Prediction of GCRV virus-host protein interactome based on structural motif-domain interactions [PDF]
BMC Bioinformatics, 2017 Grass carp hemorrhagic disease, caused by grass carp reovirus (GCRV), is the most fatal causative agent in grass carp aquaculture. Protein-protein interactions between virus and host are one avenue through which GCRV can trigger infection and induce disease.
Aidi Zhang, Libo He, Yaping Wang
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The distribution of GYR- and YLP-like motifs in Drosophila suggests a general role in cuticle assembly and other protein-protein interactions. [PDF]
PLoS ONE, 2010 BACKGROUND: Arthropod cuticle is composed predominantly of a self-assembling matrix of chitin and protein. Genes encoding structural cuticular proteins are remarkably abundant in arthropod genomes, yet there has been no systematic survey of conserved ...
R Scott Cornman
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The conservation pattern of short linear motifs is highly correlated with the function of interacting protein domains [PDF]
BMC Genomics, 2008 Abstract Background Many well-represented domains recognize primary sequences usually less than 10 amino acids in length, called Short Linear Motifs (SLiMs). Accurate prediction of SLiMs has been difficult because they are short (often < 10 amino acids) and highly degenerate.
Wang Yiguo +5 more
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Mechanisms of change in protein architecture [PDF]
, 2011 Proteins are the basic building blocks and functional units in all living organisms. Moreover, differences between species can frequently be explained with differences in their protein complements.
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Concerted upregulation of CLP36 and smooth muscle actin protein expression in human endometrium during decidualization [PDF]
, 2005 The human endometrium prepares for implantation of the blastocyst by reorganization of its whole cellular network. Endometrial stroma cells change their phenotype starting around the 23rd day of the menstrual cycle.
Neumaier-Wagner, Peruka +6 more
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Functional domains of the influenza A virus PB2 protein:identification of NP- and PB1-binding sites [PDF]
, 2004 Influenza virus genomic RNA segments are packaged into ribonucleoprotein (RNP) structures by the PB1, PB2, and PA subunits of an RNA polymerase and a single-strand RNA-binding nucleoprotein (NP).
Poole, Emma +4 more
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PLoS ONE, 2011 PDZ domains recognise short sequence motifs at the extreme C-termini of proteins. A model based on microarray data has been recently published for predicting the binding preferences of PDZ domains to five residue long C-terminal sequences. Here we investigated the potential of this predictor for discovering novel protein interactions that involve PDZ ...
Katja Luck +5 more
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International Journal of Molecular Sciences, 2022 Adhesion and colonization of host cells by pathogenic bacteria depend on protein–protein interactions (PPIs). These interactions are interesting from the pharmacological point of view since new molecules that inhibit host-pathogen PPIs would act as new antimicrobials.
Jordi Gómez Borrego +1 more
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Individual globular domains and domain unfolding visualized in overstretched titin molecules with atomic force microscopy. [PDF]
, 2014 Titin is a giant elastomeric protein responsible for the generation of passive muscle force. Mechanical force unfolds titin's globular domains, but the exact structure of the overstretched titin molecule is not known.
Kellermayer Miklós +5 more
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PLoS Pathogens, 2013 A central challenge in host-pathogen systems biology is the elucidation of general, systems-level principles that distinguish host-pathogen interactions from within-host interactions.
Sara Garamszegi, Eric A Franzosa, Yu Xia
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