical for maintaining lens transparency. In the Shumiya cataract rat, filensin 94 kDa undergoes N‐ and C‐terminal proteolytic processing to
Moe Tashiro   +6 more
doaj   +1 more source

Activation of ADF/cofilin by phosphorylation-regulated Slingshot phosphatase is required for the meiotic spindle assembly in Xenopus laevis oocytes [PDF]

open access: yes, 2013
We identify Xenopus ADF/cofilin (XAC) and its activator, Slingshot phosphatase (XSSH), as key regulators of actin dynamics essential for spindle microtubule assembly during Xenopus oocyte maturation.
Abe, Hiroshi   +9 more
core   +1 more source

Home - About - Disclaimer - Privacy