Results 21 to 30 of about 8,260,919 (293)
The protein interaction map of bacteriophage lambda [PDF]
BMC Microbiology, 2011 Bacteriophage lambda is a model phage for most other dsDNA phages and has been studied for over 60 years. Although it is probably the best-characterized phage there are still about 20 poorly understood open reading frames in its 48-kb genome. For a complete understanding we need to know all interactions among its proteins.
Rajagopala, Seesandra V. +2 more
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A Rice Kinase-Protein Interaction Map [PDF]
Plant Physiology, 2008 AbstractPlants uniquely contain large numbers of protein kinases, and for the vast majority of the 1,429 kinases predicted in the rice (Oryza sativa) genome, little is known of their functions. Genetic approaches often fail to produce observable phenotypes; thus, new strategies are needed to delineate kinase function.
Ding, Xiaodong +24 more
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Identification of Key Genes and Pathways in Peripheral Blood Mononuclear Cells of Type 1 Diabetes Mellitus by Integrated Bioinformatics Analysis [PDF]
Diabetes & Metabolism Journal, 2022 Background The onset and progression of type 1 diabetes mellitus (T1DM) is closely related to autoimmunity. Effective monitoring of the immune system and developing targeted therapies are frontier fields in T1DM treatment.
Xing Li +6 more
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A protein interaction map of the LSU processome [PDF]
Genes & Development, 2015 Maturation of the large ribosomal subunit (LSU) in eukaryotes is a complex and highly coordinated process that requires the concerted action of a large, dynamic, ribonucleoprotein complex, the LSU processome. While we know that >80 ribosome biogenesis factors are required throughout the course of LSU assembly, little is known about how these factors
McCann, Kathleen L. +3 more
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Prediction of Coffee Effects in Rats with Healthy and NAFLD Conditions Based on Protein-Protein Interaction Network Analysis [PDF]
Research Journal of Pharmacognosy, 2019 Background and objectives: Non-alcoholic fatty liver disease (NAFLD) is a common liver condition. On the other hand, coffee consumption has shown promising for gastrointestinal diseases.
Majid Rezaei-Tavirani +4 more
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Biomolecules, 2023 Elucidating protein–ligand interaction is crucial for studying the function of proteins and compounds in an organism and critical for drug discovery and design.
Nabin Giri, Jianlin Cheng
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A Map of Interactions between the Proteins of a Retrotransposon [PDF]
Journal of Virology, 1998 ABSTRACTThe yeast two-hybrid system and in vitro binding assays were used to characterize 54 potential interactions between the proteins of Tf1, an LTR-retrotransposon found inSchizosaccharomyces pombe. The Tf1 integrase (IN) protein was found to interact strongly with itself and not with other control proteins.
S J, Steele, H L, Levin
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Protein-protein interaction map for yeast TFIID [PDF]
Nucleic Acids Research, 2003 A major rate-limiting step in transcription initiation by RNA polymerase II is recognition and binding of the TATA element by the transcription factor TFIID. TFIID is composed of TATA binding protein (TBP) and approximately a dozen TBP-associated factors (TAFs).
Gayatri, Yatherajam +3 more
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Pan-cancer mapping of differential protein-protein interactions [PDF]
Scientific Reports, 2020 AbstractDeciphering the variations in the protein interactome is required to reach a systems-level understanding of tumorigenesis. To accomplish this task, we have considered the clinical and transcriptome data on >6000 samples from The Cancer Genome Atlas for 12 different cancers.
Gulfidan, Gizem +4 more
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Functional maps of protein complexes from quantitative genetic interaction data.
PLoS Computational Biology, 2008 Recently, a number of advanced screening technologies have allowed for the comprehensive quantification of aggravating and alleviating genetic interactions among gene pairs.
Sourav Bandyopadhyay +3 more
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