Results 161 to 170 of about 92,071 (194)
Some of the next articles are maybe not open access.
Mathematics of protein pathological misfolding
Mathematical Biosciences, 2007"Protein folding is defined as a process by which a polypeptide chain performs a search in conformational space with the objective of achieving the so-called native conformation to global free-energy minimum under a given set of physiochemical conditions of the medium." Misfolding then, is the process by which this objective is not achieved.
openaire +2 more sources
2010
Protein misfolding, which literally means “incorrect folding” is associated with a number of pathological states in humans, collectively termed protein misfolding diseases. In some cases the disease arises because a specific protein is no longer functional when adopting a misfolded state or undergoes a severe trafficking impairment (loss of function ...
CAMPIONI, SILVIA +2 more
openaire +1 more source
Protein misfolding, which literally means “incorrect folding” is associated with a number of pathological states in humans, collectively termed protein misfolding diseases. In some cases the disease arises because a specific protein is no longer functional when adopting a misfolded state or undergoes a severe trafficking impairment (loss of function ...
CAMPIONI, SILVIA +2 more
openaire +1 more source
Mechanisms, regulation and functions of the unfolded protein response
Nature Reviews Molecular Cell Biology, 2020Claudio Hetz +2 more
exaly
Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing
Nature Reviews Molecular Cell Biology, 2021Simon Alberti, Anthony A Hyman
exaly
The mechanisms of integral membrane protein biogenesis
Nature Reviews Molecular Cell Biology, 2021Ramanujan Shankar Hegde, Robert J Keenan
exaly