Results 31 to 40 of about 1,208,117 (287)

Hybridized distance- and contact-based hierarchical structure modeling for folding soluble and membrane proteins.

open access: yesPLoS Computational Biology, 2021
Crystallography and NMR system (CNS) is currently a widely used method for fragment-free ab initio protein folding from inter-residue distance or contact maps. Despite its widespread use in protein structure prediction, CNS is a decade-old macromolecular
Rahmatullah Roche   +2 more
doaj   +1 more source

MAPping out distribution routes for kinesin couriers [PDF]

open access: yes, 2013
In the crowded environment of eukaryotic cells, diffusion is an inefficient distribution mechanism for cellular components. Long-distance active transport is required and is performed by molecular motors including kinesins.
*Ackmann   +235 more
core   +1 more source

Protein-protein interaction map inference using interacting domain profile pairs [PDF]

open access: yesBioinformatics, 2001
Abstract A number of predictive methods have been designed to predict protein interaction from sequence or expression data. On the experimental front, however, high-throughput proteomics technologies are starting to yield large volumes of protein-protein interaction data.
J, Wojcik, V, Schächter
openaire   +2 more sources

Bioinformatics Investigation and Contribution of Other Chromosomes Besides Chromosome 21 in the Risk of Down Syndrome Development

open access: yesBasic and Clinical Neuroscience, 2021
Introduction: Down syndrome as a genetic disorder is a popular research topic in molecular studies. One way to study Down syndrome is via bioinformatics.
Mona Zamanian Azodi   +3 more
doaj  

A human MAP kinase interactome. [PDF]

open access: yes, 2010
Mitogen-activated protein kinase (MAPK) pathways form the backbone of signal transduction in the mammalian cell. Here we applied a systematic experimental and computational approach to map 2,269 interactions between human MAPK-related proteins and other ...
A Friedman   +51 more
core   +3 more sources

Drosophila Protein interaction Map (DPiM) [PDF]

open access: yesFly, 2012
Proteins perform essential cellular functions as part of protein complexes, often in conjunction with RNA, DNA, metabolites and other small molecules. The genome encodes thousands of proteins but not all of them are expressed in every cell type; and expressed proteins are not active at all times.
Guruharsha, K.G.   +6 more
openaire   +3 more sources

Fibrinogen Dysregulation is a Prominent Process in Fatal Conditions of COVID-19 Infection; a Proteomic Analysis

open access: yesArchives of Academic Emergency Medicine, 2021
Introduction: Molecular pathophysiology of COVID-19 is not completely known. Expression changes in patients' plasma proteins have revealed new information about the disease.
Mostafa Rezaei-Tavirani   +5 more
doaj   +1 more source

A strategy for constructing large protein interaction maps using the yeast two-hybrid system: regulated expression arrays and two-phase mating.

open access: yesGenome Research, 2003
Maps representing the binary interactions among proteins have become valuable tools for understanding how proteins work together to mediate biological processes.
J. Zhong   +4 more
semanticscholar   +1 more source

Immune system and zinc are associated with recurrent aphthous stomatitis. An assessment using a network-based approach.

open access: yesJournal of Oral Research, 2017
Objective: The aim of this research was to identify genes, proteins and processes from the biomedical information published on recurrent aphthous stomatitis (RAS) using network-based foci.
César Rivera
doaj   +1 more source

Crystal Structure of the Cysteine-Rich Domain of Mannose Receptor Complexed with a Sulfated Carbohydrate Ligand [PDF]

open access: yes, 2000
The macrophage and epithelial cell mannose receptor (MR) binds carbohydrates on foreign and host molecules. Two portions of MR recognize carbohydrates: tandemly arranged C-type lectin domains facilitate carbohydrate-dependent macrophage uptake of ...
Bjorkman, Pamela J.   +6 more
core   +2 more sources

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