Results 191 to 200 of about 3,647,798 (263)

A Portal‐Preorganized Cucurbit[7]uril‐Ruthenium Conjugate Enables Motif‐Selective Protein Sensing

Angewandte Chemie International Edition, Volume 65, Issue 44, 26 October 2026.
Reprogramming cucurbit[7]uril (CB7) recognition through portal engineering transforms an optically silent host into a motif‐selective photoluminescent receptor. The portal‐preorganized CB7‐Rubpy conjugate directly reports changes in aromatic motif accessibility, enabling optical sensing of protein misfolding and refolding.
Patrick Gruhs, Albert Kraft, Vahideh Mahram, Marco Neumaier, Papri Chakraborty, Emily Janz, Maria Vittoria Balli, Pierre Picchetti, Luca Prodi, Manfred Kappes, Frank Biedermann   +10 more
wiley   +1 more source

Metal-Responsive Up-Regulation of Bifunctional Disulfides for Suppressing Protein Misfolding and Promoting Oxidative Folding. [PDF]

Angew Chem Int Ed Engl
Mori K, Kuramochi T, Matsusaki M, Hashiguchi Y, Okumura M, Saio T, Furukawa Y, Arai K, Muraoka T.   +8 more
europepmc   +1 more source

From Protein Misfolding to Extracellular Matrix Disorganisation: Understanding Disease Pathology in Rare Skeletal Dysplasias. [PDF]

Int J Mol Sci
Dennis EP, Briggs MD.
europepmc   +1 more source

Skin biopsy: an emerging tool for the diagnosis of protein misfolding diseases of the central nervous system. [PDF]

Mol Neurodegener
Zhu W, Sun HL, Wang YJ, Lei X, Bu XL.
europepmc   +1 more source

New Role of Protein Misfolding Corrector in the ER Stress-Inflammation Axis: Possible Therapeutic Indication in Neuronal and Epithelial Tumor Cells. [PDF]

Int J Mol Sci
Pecoraro M, Serra A, Lamberti MJ, Pascale M, Franceschelli S.   +4 more
europepmc   +1 more source

Protein Misfolding and Aggregation as a Mechanistic Link Between Chronic Pain and Neurodegenerative Diseases. [PDF]

Curr Issues Mol Biol
Brezic N, Gligorevic S, Sic A, Knezevic NN.   +3 more
europepmc   +1 more source

Optimization of a High-Throughput Screen for Monitoring Disease-Associated Protein Misfolding and Aggregation in Bacteria. [PDF]

ACS Synth Biol
Delivoria DC, Konia E, Matis I, Skretas G.   +3 more
europepmc   +1 more source

Non-native entanglement protein misfolding observed in all-atom simulations and supported by experimental structural ensembles. [PDF]

Sci Adv
Vu QV, Sitarik I, Jiang Y, Xia Y, Sharma P, Yadav D, Song H, Li MS, Fried SD, O'Brien EP.   +9 more
europepmc   +1 more source

Protein misfolding involving entanglements providesa structural explanation for the origin of stretched-exponential refolding kinetics. [PDF]

Sci Adv
Jiang Y, Xia Y, Sitarik I, Sharma P, Song H, Fried SD, O'Brien EP.   +6 more
europepmc   +1 more source