Results 51 to 60 of about 5,231,311 (300)

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

Empirical Potential Function for Simplified Protein Models: Combining Contact and Local Sequence-Structure Descriptors

, 2006
An effective potential function is critical for protein structure prediction and folding simulation. Simplified protein models such as those requiring only $C_\alpha$ or backbone atoms are attractive because they enable efficient search of the ...
Adamian, Anfinsen, Avbelj, Bahar, Bastolla, Betancourt, Brooks, Buchete, Cannata, Chiu, Cline, Crasto, Dill, Dill, Dima, Dobson, Fain, Fitzkee, Fletcher, Friedrichs, Gan, Goldstein, Guntert, Hao, Head-Gordon, Hou, Hu, Hunter, Joachims, Kolinski, Kolodny, Kuang, Lazaridis, Levinthal, Levitt, Lezon, Li, Li, Liang, Loose, Lu, Maiorov, McConkey, McGuffin, Mirny, Miyazawa, Murphy, Park, Park, Pearlman, Pei, Przytycka, Riddle, Sagot, Samudrala, Samudrala, Schölkopf, Shortle, Shortle, Simons, Simons, Simons, Thomas, Tobi, Tobi, Tsai, Vendruscolo, Vendruscolo, Vriend, Wang, Wang, Xia, Xia, Zhang, Zhang, Zhang, Zhou   +76 more
core   +1 more source

AnaGram: protein function assignment [PDF]

Bioinformatics, 2004
Abstract Summary: AnaGram is a web service for protein function assignment based on identity detection of small significant fragments (protomotifs) that can act as modular pieces in peptide construction. The system is able to assign function by finding correlations between protomotifs and functional annotations contained in SWISS-PROT ...
A J, Pérez, G, Thode, O, Trelles
openaire   +2 more sources

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Biological Functions of ilvC in Branched-Chain Fatty Acid Synthesis and Diffusible Signal Factor Family Production in Xanthomonas campestris

Frontiers in Microbiology, 2017
In bacteria, the metabolism of branched-chain amino acids (BCAAs) is tightly associated with branched-chain fatty acids (BCFAs) synthetic pathways. Although previous studies have reported on BCFAs biosynthesis, more detailed associations between BCAAs ...
Kai-Huai Li, Yong-Hong Yu, Hui-Juan Dong, Wen-Bin Zhang, Jin-Cheng Ma, Hai-Hong Wang   +5 more
doaj   +1 more source

Functional protein microarray technology

WIREs Systems Biology and Medicine, 2010
AbstractFunctional protein microarrays are emerging as a promising new tool for large‐scale and high‐throughput studies. In this article, we review their applications in basic proteomics research, where various types of assays have been developed to probe binding activities to other biomolecules, such as proteins, DNA, RNA, small molecules, and glycans.
Hu, Shaohui, Xie, Zhi, Qian, Jiang, Blackshaw, Seth, Zhu, Heng   +4 more
openaire   +3 more sources

Resistant Protein: Forms and Functions

Foods, 2022
Several global health risks are related to our dietary lifestyle. As a consequence of the overconsumption of ultra-processed and highly digestible protein (150–200% of the recommended value), excess dietary proteins reach the colon, are hydrolysed to peptides and amino acids by bacterial proteases and fermented to various potentially toxic end products.
Emanuele Zannini, Aylin W. Sahin, Elke K. Arendt   +2 more
openaire   +4 more sources

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Nuclear VPS35 attenuates NHEJ repair by sequestering Ku protein

Molecular Medicine
Vacuolar protein sorting-associated protein 35 (VPS35), a pivotal constituent of the retromer complex, mediates the retrograde trafficking of endosomal cargoes in the cytoplasm.
Luping Zhang, Yonghong Nie, Tuo Tang, Yanji Lu, Wenlong Li, Xian Hong, Qiang Li, Aixue Zheng, Yongpei Li, Jianwen Zhou, Li Fan, Tao Wang, Zhihui Deng   +12 more
doaj   +1 more source

Epigenetic activation of secretory phenotypes in senescence by the FOXQ1-SIRT4-GDH signaling

Cell Death and Disease, 2023
Although metabolic reprogramming is characterized as a hallmark of aging, implications of the crucial glutamate dehydrogenase (GDH) in human senescence remain poorly understood.
Xinpei Sun, Qian Li, Yunyi Tang, Wanjin Hu, Gengyao Chen, Hongguang An, Daoyuan Huang, Tanjun Tong, Yu Zhang   +8 more
doaj   +1 more source