Results 31 to 40 of about 10,675,471 (331)
The mitochondrial intermembrane space: the most constricted mitochondrial sub-compartment with the largest variety of protein import pathways [PDF]
Open Biology, 2021 The mitochondrial intermembrane space (IMS) is the most constricted sub-mitochondrial compartment, housing only about 5% of the mitochondrial proteome, and yet is endowed with the largest variability of protein import mechanisms.
Ruairidh Edwards +2 more
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Mitochondrial protein import: Common principles and physiological networks
Biochimica Et Biophysica Acta - Molecular Cell Research, 2013 Peter Rehling, Martin van der Laan
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IMPORT OF PROTEINS INTO MITOCHONDRIA
Annual Review of Genetics, 1991 The biogenesis of mitochondria involves a close interaction between the nucleocytoplasmic and the mitochondrial genetic system. The majority of the mitochondrial proteins are synthesized on cytoplasmic ribosomes and transported into the organelle (1). The mechanism of this protein import has been under debate for many years (e.g., (2,3)).
Glick B, Schatz G
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Molecules, 2021 In human cells, one-third of all polypeptides enter the secretory pathway at the endoplasmic reticulum (ER). The specificity and efficiency of this process are guaranteed by targeting of mRNAs and/or polypeptides to the ER membrane. Cytosolic SRP and its
Pratiti Bhadra +8 more
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Current Opinion in Cell Biology, 1997 The defining feature of eukaryotic organisms is the cell nucleus. All nuclear proteins are synthesized in the cytoplasm and need to be imported through the nuclear pore complexes (NPCs) into the nucleus. Import can be directed by various signals, of which the classical nuclear localization signal (NLS) and the M9 import signal are the best ...
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Membrane Processing and Steady-State Regulation of the Alternative Peroxisomal Import Receptor Pex9p
Frontiers in Cell and Developmental Biology, 2020 Import of peroxisomal matrix proteins with a type 1 peroxisomal targeting signal (PTS1) in Saccharomyces cerevisiae is facilitated by cytosolic import receptors Pex5p and Pex9p. While Pex5p has a broad specificity for all PTS1 proteins independent of the
Markus Rudowitz +2 more
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mBio, 2022 Bacteria exploit a variety of attack strategies to gain dominance within ecological niches. Prominent among these are contact-dependent inhibition (CDI), type VI secretion (T6SS), and bacteriocins.
Iva Atanaskovic +4 more
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The protein import apparatus of chloroplasts [PDF]
, 1993 Routing of cytosolically synthesized precursor proteins into chloroplasts is a specific process which involves a multitude of soluble and membrane components.
Soll, Jürgen +3 more
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Cells, 2023 Regulator of TElomere Length Helicase 1 (RTEL1) is a helicase required for telomere maintenance and genome replication and repair. RTEL1 has been previously shown to participate in the nuclear export of small nuclear RNAs.
Michael Schertzer +5 more
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Import of proteins into mitochondria [PDF]
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1988 Abstract A mounting body of evidence suggests that cytoplasmically synthesized proteins destined to be imported into the mitochondrial interior must at least partly unfold to penetrate across the mitochondrial membranes. During post-translational import, this unfolding process appears to be a major rate-limiting step.
Eilers M, Verner K, Hwang S, Schatz G
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