Results 11 to 20 of about 435,247 (293)
Comparison of human protein-protein interaction maps [PDF]
Bioinformatics, 2007 MOTIVATION: Large-scale mappings of protein-protein interactions have started to give us new views of the complex molecular mechanisms inside a cell. After initial projects to systematically map protein interactions in model organisms such as yeast, worm
Chaurasia, G. +2 more
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Cluster-based assessment of protein-protein interaction confidence [PDF]
BMC Bioinformatics, 2012 Background Protein-protein interaction networks are key to a systems-level understanding of cellular biology. However, interaction data can contain a considerable fraction of false positives. Several methods have been proposed to assess the confidence of
Kamburov Atanas +3 more
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A Protein Interaction Map of the Mitotic Spindle [PDF]
Molecular Biology of the Cell, 2007 The mitotic spindle consists of a complex network of proteins that segregates chromosomes in eukaryotes. To strengthen our understanding of the molecular composition, organization, and regulation of the mitotic spindle, we performed a system-wide two-hybrid screen on 94 proteins implicated in spindle function in Saccharomyces cerevisiae. We report 604
Wong, Jonathan +11 more
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Mapping protein–DNA interactions with DiMeLo-seq [PDF]
Nature Protocols, 2022 Abstract We recently developed Di rected Me thylation with Lo ng-read seq uencing (DiMeLo-seq) to map protein-DNA interactions genome wide.
Annie Maslan +8 more
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Advanced Biomedical Research, 2022 Background: Tenascin-C (TNC) is a large glycoprotein of the extracellular matrix which associated with poor clinical outcomes in several malignancies. TNC over-expression is repeatedly observed in several cancer tissues and promotes several processes in ...
Ilnaz Rahimmanesh +2 more
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The protein interaction map of bacteriophage lambda [PDF]
BMC Microbiology, 2011 Bacteriophage lambda is a model phage for most other dsDNA phages and has been studied for over 60 years. Although it is probably the best-characterized phage there are still about 20 poorly understood open reading frames in its 48-kb genome. For a complete understanding we need to know all interactions among its proteins.
Rajagopala, Seesandra V. +2 more
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Frontiers in Physiology, 2020 The arteriovenous fistula (AVF) is the first choice for vascular access for hemodialysis of renal failure patients. Venous remodeling after exposure to high fistula flow is important for AVF to mature but the mechanism underlying remodeling is still ...
Kong Jie +13 more
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A Rice Kinase-Protein Interaction Map [PDF]
Plant Physiology, 2008 AbstractPlants uniquely contain large numbers of protein kinases, and for the vast majority of the 1,429 kinases predicted in the rice (Oryza sativa) genome, little is known of their functions. Genetic approaches often fail to produce observable phenotypes; thus, new strategies are needed to delineate kinase function.
Ding, Xiaodong +24 more
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Imputation of quantitative genetic interactions in epistatic MAPs by interaction propagation matrix completion [PDF]
, 2014 A popular large-scale gene interaction discovery platform is the Epistatic Miniarray Profile (E-MAP). E-MAPs benefit from quantitative output, which makes it possible to detect subtle interactions.
Marinka Žitnik +3 more
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A protein interaction map of the LSU processome [PDF]
Genes & Development, 2015 Maturation of the large ribosomal subunit (LSU) in eukaryotes is a complex and highly coordinated process that requires the concerted action of a large, dynamic, ribonucleoprotein complex, the LSU processome. While we know that >80 ribosome biogenesis factors are required throughout the course of LSU assembly, little is known about how these factors
McCann, Kathleen L. +3 more
openaire +2 more sources