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2017
Protein function is a concept that can have different interpretations in different biological contexts, and the number and diversity of novel proteins identified by large-scale "omics" technologies poses increasingly new challenges. In this review we explore current strategies used to predict protein function focused on high-throughput sequence ...
Leonardo Magalhães, Cruz +3 more
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Protein function is a concept that can have different interpretations in different biological contexts, and the number and diversity of novel proteins identified by large-scale "omics" technologies poses increasingly new challenges. In this review we explore current strategies used to predict protein function focused on high-throughput sequence ...
Leonardo Magalhães, Cruz +3 more
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Response functions of proteins
Biophysical Chemistry, 2000The thermodynamics of protein folding can be studied by a variety of different techniques such as differential scanning calorimetry, differential scanning densimetry and sound velocity measurements. These three methods monitor the different response functions heat capacity, expansion coefficient and compressibility that characterise various aspects of ...
J, Rösgen, H J, Hinz
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2021
This chapter evaluates the wide variety of ways that proteins support the structures and life processes of viruses, cells, and organisms. It begins by looking at structural proteins, enzymes and enzyme kinetics, and antibodies. The chapter then considers transmembrane transport proteins—including channels, gates, and pumps—and receptors, all embedded ...
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This chapter evaluates the wide variety of ways that proteins support the structures and life processes of viruses, cells, and organisms. It begins by looking at structural proteins, enzymes and enzyme kinetics, and antibodies. The chapter then considers transmembrane transport proteins—including channels, gates, and pumps—and receptors, all embedded ...
openaire +1 more source
Protein-Functionalized Polymer Brushes
Biomacromolecules, 2005A new strategy for the preparation of protein-functionalized polymer brushes is reported, which is based on a combination of surface-initiated atom transfer radical polymerization (ATRP), p-nitrophenyl chloroformate activation of the surface hydroxyl groups, and subsequent O(6)-benzylguanine (BG) functionalization.
Stefano, Tugulu +4 more
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Protein Hydration and Function
1991Publisher Summary Hydration can be considered a process of adding water incrementally to dry protein, until a level of hydration is reached beyond which further addition of water produces no change and only dilutes the protein. The hydration process has several stages and an end point, reflected similarly in different types of measurements.
J A, Rupley, G, Careri
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Protein surface functional description
2010 Annual International Conference of the IEEE Engineering in Medicine and Biology, 2010The paper presents an image-oriented description of artificial and biological nanostructured surfaces, with applicability to the functional characterization of atom neighborhoods at the surface of proteins. The property which is considered is the hydrophobicity around each surface atom.
P D, Cristea, R, Tuduce, O, Arsene
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S100A6 protein: functional roles
Cellular and Molecular Life Sciences, 2017S100A6 protein belongs to the A group of the S100 protein family of Ca2+-binding proteins. It is expressed in a limited number of cell types in adult normal tissues and in several tumor cell types. As an intracellular protein, S100A6 has been implicated in the regulation of several cellular functions, such as proliferation, apoptosis, the cytoskeleton ...
Rosario, Donato +2 more
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1997
Abstract The companion to this book, Protein Structure: A Practical Approach, gives methods of determining the structure of a newly discovered protein, but that is only part of the story. Protein Function: A Practical Approach completes the picture by providing the techniques for elucidating the functional properties of proteins, which ...
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Abstract The companion to this book, Protein Structure: A Practical Approach, gives methods of determining the structure of a newly discovered protein, but that is only part of the story. Protein Function: A Practical Approach completes the picture by providing the techniques for elucidating the functional properties of proteins, which ...
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Prediction of protein functions based on function–function correlation relations
Computers in Biology and Medicine, 2010A protein function pair approach, based on protein-protein interaction (PPI) data, is proposed to predict protein functions. Randomization tests are performed on the PPI dataset, which resulted in a protein function correlation scoring value which is used to rank the relative importance of a function pair.
Ka-Lok, Ng +2 more
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Protein Ubiquitylation and Synaptic Function
Annals of the New York Academy of Sciences, 2003Abstract: Conjugation of ubiquitin to proteins is a well‐established signal to regulate an ever expanding range of cellular processes. Here, we discuss recent findings that deeply link ubiquitin signaling to synaptic activity.
O. Cremona, COLLESI, CHIARA, E. Raiteri
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