Results 181 to 190 of about 3,647,798 (263)

Diabetic Peripheral Neuropathy With Low Appendicular Muscle Mass Is Associated With Osteoporosis, Falls, and Fractures

Journal of Diabetes, Volume 18, Issue 11, November 2026.
Diabetics have higher risks of osteoporosis, falls, and fractures; higher grip strength predicts lower risks. In both cross‐sectional and longitudinal data, diabetic patients with both peripheral neuropathy and low appendicular muscle mass have the highest risks of osteoporosis and falls.
Biao Zheng, Yongze Zhang, Dan Liang, Ximei Shen, Lingning Huang, Fengying Zhao, Sunjie Yan   +6 more
wiley   +1 more source

Light Chain Monoclonal Gammopathy of Undetermined Significance: Diagnosis, Biology, and Clinical Management

European Journal of Haematology, Volume 117, Issue 5, Page 1159-1167, November 2026.
ABSTRACT Light chain monoclonal gammopathy of undetermined significance (LC‐MGUS) is defined by an abnormal serum free light chain ratio and elevated involved light chain in the absence of a detectable immunoglobulin heavy chain on immunofixation and of end‐organ damage attributable to a plasma cell disorder.
Sigurður Yngvi Kristinsson, Thórir Einarsson Long, Sigrún Thorsteinsdóttir   +2 more
wiley   +1 more source

Neurodegeneration Through the Lens of Bioinformatics Approaches: Computational Mechanisms of Protein Misfolding. [PDF]

Int J Mol Sci
Hassan M, Shahzadi S, Moustafa AA, Kloczkowski A.   +3 more
europepmc   +1 more source

Auxin response and PIN‐mediated transport in chlorophyte algae

Journal of Integrative Plant Biology, Volume 68, Issue 11, Page 3947-3961, November 2026.
Like multicellular plants, green algae respond to auxin and move it across their cells. However, their PIN‐like proteins do not act like plant auxin exporters, suggesting that basic auxin transport evolved early and specialized directional transport appeared later in plant evolution.
Adrijana Smoljan, Sarah Koutnik‐Abele, Dmitrii Vladimirtsev, Petr Klíma, Anita Bírošíková, Yuzhou Zhang, Jack Merrin, Maximilian Schuster, Katarina Kurtović, Ulrich Z. Hammes, Jan Petrášek, Jiří Friml   +11 more
wiley   +1 more source

Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules

Plant Biotechnology Journal, Volume 24, Issue 11, Page 5616-5630, November 2026.
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan, Hiroko Miyadera, Kaho Oka, Kohei Ishikawa, Toshiya Kobayashi, Misaki Kobayashi, Mitsunori Shiroishi, Emiko Noguchi, Kenji Miura   +8 more
wiley   +1 more source

Distinct Molten‐Globule Conformations in an Interacting Protein Domain Resolved by 19F NMR of Fluoroproline Residues

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
Modifying the conformational ensemble of “molten‐globule” protein by the site‐specific incorporation of stereoisomeric 4‐fluoroproline residues modulated its binding affinity and aggregation behavior. 19F NMR spectroscopy enabled the detection of key interactions responsible for structural and dynamic changes. ABSTRACT Recently, the application of deep
Abir Ben Bouzayene, Mariam Sai, Alexis Jouin, Yves Nominé, Vladimir Torbeev, Bruno Kieffer   +5 more
wiley   +2 more sources

Design Principles of Plant Thermotolerance: Integrating Photosynthesis, Reproduction, and Field Resilience in a Warming Climate

Plant, Cell &Environment, Volume 49, Issue 11, Page 8735-8750, November 2026.
ABSTRACT Global food security is increasingly threatened by climate change, as rising temperatures compromise the yields of major staple crops, including wheat, rice, and maize. Enhancing plant thermotolerance has therefore become a critical priority for sustaining agricultural productivity.
Yuchen Qu, Wataru Yamori
wiley   +1 more source

Farnesyltransferase Enables Modular Assembly of Dual‐Functional Nanobody Conjugates for in Vivo Imaging of Inflammation

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
A modular farnesyltransferase‐based chemoenzymatic platform enables fast, site‐specific labeling of nanobodies for PET imaging of inflammation. CD11b‐targeted PET agents selectively image myeloid‐driven inflammation, while CD45‐targeted PET agents provide sensitive whole‐body immune mapping.
Sneha Venkatachalapathy, Yoon Ho Lee, Ali Salehi Farid, Heydar Moravej, Sina Djafari Rouhani, Jennifer E. Rowley, Mohammad Rashidian, Mark D. Distefano   +7 more
wiley   +2 more sources

Targeting endoplasmic reticulum stress and protein misfolding in schizophrenia: the emerging promise of sigma-1 receptor agonists. [PDF]

Psychopharmacology (Berl)
Ahmed MK, Abdou K, Ibrahim WW, Mohamed AF, El-Boghdady NA.   +4 more
europepmc   +1 more source

Sorghum Metabolic Atlas: A fluorescent protein‐based subcellular localization resource for sorghum enzymes

The Plant Journal, Volume 128, Issue 3, November 2026.
SUMMARY Plant metabolism drives traits essential for productivity and resilience, yet understanding metabolic networks requires subcellular, cellular, and tissue‐level spatial context that remains limited, particularly in crop species. Experimentally derived subcellular localization data for enzymes are sparse, constraining analyses of metabolic ...
Purva Karia, William P. Dwyer, Ava Kloss‐Schmidt, Charles Hawkins, Bo Xue, Daniel Ginzburg, Maxine L. Gutierrez, Ritesh Mewalal, Ian Blaby, David W. Ehrhardt, Seung Y. Rhee   +10 more
wiley   +1 more source