Results 291 to 300 of about 750,523 (310)
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Impact of post-translational modifications of proteins on the inflammatory process
Biochemical Society Transactions, 2007PTM (post-translational modification) is the chemical modification of a protein after its translation. The well-studied PTM is phosphorylation, but, recently, PTMs have been re-focused by extensive studies on histone modifications and the discovery of the ubiquitin system.
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Clinica Chimica Acta, 2017
Basic research is showing new mechanisms involved in early immune responses and Neutrophil Extracellular Trap (NET) formation (or NETosis) is of key importance as first line defense against bacteria, virus and protozoa. Enzymatic modification of arginine in citrulline in histones is the prerequisite of NETosis being it necessary for decondensation and ...
Bruschi, Maurizio +9 more
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Basic research is showing new mechanisms involved in early immune responses and Neutrophil Extracellular Trap (NET) formation (or NETosis) is of key importance as first line defense against bacteria, virus and protozoa. Enzymatic modification of arginine in citrulline in histones is the prerequisite of NETosis being it necessary for decondensation and ...
Bruschi, Maurizio +9 more
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Journal of Chromatography A, 1995
It has been demonstrated that good agreement may be observed between computed and experimental isoelectric point (pI) values when proteins of known sequence are focused under denaturing conditions on immobilized pH gradient IPG slabs, at least in the pH range 4-7.5.
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It has been demonstrated that good agreement may be observed between computed and experimental isoelectric point (pI) values when proteins of known sequence are focused under denaturing conditions on immobilized pH gradient IPG slabs, at least in the pH range 4-7.5.
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Post-translational Proteolytic Processing on Intracellular Proteins by Cathepsins and Cystatins
2010Post-translational proteolytic modification by limited proteolysis is not only a biological process that produces biologically active proteins (peptides), but because almost all intracellular biologically active proteins are synthesized as pre-pro forms, ordered limited proteolysis by specific proteases is an essential process.
Masae Takahashi +2 more
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Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1989
Surfactant proteolipid SP-B is a hydrophobic protein of Mr = 8000 identified in organic solvent extracts of pulmonary surfactant. Analysis of the human SP-B RNA predicts that the active surfactant peptide is derived by proteolysis of an Mr = 40,000 precursor.
Virender Kumar Sarin +5 more
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Surfactant proteolipid SP-B is a hydrophobic protein of Mr = 8000 identified in organic solvent extracts of pulmonary surfactant. Analysis of the human SP-B RNA predicts that the active surfactant peptide is derived by proteolysis of an Mr = 40,000 precursor.
Virender Kumar Sarin +5 more
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Protein Transport and Post-translational Processing in Photosystem II Biosynthesis and Homeostasis
2005The biogenesis, repair and homeostasis of Photosystem II (PS II) requires both protein targeting and post-translational modification. The various chloroplast targeting pathways for both nuclear-encoded and chloroplast-encoded proteins are described, with emphasis on the subunits of PS II.
Steven M. Theg, Lan-Xin Shi
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Post-translational processing in the synthesis of egg-specific protein in the silkworm, Bombyx mori
Insect Biochemistry, 1989Abstract The post-translational processing of egg-specific protein (ESP) in developing ovarian follicles of the silkworm, Bombyx mori was analyzed using in vivo and in vitro labeling systems with some radioactive precursors. The labeling with[ 35 S]methionine revealed that ESP is first synthesized as 69 kDa peptide (69K-ESP) which is then ...
Yukihiro Sato, Okitsugu Yamashita
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PROTEOMICS, 2003
AbstractPost‐translational modification of the antiphagocytic M1 protein of Streptococcus pyogenes can influence its binding properties for human immunoglobulin G subclasses and its invasive potential. Current methods of monitoring this modification event involve N‐terminal sequencing and are cumbersome, slow and not amenable to routine analysis.
Terence G Romer, Michael D. P. Boyle
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AbstractPost‐translational modification of the antiphagocytic M1 protein of Streptococcus pyogenes can influence its binding properties for human immunoglobulin G subclasses and its invasive potential. Current methods of monitoring this modification event involve N‐terminal sequencing and are cumbersome, slow and not amenable to routine analysis.
Terence G Romer, Michael D. P. Boyle
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Journal of Theoretical Biology, 1984
A mathematical model is presented that describes first order degradation and post-translational processing of proteins in non-growing and exponentially growing cells. The model applies to proteins that are substrates or products of processing. General equations are presented that can be applied to many different experimental protocols.
Raymond D. Mosteller, Bruce E. Goldstein
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A mathematical model is presented that describes first order degradation and post-translational processing of proteins in non-growing and exponentially growing cells. The model applies to proteins that are substrates or products of processing. General equations are presented that can be applied to many different experimental protocols.
Raymond D. Mosteller, Bruce E. Goldstein
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Archives of Biochemistry and Biophysics, 1993
The two early endosome-associated rab GTP-binding proteins, rab4 and rab5, are suggested to regulate endocytosis. In this report, we examined post-translational processing and membrane association of the two rab proteins. Human rab4 and rab5 were expressed in chicken embryo fibroblasts using a Sindbis virus expression vector.
P.D. Stahl, Guangpu Li
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The two early endosome-associated rab GTP-binding proteins, rab4 and rab5, are suggested to regulate endocytosis. In this report, we examined post-translational processing and membrane association of the two rab proteins. Human rab4 and rab5 were expressed in chicken embryo fibroblasts using a Sindbis virus expression vector.
P.D. Stahl, Guangpu Li
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