Results 141 to 150 of about 4,093 (168)

Bacterial lipoate protein ligases rescue lipoylation and respiration deficiency in mammals

SummaryHuman lipoylation pathway deficiencies caused by LIPT2/LIAS/LIPT1 gene mutations lead to inherited metabolic disorders characterized by severe defects of mitochondrial energy and amino acids metabolism. Patients with such mutations suffer from hyperlactic acidemia, encephalopathy, hypotonia and early death. So far there is no effective treatment.
Zhijuan Hu, Junru Yu, Ziwei Liu, Min Jiang, An-Ping Zeng   +4 more
openaire   +1 more source

Faculty Opinions recommendation of Copper induces cell death by targeting lipoylated TCA cycle proteins.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2022
Yi Lu, Weijie Guo
openaire   +2 more sources

Site-specific protein lipoylation analysis via aldehyde-acetal probe labelling and reversible enrichment (DA-Lipo)

Chemical Communications
A streamlined method for site-specific identification of protein lipoylation via aldehyde-acetal probe labeling and reversible hydrazine chemistry enrichment.
Tianqi Jiang, Xuyang Yue, Jiaying Li, Enming Miao, Huihui Wan, Gege Gu, Xuwei Chen, Mingliang Ye, Hongqiang Qin   +8 more
openaire   +1 more source

Mechanisms, regulation and functions of the unfolded protein response

Nature Reviews Molecular Cell Biology, 2020
Claudio Hetz, Kezhong Zhang, Randal J Kaufman   +2 more
exaly  

Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing

Nature Reviews Molecular Cell Biology, 2021
Simon Alberti, Anthony A Hyman
exaly  

Assay for protein lipoylation reaction.

Methods in enzymology, 1995
K, Fujiwara, K, Okamura-Ikeda, Y, Motokawa   +2 more
openaire   +1 more source

The mechanisms of integral membrane protein biogenesis

Nature Reviews Molecular Cell Biology, 2021
Ramanujan Shankar Hegde, Robert J Keenan
exaly  

Derivatization with fatty acids in peptide and protein drug discovery

Nature Reviews Drug Discovery, 2022
Peter Kurtzhals, Søren Østergaard, Erica Nishimura   +2 more
exaly  

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

Nature Reviews Molecular Cell Biology, 2012
Claudio Hetz
exaly  

Functions and mechanisms of non-histone protein acetylation

Nature Reviews Molecular Cell Biology, 2018
Takeo Narita, Chunaram Choudhary
exaly