Results 101 to 110 of about 2,162,392 (300)

Feeding sainfoin to goats – influence on milk and cheese quality and yield [PDF]

open access: yes, 2012
Although the administration of sainfoin is associated with anthelmintic effects, information on the consequences of feeding this legume on product quality is scarce. In the present study we looked at milk quality and yield of goats fed either sainfoin or
Heckendorn, Felix   +4 more
core  

YoeB toxin is activated during thermal stress. [PDF]

open access: yes, 2015
Type II toxin-antitoxin (TA) modules are thought to mediate stress-responses by temporarily suppressing protein synthesis while cells redirect transcription to adapt to environmental change.
Garza-Sánchez, Fernando   +2 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Protein Homeostasis Database: protein quality control in E.coli

open access: yesBioinformatics, 2019
Abstract Motivation In vivo protein folding is governed by molecular chaperones, that escort proteins from their translational birth to their proteolytic degradation. In E.coli the main classes of chaperones that interact with the nascent chain are trigger factor, DnaK/J and GroEL/ES and several ...
Ramakrishnan, Reshmi   +5 more
openaire   +2 more sources

Introduction to Translation. [PDF]

open access: yes, 2013
We introduce here the inaugural issue of the new scientific journal Translation. The overarching aim of this endeavor is to establish a new forum for a broad spectrum of research in the area of protein synthesis in living systems ranging from structural ...
Hershey, John WB   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Domestic feed sources to farmed Arctic Charr (Salvelinus alpinus) [PDF]

open access: yes, 2010
This study presents an overview of recapturing nutrients from Baltic Sea thru mussel farming and producing mussel meal, detoxification of polluted fish into purified high quality fish meal and oil and introducing microorganisms as waste consumers as well
Muminovic, Muhamed
core   +1 more source

The Interplay among PINK1/PARKIN/Dj-1 Network during Mitochondrial Quality Control in Cancer Biology: Protein Interaction Analysis [PDF]

open access: yes, 2018
PARKIN (E3 ubiquitin ligase PARK2), PINK1 (PTEN induced kinase 1) and DJ-1 (PARK7) are proteins involved in autosomal recessive parkinsonism, and carcinogenic processes.
Lucas, Millikin, Narendra, Santel, Zhang
core   +2 more sources

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