Results 11 to 20 of about 434,956 (254)
Cost-Effective Mapping of Genetic Interactions in Mammalian Cells
Frontiers in Genetics, 2021 Comprehensive maps of genetic interactions in mammalian cells are daunting to construct because of the large number of potential interactions, ~ 2 × 108 for protein coding genes. We previously used co-inheritance of distant genes from published radiation
Arshad H. Khan, Desmond J. Smith
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Mapping protein–DNA interactions with DiMeLo-seq [PDF]
Nature Protocols, 2022 Abstract We recently developed Di rected Me thylation with Lo ng-read seq uencing (DiMeLo-seq) to map protein-DNA interactions genome wide.
Annie Maslan +8 more
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The protein interaction map of bacteriophage lambda [PDF]
BMC Microbiology, 2011 Bacteriophage lambda is a model phage for most other dsDNA phages and has been studied for over 60 years. Although it is probably the best-characterized phage there are still about 20 poorly understood open reading frames in its 48-kb genome. For a complete understanding we need to know all interactions among its proteins.
Rajagopala, Seesandra V. +2 more
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Advanced Biomedical Research, 2022 Background: Tenascin-C (TNC) is a large glycoprotein of the extracellular matrix which associated with poor clinical outcomes in several malignancies. TNC over-expression is repeatedly observed in several cancer tissues and promotes several processes in ...
Ilnaz Rahimmanesh +2 more
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Frontiers in Physiology, 2020 The arteriovenous fistula (AVF) is the first choice for vascular access for hemodialysis of renal failure patients. Venous remodeling after exposure to high fistula flow is important for AVF to mature but the mechanism underlying remodeling is still ...
Kong Jie +13 more
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A Rice Kinase-Protein Interaction Map [PDF]
Plant Physiology, 2008 AbstractPlants uniquely contain large numbers of protein kinases, and for the vast majority of the 1,429 kinases predicted in the rice (Oryza sativa) genome, little is known of their functions. Genetic approaches often fail to produce observable phenotypes; thus, new strategies are needed to delineate kinase function.
Ding, Xiaodong +24 more
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A protein interaction map of the LSU processome [PDF]
Genes & Development, 2015 Maturation of the large ribosomal subunit (LSU) in eukaryotes is a complex and highly coordinated process that requires the concerted action of a large, dynamic, ribonucleoprotein complex, the LSU processome. While we know that >80 ribosome biogenesis factors are required throughout the course of LSU assembly, little is known about how these factors
McCann, Kathleen L. +3 more
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A Map of Interactions between the Proteins of a Retrotransposon [PDF]
Journal of Virology, 1998 ABSTRACTThe yeast two-hybrid system and in vitro binding assays were used to characterize 54 potential interactions between the proteins of Tf1, an LTR-retrotransposon found inSchizosaccharomyces pombe. The Tf1 integrase (IN) protein was found to interact strongly with itself and not with other control proteins.
S J, Steele, H L, Levin
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Prediction of Coffee Effects in Rats with Healthy and NAFLD Conditions Based on Protein-Protein Interaction Network Analysis [PDF]
Research Journal of Pharmacognosy, 2019 Background and objectives: Non-alcoholic fatty liver disease (NAFLD) is a common liver condition. On the other hand, coffee consumption has shown promising for gastrointestinal diseases.
Majid Rezaei-Tavirani +4 more
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Biomolecules, 2023 Elucidating protein–ligand interaction is crucial for studying the function of proteins and compounds in an organism and critical for drug discovery and design.
Nabin Giri, Jianlin Cheng
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