Results 11 to 20 of about 10,675,471 (331)
Mitochondrial protein import under kinase surveillance
Microbial Cell, 2014 Despite the simplicity of the yeast Saccharomyces cerevisiae,its basic cellular machinery tremendously mirrors that of higher eukaryotic counterparts.
Magdalena Opalińska, Chris Meisinger
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Mitochondrial protein import [PDF]
Journal of Bioenergetics and Biomembranes, 1990 Most polypeptides of mitochondria are imported from the cytosol. Precursor proteins contain targeting and sorting information, often in the form of amino-terminal presequences. Precursors first bind to receptors in the outer membrane. Two putative import receptors have been identified: a 19-kilodalton protein (MOM19) in Neurospora mitochondria, and a ...
Pfanner, Nikolaus, Neupert, Walter
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Definitions, 2020 A homology search using the SECI sequence (1) revealed a significant homology at the protein level with two other yeast genes, SLYI and SLPI (2). These three proteins are involved in protein secretion and intracellular transport in yeast, each at a ...
M. Aalta’” +23 more
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Import of proteins into the peroxisomal matrix [PDF]
Frontiers in Physiology, 2013 Peroxisomes constitute a dynamic compartment in all nucleated cells. They fulfill diverse metabolic tasks in response to environmental changes and cellular demands.
Sohel eHasan +2 more
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Increased mitochondrial protein import and cardiolipin remodelling upon early mtUPR.
PLoS Genetics, 2021 Mitochondrial defects can cause a variety of human diseases and protective mechanisms exist to maintain mitochondrial functionality. Imbalances in mitochondrial proteostasis trigger a transcriptional program, termed mitochondrial unfolded protein ...
Daniel Poveda-Huertes +7 more
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DELE1 tracks perturbed protein import and processing in human mitochondria
Nature Communications, 2022 Protein homeostatic control of mitochondria is key to age-related diseases and organismal decline. However, it is unknown how the diverse types of stress experienced by mitochondria can be integrated and appropriately responded to in human cells. Here we
Evelyn Fessler +2 more
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Types of nuclear localization signals and mechanisms of protein import into the nucleus
Cell communication and signaling : CCS, 2021 Nuclear localization signals (NLS) are generally short peptides that act as a signal fragment that mediates the transport of proteins from the cytoplasm into the nucleus.
Juane Lu +6 more
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Role of the Mitochondrial Protein Import Machinery and Protein Processing in Heart Disease
Frontiers in Cardiovascular Medicine, 2021 Mitochondria are essential organelles for cellular energy production, metabolic homeostasis, calcium homeostasis, cell proliferation, and apoptosis.
Fujie Zhao, Ming-Hui Zou
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Import of mitochondrial proteins [PDF]
Biochemical Society Transactions, 1984 Publisher Summary This chapter describes the structural organization and function of the import systems that mediate protein targeting to mitochondria, and how genetic alterations of these systems contribute to the development of neurodegenerative disorders in humans.
Harmey, Matthew A., Neupert, Walter
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Effect of VIRP1 Protein on Nuclear Import of Citrus Exocortis Viroid (CEVd)
Biomolecules, 2021 Before replicating, Pospiviroidae viroids must move into the plant nucleus. However, the mechanisms of viroid nuclear import are not entirely understood.
Hyesu Seo, Kyunghee Kim, Woong June Park
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