Results 11 to 20 of about 8,260,919 (293)
Comparison of human protein-protein interaction maps [PDF]
Bioinformatics, 2007 : Large-scale mappings of protein-protein interactions have started to give us new views of the complex molecular mechanisms inside a cell. After initial projects to systematically map protein interactions in model organisms such as yeast, worm and fly ...
Erich Wanker +3 more
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Improving the resolution of interaction maps: A middleground between high-resolution complexes and genome-wide interactomes [PDF]
, 2013 Protein-protein interactions are ubiquitous in Biology and therefore central to understand living organisms. In recent years, large-scale studies have been undertaken to describe, at least partially, protein-protein interaction maps or interactomes for a
Mora, Joan Segura
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PLoS Genetics, 2021 The perturbations of protein-protein interactions (PPIs) were found to be the main cause of cancer. Previous PPI prediction methods which were trained with non-disease general PPI data were not compatible to map the PPI network in cancer.
Jiajun Qiu +4 more
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Identifying Potential Biomarkers in Colorectal Cancer and Developing Non-invasive Diagnostic Models Using Bioinformatics Approaches [PDF]
Avicenna Journal of Medical Biochemistry, 2020 Background: Colorectal cancer (CRC) is one of the most frequent causes of gastrointestinal tumors. Due to the invasiveness of the current diagnostic methods, there is an urgent need to develop non-invasive diagnostic approaches for CRC.
Massoud Saidijam +2 more
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Imputation of quantitative genetic interactions in epistatic MAPs by interaction propagation matrix completion [PDF]
, 2014 A popular large-scale gene interaction discovery platform is the Epistatic Miniarray Profile (E-MAP). E-MAPs benefit from quantitative output, which makes it possible to detect subtle interactions.
Zupan, Blaz, Zitnik, Marinka
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A Protein Interaction Map of the Mitotic Spindle [PDF]
Molecular Biology of the Cell, 2007 The mitotic spindle consists of a complex network of proteins that segregates chromosomes in eukaryotes. To strengthen our understanding of the molecular composition, organization, and regulation of the mitotic spindle, we performed a system-wide two-hybrid screen on 94 proteins implicated in spindle function in Saccharomyces cerevisiae. We report 604
Wong, Jonathan +11 more
openaire +3 more sources
Cost-Effective Mapping of Genetic Interactions in Mammalian Cells
Frontiers in Genetics, 2021 Comprehensive maps of genetic interactions in mammalian cells are daunting to construct because of the large number of potential interactions, ~ 2 × 108 for protein coding genes. We previously used co-inheritance of distant genes from published radiation
Arshad H. Khan, Desmond J. Smith
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Mapping protein–DNA interactions with DiMeLo-seq [PDF]
Nature Protocols, 2022 Abstract We recently developed Di rected Me thylation with Lo ng-read seq uencing (DiMeLo-seq) to map protein-DNA interactions genome wide.
Annie Maslan +8 more
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Frontiers in Physiology, 2020 The arteriovenous fistula (AVF) is the first choice for vascular access for hemodialysis of renal failure patients. Venous remodeling after exposure to high fistula flow is important for AVF to mature but the mechanism underlying remodeling is still ...
Kong Jie +13 more
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Advanced Biomedical Research, 2022 Background: Tenascin-C (TNC) is a large glycoprotein of the extracellular matrix which associated with poor clinical outcomes in several malignancies. TNC over-expression is repeatedly observed in several cancer tissues and promotes several processes in ...
Ilnaz Rahimmanesh +2 more
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