Results 31 to 40 of about 1,237,822 (372)

Protein interaction mapping: a Drosophila case study.

Genome Research, 2005
The Drosophila (fruit fly) model system has been instrumental in our current understanding of human biology, development, and diseases. Here, we used a high-throughput yeast two-hybrid (Y2H)-based technology to screen 102 bait proteins from Drosophila ...
E. Formstecher, Sandra Aresta, V. Collura, A. Hamburger, Alain Meil, Alexandra Trehin, Céline Reverdy, V. Betin, Sophie Maire, C. Brun, B. Jacq, M. Arpin, Yohanns Bellaiche, S. Bellusci, P. Benaroch, M. Bornens, R. Chanet, P. Chavrier, O. Delattre, V. Doye, R. Fehon, G. Faye, Thierry Galli, J. Girault, B. Goud, J. de Gunzburg, L. Johannes, M. Junier, Vincent Mirouse, A. Mukherjee, D. Papadopoulo, F. Perez, A. Plessis, Carine Rossé, S. Saule, D. Stoppa-Lyonnet, A. Vincent, M. White, P. Legrain, J. Wojcik, J. Camonis, L. Daviet   +41 more
semanticscholar   +4 more sources

Protein – protein Interaction Mapping of Neurodegenerative Disease

Journal of Survey in Fisheries Sciences, 2023
Significant health risks are associated with neurodegenerative disorders. A variety of age-related factors have developed recently with the increase in the older population.
Ananya Samanta, Semanti Ghosh
semanticscholar   +1 more source

The protein interaction map of bacteriophage lambda [PDF]

BMC Microbiology, 2011
Bacteriophage lambda is a model phage for most other dsDNA phages and has been studied for over 60 years. Although it is probably the best-characterized phage there are still about 20 poorly understood open reading frames in its 48-kb genome. For a complete understanding we need to know all interactions among its proteins.
Rajagopala, Seesandra V., Casjens, Sherwood, Uetz, Peter   +2 more
openaire   +6 more sources

A Protein Interaction Map of the Mitotic Spindle [PDF]

Molecular Biology of the Cell, 2007
The mitotic spindle consists of a complex network of proteins that segregates chromosomes in eukaryotes. To strengthen our understanding of the molecular composition, organization, and regulation of the mitotic spindle, we performed a system-wide two-hybrid screen on 94 proteins implicated in spindle function in Saccharomyces cerevisiae. We report 604
Wong, Jonathan, Nakajima, Yuko, Westermann, Stefan, Shang, Ching, Kang, Jung-Seog, Goodner, Crystal, Houshmand, Pantea, Fields, Stanley, Chan, Clarence S.M., Drubin, David, Barnes, Georjana, Hazbun, Tony R   +11 more
openaire   +5 more sources

Mapping protein–DNA interactions with DiMeLo-seq [PDF]

Nature Protocols, 2022
AbstractWe recently developedDirectedMethylation withLong-readsequencing (DiMeLo-seq) to map protein-DNA interactions genome wide. DiMeLo-seq is capable of mapping multiple interaction sites on single DNA molecules, profiling protein binding in the context of endogenous DNA methylation, identifying haplotype specific protein-DNA interactions, and ...
Annie Maslan, Nicolas Altemose, Reet Mishra, Jeremy Marcus, Lucy D. Brennan, Kousik Sundararajan, Gary Karpen, Aaron F. Straight, Aaron Streets   +8 more
openaire   +3 more sources

Mapping of protein-protein interaction sites in the plant-type [2Fe-2S] ferredoxin. [PDF]

PLoS ONE, 2011
Knowing the manner of protein-protein interactions is vital for understanding biological events. The plant-type [2Fe-2S] ferredoxin (Fd), a well-known small iron-sulfur protein with low redox potential, partitions electrons to a variety of Fd-dependent ...
Haruka Kameda, Kei Hirabayashi, Kei Wada, Keiichi Fukuyama   +3 more
doaj   +1 more source

A protein interaction map of the LSU processome [PDF]

Genes & Development, 2015
Maturation of the large ribosomal subunit (LSU) in eukaryotes is a complex and highly coordinated process that requires the concerted action of a large, dynamic, ribonucleoprotein complex, the LSU processome. While we know that >80 ribosome biogenesis factors are required throughout the course of LSU assembly, little is known about how these factors
J. Michael Charette, Kathleen L. McCann, Nicholas G. Vincent, Susan J. Baserga   +3 more
openaire   +2 more sources

Reconstructing genome-wide protein-protein interaction networks using multiple strategies with homologous mapping. [PDF]

PLoS ONE, 2015
BACKGROUND:One of the crucial steps toward understanding the biological functions of a cellular system is to investigate protein-protein interaction (PPI) networks.
Yu-Shu Lo, Sing-Han Huang, Yong-Chun Luo, Chun-Yu Lin, Jinn-Moon Yang   +4 more
doaj   +1 more source

A Rice Kinase-Protein Interaction Map     [PDF]

Plant Physiology, 2008
AbstractPlants uniquely contain large numbers of protein kinases, and for the vast majority of the 1,429 kinases predicted in the rice (Oryza sativa) genome, little is known of their functions. Genetic approaches often fail to produce observable phenotypes; thus, new strategies are needed to delineate kinase function.
Ding, Xiaodong, Richter, Todd, Chen, Mei, Fujii, Hiroaki, Seo, Young Su, Xie, Mingtang, Zheng, Xianwu, Kanrar, Siddhartha, Stevenson, Rebecca A, Dardick, Christopher, Li, Ying, Jiang, Hao, Zhang, Yan, Yu, Fahong, Bartley, Laura E, Chern, Mawsheng, Bart, Rebecca, Chen, Xiuhua, Zhu, Lihuang, Farmerie, William G, Gribskov, Michael, Zhu, Jian-Kang, Fromm, Michael E, Ronald, Pamela C, Song, Wen-Yuan   +24 more
openaire   +4 more sources

Pan-cancer mapping of differential protein-protein interactions [PDF]

Scientific Reports, 2020
AbstractDeciphering the variations in the protein interactome is required to reach a systems-level understanding of tumorigenesis. To accomplish this task, we have considered the clinical and transcriptome data on >6000 samples from The Cancer Genome Atlas for 12 different cancers.
Raghu Sinha, Beste Turanli, Beste Turanli, Gizem Gulfidan, Kazim Yalcin Arga, Hande Beklen   +5 more
openaire   +6 more sources