Results 21 to 30 of about 369,832 (166)

Experimental annotation of post-translational features and translated coding regions in the pathogen Salmonella Typhimurium

BMC Genomics, 2011
Background Complete and accurate genome annotation is crucial for comprehensive and systematic studies of biological systems. However, determining protein-coding genes for most new genomes is almost completely performed by inference using computational ...
Smith Richard D, Venepally Pratap, Monroe Matthew E, Burnet Meagan C, Martin Jessica L, Payne Samuel H, Yoon Hyunjin, Jones Marcus, Porwollik Steffen, Purvine Samuel O, Tolić Nikola, Ansong Charles, Peterson Scott N, Heffron Fred, McClelland Michael, Adkins Joshua N   +15 more
doaj   +1 more source

Characterization of the Proprotein Convertase-Mediated Processing of Peroxidasin and Peroxidasin-like Protein

Antioxidants, 2021
Peroxidasin (PXDN) and peroxidasin-like protein (PXDNL) are members of the peroxidase-cyclooxygenase superfamily. PXDN functions in basement membrane synthesis by forming collagen IV crosslinks, while the function of PXDNL remains practically unknown. In
Hajnal A. Kovács, Enikő Lázár, György Várady, Gábor Sirokmány, Miklós Geiszt   +4 more
doaj   +1 more source

Posttranslational modifications of GLUT4 affect its subcellular localization and translocation [PDF]

, 2013
The facilitative glucose transporter type 4 (GLUT4) is expressed in adipose and muscle and plays a vital role in whole body glucose homeostasis. In the absence of insulin, only ~1% of cellular GLUT4 is present at the plasma membrane, with the vast ...
Bayer, Begum, Birnbaum, Bogan, Bogan, Bogan, Bryant, Cassie Welburn, Chang, Fujita, Garvey, Gill, Giorgino, Govers, Grasbon-Frodl, Gwyn Gould, Haga, Hardy, Herrmann, Hicke, Huang, Ing, James, James, Jessica Sadler, Jeyaraj, Karylowski, Kupriyanova, Lamb, Lau, Lawrence, Lawrence, Leto, Li, Liu, Livingstone, Mahajan, Marsh, Marshall, Marshall, Martin, Matunis, McCormick, Muller, Nia Bryant, Perera, Pessin, Pilch, Piper, Ren, Reusch, Saltiel, Semiz, Shi, Shi, Stöckli, Toh, Urbe, Vannucci, Varki, Watson, Williams, Yang, Yu, Zaarour   +64 more
core   +3 more sources

The 5' → 3' exoribonuclease XRN1/Pacman and its functions in cellular processes and development [PDF]

, 2012
XRN1 is a 5' → 3' processive exoribonuclease that degrades mRNAs after they have been decapped. It is highly conserved in all eukaryotes, including homologs in Drosophila melanogaster (Pacman), Caenorhabditis elegans (XRN1), and Saccharomyces cerevisiae (
Jones, Christopher Iain, Newbury, Sarah Faith, Zabolotskaya, Maria Vasilyevna   +2 more
core   +1 more source

Molecular medicine of microRNAs: structure, function and implications for diabetes [PDF]

, 2008
MicroRNAs (miRNAs) are a family of endogenous small noncoding RNA molecules, of 19–28 nucleotides in length. In humans, up to 3% of all genes are estimated to encode these evolutionarily conserved sequences.
Duncan, Erica Hennessy, Lorraine O'Driscoll, Offield, Schleicher, Zhou   +5 more
core   +1 more source

Dissecting ribosomal particles throughout the kingdoms of life using advanced hybrid mass spectrometry methods

Nature Communications, 2018
The authors demonstrate a 3-tier mass spectrometry approach, including bottom-up and top-down proteomics, as well as native mass spectrometry to provide a detailed description of proteoforms, protein processing and post-translational modifications ...
Michiel van de Waterbeemd, Sem Tamara, Kyle L. Fort, Eugen Damoc, Vojtech Franc, Philipp Bieri, Martin Itten, Alexander Makarov, Nenad Ban, Albert J. R. Heck   +9 more
doaj   +1 more source

Biogenesis of Glyoxysomes [PDF]

, 1980
Biosynthesis of isocitrate lyase, a tetrameric enzyme of the glyoxysomal matrix, was studied in Neurospora crassa, in which the formation of glyoxysomes was induced by a substitution of sucrose medium by acetate medium. * 1.
Neupert, Walter, Zimmermann, Richard
core   +1 more source

Genomic Variability and Post-translational Protein Processing Enhance the Immune Evasion of Mycoplasma hyopneumoniae and Its Interaction With the Porcine Immune System

Frontiers in Immunology, 2020
Mycoplasma hyopneumoniae (M. hyopneumoniae, Mhp) is a geographically widespread and economically devastating pathogen that colonizes ciliated epithelium; the infection of Mhp can damnify the mucociliary functions as well as leading to Mycoplasma ...
Gaojian Li, Enoch Obeng, Jinqi Shu, Jianhong Shu, Jianhong Shu, Jian Chen, Yuehong Wu, Yulong He   +7 more
doaj   +1 more source

Automated assembly of molecular mechanisms at scale from text mining and curated databases

Molecular Systems Biology, 2023
The analysis of omic data depends on machine‐readable information about protein interactions, modifications, and activities as found in protein interaction networks, databases of post‐translational modifications, and curated models of gene and protein ...
John A Bachman, Benjamin M Gyori, Peter K Sorger   +2 more
doaj   +1 more source

An update on transcriptional and post-translational regulation of brain voltage-gated sodium channels [PDF]

, 2015
Voltage-gated sodium channels are essential proteins in brain physiology, as they generate the sodium currents that initiate neuronal action potentials.
Beltran-Alvarez, Pedro, Onwuli, Donatus O.   +1 more
core   +1 more source