Localization and Post-translational Processing of the Wound-induced Leucine Aminopeptidase Proteins of Tomato [PDF]
Journal of Biological Chemistry, 1996 Leucine aminopeptidase (LAP) is induced by wounding and bacterial pathogen infection in tomato. DNA blot analysis of XbaI-digested lambdalap genomic clones demonstrated that LapA1 and LapA2 cDNAs were encoded by two different LapA genes in the tomato genome. The coding and untranslated regions of LapA1 and LapA2 mRNAs shared more than 93% identity. The
Yong-Qiang Gu +2 more
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Posttranslational Modifications in Mitochondria: Protein Signaling in the Powerhouse [PDF]
, 2016 There is an intimate interplay between cellular metabolism and the pathophysiology of disease. Mitochondria are essential to maintaining and regulating metabolic function of cells and organs.
Payne, R. Mark, Stram, Amanda R.
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Acetylome Analysis Identifies SIRT1 Targets in mRNA-Processing and Chromatin-Remodeling in Mouse Liver. [PDF]
PLoS ONE, 2015 Lysine acetylation is a post-translational modification found on numerous proteins, a strategy used in cell signaling to change protein activity in response to internal or external cues.
Sun-Yee Kim +5 more
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Post-translational processing of Schizosaccharomyces pombe YPT proteins.
Journal of Biological Chemistry, 1992 ras proteins are post-translationally processed at their carboxyl-terminal CAAX motif by a triplet of modifications: prenylation of C with farnesyl, proteolytic trimming of AAX, and carboxyl-methylation. These modifications co-operate with palmitoylation of nearby sites or a polybasic region to target plasma membrane localization.
John F. Hancock +5 more
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IDENTIFICATION OF THREE NOVEL REGULATORY PATHWAYS INVOLVED IN THE DOWN-REGULATION OF P63 PROTEIN LEVELS [PDF]
, 2010 One way to regulate protein functions is by post-translational modification. Post-translational modifications have an important role in the regulation of biological activity of the protein because they allow both to extend the range of functions of a ...
F. Galli
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Post-translational Processing of the Feline Immunodeficiency Virus Envelope Precursor Protein
Virology, 1993 The synthesis and processing of the envelope glycoprotein precursor of the feline immunodeficiency virus (FIV) isolate FIV-UT113 was investigated in a persistently infected Crandell feline kidney cell line (CRFK) and in an eukaryotic expression system.
Horzinek, M.C. +5 more
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New mechanism for post-translational processing during assembly of a cytoplasmic membrane protein? [PDF]
Journal of Bacteriology, 1981 Insertion of nitrate reductase into the Escherichia coli cytoplasmic membrane was examined by following the fate of pulse-labeled enzyme in both the membrane and cytoplasm during various times after the addition of an unlabeled chase. The polypeptide composition of this labeled enzyme was determined by autoradiography of immunoprecipitated material ...
C H MacGregor, G E McElhaney
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Antioxidants, 2021 Peroxidasin (PXDN) and peroxidasin-like protein (PXDNL) are members of the peroxidase-cyclooxygenase superfamily. PXDN functions in basement membrane synthesis by forming collagen IV crosslinks, while the function of PXDNL remains practically unknown. In
Hajnal A. Kovács +4 more
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Primary structure and post-translational processing of the berne virus peplomer protein
Virology, 1990 The nucleotide sequence of the peplomer (P) protein gene of Berne virus (BEV), the torovirus prototype, was determined. The gene encodes an apoprotein of 1581 amino acids with an Mr of about 178K. The open reading frame was cloned behind the T7 RNA polymerase promoter and its translation product was identified as the BEV P protein precursor by in vivo ...
Johan A. den Boon +4 more
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Obesity Induces Hypothalamic Endoplasmic Reticulum Stress and Impairs Proopiomelanocortin (POMC) Post-translational Processing [PDF]
, 2013 It was shown previously that abnormal prohormone processing or inactive proconverting enzymes that are responsible for this processing cause profound obesity.
Cakir, Isin +6 more
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