Results 211 to 220 of about 3,647,798 (263)

Protein Misfolding in Pregnancy: Current Insights, Potential Mechanisms, and Implications for the Pathogenesis of Preeclampsia. [PDF]

Molecules
Medegan Fagla B, Buhimschi IA.
europepmc   +1 more source

A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions. [PDF]

Nat Commun
Eraña H, Sampedro-Torres-Quevedo C, Charco JM, Díaz-Domínguez CM, Peccati F, San-Juan-Ansoleaga M, Vidal E, Gonçalves-Anjo N, Pérez-Castro MA, González-Miranda E, Piñeiro P, Fernández-Veiga L, Galarza-Ahumada J, Fernández-Muñoz E, Perez de Nanclares G, Telling G, Geijo M, Jiménez-Osés G, Castilla J.   +18 more
europepmc   +1 more source

A Perspective on Interdicting in Protein Misfolding for Therapeutic Drug Design: Modulating the Formation of Nonlocal Contacts in α-Synuclein as a Strategy against Parkinson's Disease. [PDF]

J Phys Chem B
Bergasa-Caceres F, Rabitz HA.
europepmc   +1 more source

Sestrin2 drives ER-phagy in response to protein misfolding.

Dev Cell
De Leonibus C, Maddaluno M, Ferriero R, Besio R, Cinque L, Lim PJ, Palma A, De Cegli R, Gagliotta S, Montefusco S, Iavazzo M, Rohrbach M, Giunta C, Polishchuk E, Medina DL, Di Bernardo D, Forlino A, Piccolo P, Settembre C.   +18 more
europepmc   +1 more source

Fitness defects due to cytosolic protein misfolding in S. cerevisiae can be alleviated by decreasing mitochondrial protein import capacity

Zaidi Z, Dash DP, Sharma A, Kundu S, Bhatt S, Rao S, Padia K, Rai M, Chakraborty K.   +8 more
europepmc   +1 more source

Protein Folding and Misfolding on Surfaces [PDF]

International Journal of Molecular Sciences, 2008
Protein folding, misfolding and aggregation, as well as the way misfolded and aggregated proteins affects cell viability are emerging as key themes in molecular and structural biology and in molecular medicine.
Massimo Stefani
exaly   +4 more sources

Cell Death: Protein Misfolding and Neurodegenerative Diseases [PDF]

Apoptosis: an International Journal on Programmed Cell Death, 2009
Several chronic neurodegenerative disorders manifest deposits of misfolded or aggregated proteins. Genetic mutations are the root cause for protein misfolding in rare families, but the majority of patients have sporadic forms possibly related to ...
Stuart A. Lipton, Tomohiro Nakamura
exaly   +2 more sources

Mechanisms of Protein Misfolding: Novel Therapeutic Approaches to Protein-Misfolding Diseases [PDF]

Journal of Molecular Structure, 2016
In protein misfolding, protein molecule acquires wrong tertiary structure, thereby induces protein misfolding diseases. Protein misfolding can occur through various mechanisms. For instance, changes in environmental conditions, oxidative stress, dominant
Ali Saber Abdelhameed, Mohammad Khursheed Siddiqi, Rizwan Hasan Khan   +2 more
exaly   +2 more sources

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Protein Misfolding and Aggregation

Biotechnology Progress, 2008
Interest in the problem of protein misfolding and aggregation has exploded in recent years for two reasons: (1) the sharp rise in the number and volume of therapeutic proteins produced commercially and (2) the recognition of the central role of protein aggregates in degenerative diseases.
Regina M, Murphy, Brent S, Kendrick
openaire   +2 more sources