Results 21 to 30 of about 7,803,058 (302)

Reconstructing genome-wide protein-protein interaction networks using multiple strategies with homologous mapping. [PDF]

PLoS ONE, 2015
BACKGROUND:One of the crucial steps toward understanding the biological functions of a cellular system is to investigate protein-protein interaction (PPI) networks.
Yu-Shu Lo, Sing-Han Huang, Yong-Chun Luo, Chun-Yu Lin, Jinn-Moon Yang   +4 more
doaj   +1 more source

A Rice Kinase-Protein Interaction Map     [PDF]

Plant Physiology, 2008
AbstractPlants uniquely contain large numbers of protein kinases, and for the vast majority of the 1,429 kinases predicted in the rice (Oryza sativa) genome, little is known of their functions. Genetic approaches often fail to produce observable phenotypes; thus, new strategies are needed to delineate kinase function.
Ding, Xiaodong, Richter, Todd, Chen, Mei, Fujii, Hiroaki, Seo, Young Su, Xie, Mingtang, Zheng, Xianwu, Kanrar, Siddhartha, Stevenson, Rebecca A, Dardick, Christopher, Li, Ying, Jiang, Hao, Zhang, Yan, Yu, Fahong, Bartley, Laura E, Chern, Mawsheng, Bart, Rebecca, Chen, Xiuhua, Zhu, Lihuang, Farmerie, William G, Gribskov, Michael, Zhu, Jian-Kang, Fromm, Michael E, Ronald, Pamela C, Song, Wen-Yuan   +24 more
openaire   +3 more sources

Detecting Mutually Exclusive Interactions in Protein-Protein Interaction Maps

PLoS ONE, 2012
Comprehensive protein interaction maps can complement genetic and biochemical experiments and allow the formulation of new hypotheses to be tested in the system of interest. The computational analysis of the maps may help to focus on interesting cases and thereby to appropriately prioritize the validation experiments.
Carmen Sanchez Claros, TRAMONTANO, ANNA
openaire   +9 more sources

The protein interaction map of bacteriophage lambda [PDF]

BMC Microbiology, 2011
Bacteriophage lambda is a model phage for most other dsDNA phages and has been studied for over 60 years. Although it is probably the best-characterized phage there are still about 20 poorly understood open reading frames in its 48-kb genome. For a complete understanding we need to know all interactions among its proteins.
Rajagopala, Seesandra V., Casjens, Sherwood, Uetz, Peter   +2 more
openaire   +5 more sources

Proteome-wide prediction and analysis of the Cryptosporidium parvum protein–protein interaction network through integrative methods

Computational and Structural Biotechnology Journal, 2022
As one of the most studied Apicomplexan parasite Cryptosporidium, Cryptosporidium parvum (C. parvum) causes worldwide serious diarrhea disease cryptosporidiosis, which can be deadly to immunodeficiency individuals, newly born children, and animals ...
Panyu Ren, Xiaodi Yang, Tianpeng Wang, Yunpeng Hou, Ziding Zhang   +4 more
doaj   +1 more source

Evolutionarily conserved herpesviral protein interaction networks. [PDF]

, 2009
Herpesviruses constitute a family of large DNA viruses widely spread in vertebrates and causing a variety of different diseases. They possess dsDNA genomes ranging from 120 to 240 kbp encoding between 70 to 170 open reading frames. We previously reported
Bandyopadhyay, Sourav, Baiker Armin, Brunn, Albrecht von, Dong, Yu-An, Silpa Suthram, Haas, Jürgen, Dietlind Rose, von Brunn, Albrecht, Rutenberg Christiane, Ralf Zimmer, Bailer Susanne M., Schmidt, Tina, Stellberger Thorsten, Rose, Dietlind, Haas Jürgen, Titz Björn, Zimmer, Ralf, Christine Zeretzke, Mareike Uhlmann, Seesandra V Rajagopala, Manfred Koegl, Boulet Hélène, Koegl, Manfred, Susanne M Bailer, Trey Ideker, Baiker, Armin, Fossum, Even, Zeretzke, Christine, Peter Uetz, Schmidt Tina, Koegl Manfred, Thorsten Stellberger, Hélène Boulet, Kraus Theo, Armin Baiker, Tina Schmidt, Ideker, Trey, Koszinowski, Ulrich, Sourav Bandyopadhyay, Suthram Silpa, Björn Titz, Boulet, Hélène, Koszinowski Ulrich, Rajagopala, Seesandra V., Caroline C Friedel, Bailer, Susanne M, Rajagopala, Seesandra V, Dong Yu-An, Even Fossum, Bandyopadhyay Sourav, Bailer, Susanne M., Uhlmann, Mareike, Haas, Jürgen G., Ulrich Koszinowski, Uhlmann Mareike, Uetz Peter, Zimmer Ralf, Christiane Rutenberg, Friedel, Caroline C., Friedel, Caroline C, Titz, Björn, Koszinowski, Ulrich H., Rajagopala Seesandra V., Titz, Bjoern, Haas, Juergen, Ideker Trey, Albrecht von Brunn, Suthram, Silpa, Zeretzke Christine, Rutenberg, Christiane, Kraus, Theo, Jürgen Haas, Friedel Caroline C., Stellberger, Thorsten, Theo Kraus, Yu-An Dong, Rose Dietlind, Fossum Even, Uetz, Peter, von Brunn Albrecht   +79 more
core   +1 more source

Prediction of protein-protein interaction types using association rule based classification [PDF]

, 2009
This article has been made available through the Brunel Open Access Publishing Fund - Copyright @ 2009 Park et alBackground: Protein-protein interactions (PPI) can be classified according to their characteristics into, for example obligate or transient ...
José A Reyes, Kim, JW, Kim, S, Kim Ji, Sangsoo Kim, Gilbert, D, Park, SH, Reyes José A, Reyes, JA, Kim Sangsoo, Park Sung, Ji Kim, David R Gilbert, Gilbert David R, Sung Park   +14 more
core   +1 more source

A Map of Interactions between the Proteins of a Retrotransposon [PDF]

Journal of Virology, 1998
ABSTRACTThe yeast two-hybrid system and in vitro binding assays were used to characterize 54 potential interactions between the proteins of Tf1, an LTR-retrotransposon found inSchizosaccharomyces pombe. The Tf1 integrase (IN) protein was found to interact strongly with itself and not with other control proteins.
S J, Steele, H L, Levin
openaire   +2 more sources

Identification of Breast Cancer Biomarkers by Constructing Protein-Protein Interaction and miRNAs-mRNAs Networks [PDF]

Middle East Journal of Cancer
Background: In cancer-related diseases, early detection and control of disease progression are very important for successful treatment. Breast cancer is a significant problem due to its high mortality rate in the female population worldwide. By the early
Azizeh Asadzadeh, Bita Behboodian, Parsa Bernoos, Masoumeh Shojaei Barjouei   +3 more
doaj   +1 more source

Mapping Transcriptome Data to Protein–Protein Interaction Networks of Inflammatory Bowel Diseases Reveals Disease-Specific Subnetworks

Frontiers in Genetics, 2021
Inflammatory bowel disease (IBD) is the common name for chronic disorders associated with the inflammation of the gastrointestinal tract. IBD is triggered by environmental factors in genetically susceptible individuals and has a significant number of ...
Sefika Feyza Maden, Saliha Ece Acuner
doaj   +1 more source