Results 71 to 80 of about 257,652 (357)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Genetic dissection of novel myopathy models reveals a role of CapZα and Leiomodin 3 during myofibril elongation.

PLoS Genetics, 2022
Myofibrils within skeletal muscle are composed of sarcomeres that generate force by contraction when their myosin-rich thick filaments slide past actin-based thin filaments.
Joachim Berger, Silke Berger, Yu Shan G Mok, Mei Li, Hakan Tarakci, Peter D Currie   +5 more
doaj   +1 more source

3D hybrid wound devices for spatiotemporally controlled release kinetics [PDF]

, 2012
This paper presents localized and temporal control of releasekinetics over 3-dimensional (3D) hybridwounddevices to improve wound-healing process. Imaging study is performed to extract wound bed geometry in 3D.
Koc, Bahattin, Koç, Bahattin, Ozbolat, Ibrahim T., Özbolat, İbrahim T.   +3 more
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Cryo-EM structure of AAA + ATPase thorase reveals novel helical filament formation

Computational and Structural Biotechnology Journal
The AAA+ (ATPases associated with a variety of cellular activities) ATPase, Thorase, also known as ATAD1, plays multiple roles in synaptic plasticity, mitochondrial quality control and mTOR signaling through disassembling protein complexes like AMPAR and
Mohamad Aasif Dar, Robert Louder, Marisol Cortes, Rong Chen, Qianqian Ma, Mayukh Chakrabarti, George K.E. Umanah, Ted M. Dawson, Valina L. Dawson   +8 more
doaj   +1 more source

Cysteine-rich protein 1 (CRP1) regulates actin filament bundling

BMC Cell Biology, 2005
Background Cysteine-rich protein 1 (CRP1) is a LIM domain containing protein localized to the nucleus and the actin cytoskeleton. CRP1 has been demonstrated to bind the actin-bundling protein α-actinin and proposed to modulate the actin cytoskeleton ...
Fraley Tamara S, Singleton CoreyAyne, Tran Thuan C, Greenwood Jeffrey A   +3 more
doaj   +1 more source

The glycolytic enzyme phosphofructokinase-1 assembles into filaments. [PDF]

, 2017
Despite abundant knowledge of the regulation and biochemistry of glycolytic enzymes, we have limited understanding on how they are spatially organized in the cell.
Albe, Anne M. Dosey, Attanasio, Barry, Beaty, Beckner, Bradley A. Webb, Brüser, Clarke, Cohen, De Bock, Diane L. Barber, Egelman, Egelman, Eisenberg, Foe, Frey, Gunning, Habrian, Ingerson-Mahar, Jang, Jia, Justin M. Kollman, Kemp, Kim, Lander, Li, Liu, Mahboubi, Meredith, Noree, Olsen, O’Connell, Ranjit, Reinhart, Rohou, Scheres, Scheres, Schindelin, Segall, Shaikh, Shen, Sievers, Stehbens, Stehbens, Suloway, Torsten Wittmann, Trujillo, Wang, Webb   +49 more
core   +1 more source

Myosin II filament dynamics in actin networks revealed with interferometric scattering microscopy [PDF]

, 2020
The plasma membrane and the underlying cytoskeletal cortex constitute active platforms for a variety of cellular processes. Recent work has shown that the remodeling acto-myosin network modifies local membrane organization, but the molecular details are ...
Fineberg, A., Hundt, N., Kukura, Philipp, Köster, Darius, Mayor, S., Mosby, Lewis S., Polin, Marco, Young, G.   +7 more
core   +1 more source

Intermediate filament linker proteins.

Society of General Physiologists series, 1997
Soc Gen Physiol ...
Fuchs, E., Yang, Y., Dowling, J., Kouklis, P., Smith, E., Guo, L., Yu, Q. C.   +6 more
openaire   +2 more sources

Protein glycosylation pathways in filamentous fungi [PDF]

Glycobiology, 2008
Glycosylation of proteins is important for protein stability, secretion, and localization. In this study, we have investigated the glycan synthesis pathways of 12 filamentous fungi including those of medical/agricultural/industrial importance for which genomes have been recently sequenced.
Nandan, Deshpande, Marc R, Wilkins, Nicolle, Packer, Helena, Nevalainen   +3 more
openaire   +2 more sources