Results 21 to 30 of about 215,450 (265)

Acetylome Analysis Identifies SIRT1 Targets in mRNA-Processing and Chromatin-Remodeling in Mouse Liver. [PDF]

PLoS ONE, 2015
Lysine acetylation is a post-translational modification found on numerous proteins, a strategy used in cell signaling to change protein activity in response to internal or external cues.
Sun-Yee Kim, Choon Kiat Sim, Hui Tang, Weiping Han, Kangling Zhang, Feng Xu   +5 more
doaj   +1 more source

Post-translational Processing of the Feline Immunodeficiency Virus Envelope Precursor Protein

Virology, 1993
The synthesis and processing of the envelope glycoprotein precursor of the feline immunodeficiency virus (FIV) isolate FIV-UT113 was investigated in a persistently infected Crandell feline kidney cell line (CRFK) and in an eukaryotic expression system.
Horzinek, M.C., Verschoor, E.J., Hulskotte, E.G., Ederveen, J., Koolen, M.J.M., Rottier, P.J.M.   +5 more
openaire   +3 more sources

Experimental annotation of post-translational features and translated coding regions in the pathogen Salmonella Typhimurium

BMC Genomics, 2011
Background Complete and accurate genome annotation is crucial for comprehensive and systematic studies of biological systems. However, determining protein-coding genes for most new genomes is almost completely performed by inference using computational ...
Smith Richard D, Venepally Pratap, Monroe Matthew E, Burnet Meagan C, Martin Jessica L, Payne Samuel H, Yoon Hyunjin, Jones Marcus, Porwollik Steffen, Purvine Samuel O, Tolić Nikola, Ansong Charles, Peterson Scott N, Heffron Fred, McClelland Michael, Adkins Joshua N   +15 more
doaj   +1 more source

Characterization of the Proprotein Convertase-Mediated Processing of Peroxidasin and Peroxidasin-like Protein

Antioxidants, 2021
Peroxidasin (PXDN) and peroxidasin-like protein (PXDNL) are members of the peroxidase-cyclooxygenase superfamily. PXDN functions in basement membrane synthesis by forming collagen IV crosslinks, while the function of PXDNL remains practically unknown. In
Hajnal A. Kovács, Enikő Lázár, György Várady, Gábor Sirokmány, Miklós Geiszt   +4 more
doaj   +1 more source

Primary structure and post-translational processing of the berne virus peplomer protein

Virology, 1990
The nucleotide sequence of the peplomer (P) protein gene of Berne virus (BEV), the torovirus prototype, was determined. The gene encodes an apoprotein of 1581 amino acids with an Mr of about 178K. The open reading frame was cloned behind the T7 RNA polymerase promoter and its translation product was identified as the BEV P protein precursor by in vivo ...
Snijder, Eric J, Den Boon, Johan A, Spaan, Willy J.M, Weiss, Marianne, Horzinek, Marian C   +4 more
openaire   +2 more sources

Consequences of Disease-causing Mutations on Lubricin Protein Synthesis, Secretion, and Post-translational Processing [PDF]

Journal of Biological Chemistry, 2005
Lubricin, a protein product of the gene PRG4, is a secreted mucin-like proteoglycan that is a major lubricant in articulating joints. Mutations in PRG4 cause the autosomal recessive, human disorder camptodactyly-arthropathy-coxa vara-pericarditis syndrome.
David K, Rhee, Jose, Marcelino, Sulaiman, Al-Mayouf, Deborah K, Schelling, Cynthia F, Bartels, Yajun, Cui, Ronald, Laxer, Raphaela, Goldbach-Mansky, Matthew L, Warman   +8 more
openaire   +2 more sources

Dissecting ribosomal particles throughout the kingdoms of life using advanced hybrid mass spectrometry methods

Nature Communications, 2018
The authors demonstrate a 3-tier mass spectrometry approach, including bottom-up and top-down proteomics, as well as native mass spectrometry to provide a detailed description of proteoforms, protein processing and post-translational modifications ...
Michiel van de Waterbeemd, Sem Tamara, Kyle L. Fort, Eugen Damoc, Vojtech Franc, Philipp Bieri, Martin Itten, Alexander Makarov, Nenad Ban, Albert J. R. Heck   +9 more
doaj   +1 more source

Localization and Post-translational Processing of the Wound-induced Leucine Aminopeptidase Proteins of Tomato [PDF]

Journal of Biological Chemistry, 1996
Leucine aminopeptidase (LAP) is induced by wounding and bacterial pathogen infection in tomato. DNA blot analysis of XbaI-digested lambdalap genomic clones demonstrated that LapA1 and LapA2 cDNAs were encoded by two different LapA genes in the tomato genome. The coding and untranslated regions of LapA1 and LapA2 mRNAs shared more than 93% identity. The
Y Q, Gu, W S, Chao, L L, Walling
openaire   +2 more sources

Genomic Variability and Post-translational Protein Processing Enhance the Immune Evasion of Mycoplasma hyopneumoniae and Its Interaction With the Porcine Immune System

Frontiers in Immunology, 2020
Mycoplasma hyopneumoniae (M. hyopneumoniae, Mhp) is a geographically widespread and economically devastating pathogen that colonizes ciliated epithelium; the infection of Mhp can damnify the mucociliary functions as well as leading to Mycoplasma ...
Gaojian Li, Enoch Obeng, Jinqi Shu, Jianhong Shu, Jianhong Shu, Jian Chen, Yuehong Wu, Yulong He   +7 more
doaj   +1 more source

Automated assembly of molecular mechanisms at scale from text mining and curated databases

Molecular Systems Biology, 2023
The analysis of omic data depends on machine‐readable information about protein interactions, modifications, and activities as found in protein interaction networks, databases of post‐translational modifications, and curated models of gene and protein ...
John A Bachman, Benjamin M Gyori, Peter K Sorger   +2 more
doaj   +1 more source